DOI QR코드

DOI QR Code

영상유도하 조직검사의 해석과 판정

Interpretation of Image-Guided Biopsy Results and Assessment

  • 하수민 (서울대학교 의과대학 서울대학교병원 영상의학과) ;
  • 장정민 (서울대학교 의과대학 서울대학교병원 영상의학과)
  • Su Min Ha (Department of Radiology, Seoul National University Hospital, Seoul National College of Medicine) ;
  • Jung Min Chang (Department of Radiology, Seoul National University Hospital, Seoul National College of Medicine)
  • 투고 : 2022.12.04
  • 심사 : 2023.03.10
  • 발행 : 2023.03.01

초록

영상 유도하 유방 조직검사의 성공 여부는 조직검사를 시행하는 당시의 정확한 판단에 근거한 조직검사 유도방식, 기구 선택, 적절한 술기에 의하여 상당 부분 결정되지만, 불충분한 또는 부정확한 검체 채취에 의한 위음성 또는 조직학적 저평가의 한계가 있을 수 있다. 이러한 이유로 영상-병리 합당성 판정을 포함한 조직검사 이후의 적절한 처치와 대응이 매우 중요하다. 조직검사 시 정확한 검체 획득이 이루어지지 않아 암 병변임에도 불구하고, 비특이적인 양성 병변의 병리 결과가 나오는 경우, 영상과 병리 간의 결과 일치 및 불일치 여부를 확인함으로써, 암을 놓치는 일을 막을 수 있다. 이 종설의 목적은 영상 유도하 유방 조직검사 후 결과의 정확한 해석을 위하여 구체적으로 고려할 사항들을 알아보고, 어떻게 적절한 평가를 할 수 있는지 알아보고자 한다.

The success of image-guided breast biopsy depends on the biopsy method, needle selection, and appropriate technique based on the accurate judgment by the radiologist at biopsy. However, insufficient or inappropriate sampling of specimens may result in false-negative results or pathologic underestimation. Therefore, image-pathology concordance assessments after biopsy are essential for appropriate patient management. Particularly, the assessment of image-pathology concordance can avoid false-negative reports of breast cancer as a benign pathology. Therefore, this study aimed to discuss factors that impact the accurate interpretation of image-guided breast biopsy along with the appropriate assessments.

키워드

참고문헌

  1. Vandromme MJ, Umphrey H, Krontiras H. Image-guided methods for biopsy of suspicious breast lesions. J Surg Oncol 2011;103:299-305
  2. Bassett LW, Mahoney MC, Apple SK. Interventional breast imaging: current procedures and assessing for concordance with pathology. Radiol Clin North Am 2007;45:881-894, vii
  3. Youk JH, Kim EK, Kim MJ, Lee JY, Oh KK. Missed breast cancers at US-guided core needle biopsy: how to reduce them. Radiographics 2007;27:79-94
  4. Zhang C, Lewis DR, Nasute P, Hayes M, Warren LJ, Gordon PB. The negative predictive value of ultrasound-guided 14-gauge core needle biopsy of breast masses: a validation study of 339 cases. Cancer Imaging 2012;12:488-496
  5. Uematsu T. How to choose needles and probes for ultrasonographically guided percutaneous breast biopsy: a systematic approach. Breast Cancer 2012;19:238-241
  6. Huang ML, Hess K, Candelaria RP, Eghtedari M, Adrada BE, Sneige N, et al. Comparison of the accuracy of US-guided biopsy of breast masses performed with 14-gauge, 16-gauge and 18-gauge automated cutting needle biopsy devices, and review of the literature. Eur Radiol 2017;27:2928-2933
  7. Mahoney MC, Newell MS. Breast intervention: how I do it. Radiology 2013;268:12-24
  8. Schueller G, Jaromi S, Ponhold L, Fuchsjaeger M, Memarsadeghi M, Rudas M, et al. US-guided 14-gauge core-needle breast biopsy: results of a validation study in 1352 cases. Radiology 2008;248:406-413
  9. Fishman JE, Milikowski C, Ramsinghani R, Velasquez MV, Aviram G. US-guided core-needle biopsy of the breast: how many specimens are necessary? Radiology 2003;226:779-782
  10. Comstock CE. US-guided interventional procedures. In Feig SA, ed. 2005 syllabus: categorical course in diagnostic radiology-breast imaging. Oak Brook, IL: Radiological Society of North America 2005:155-168
  11. Liberman L. Percutaneous image-guided core breast biopsy. Radiol Clin North Am 2002;40:483-500, vi
  12. Liberman L, Drotman M, Morris EA, LaTrenta LR, Abramson AF, Zakowski MF, et al. Imaging-histologic discordance at percutaneous breast biopsy. Cancer 2000;89:2538-2546
  13. Parikh J, Tickman R. Image-guided tissue sampling: where radiology meets pathology. Breast J 2005;11:403-409
  14. Yoo JL, Woo OH, Kim YK, Cho KR, Yong HS, Seo BK, et al. Can MR Imaging contribute in characterizing well-circumscribed breast carcinomas? Radiographics 2010;30:1689-1702
  15. Song SE, Cho N, Chu A, Shin SU, Yi A, Lee SH, et al. Undiagnosed breast cancer: features at supplemental screening US. Radiology 2015;277:372-380
  16. March DE, Raslavicus A, Coughlin BF, Klein SV, Makari-Judson G. Use of breast core biopsy in the United States: results of a national survey. AJR Am J Roentgenol 1997;169:697-701
  17. Shin S, Schneider HB, Cole FJ Jr, Laronga C. Follow-up recommendations for benign breast biopsies. Breast J 2006;12:413-417
  18. Lee CH, Philpotts LE, Horvath LJ, Tocino I. Follow-up of breast lesions diagnosed as benign with stereotactic core-needle biopsy: frequency of mammographic change and false-negative rate. Radiology 1999;212:189-194
  19. Mateo AM, Frankel AM. Is 6-month radiologic imaging necessary after benign breast biopsy? Review of literature and multicenter experience. Am Surg 2015;81:1224-1227
  20. Monticciolo DL, Hajdik RL, Hicks MG, Winford JK, Larkin WR, Vasek JV Jr, et al. Six-month short-interval imaging follow-up for benign concordant core needle biopsy of the breast: outcomes in 1444 cases with long-term follow-up. AJR Am J Roentgenol 2016;207:912-917
  21. Salkowski LR, Fowler AM, Burnside ES, Sisney GA. Utility of 6-month follow-up imaging after a concordant benign breast biopsy result. Radiology 2011;258:380-387
  22. Moon HJ, Jung I, Youk JH, Kim MJ, Kim EK. Short-term follow-up in 6 months is unnecessary for asymptomatic breast lesions with benign concordant results obtained at ultrasonography-guided 14-gauge core needle biopsy. Am J Surg 2016;211:152-158
  23. Adams MC, Falcon S, Mooney BP, Laronga C, Chau A, Drukteinis JS. Short-term imaging follow-up of patients with concordant benign breast core needle biopsies: is it really worth it? Diagn Interv Radiol 2014;20:464-469
  24. Manjoros DT, Collett AE, Alberty-Oller JJ, Frazier TG, Barrio AV. The value of 6-month interval imaging after benign radiologic-pathologic concordant minimally invasive breast biopsy. Ann Surg Oncol 2013;20:3163-3168
  25. Jackman RJ, Marzoni FA Jr, Rosenberg J. False-negative diagnoses at stereotactic vacuum-assisted needle breast biopsy: long-term follow-up of 1,280 lesions and review of the literature. AJR Am J Roentgenol 2009;192:341-351
  26. Shaylor SD, Heller SL, Melsaether AN, Gupta D, Gupta A, Babb J, et al. Short interval follow-up after a benign concordant MR-guided vacuum assisted breast biopsy--is it worthwhile? Eur Radiol 2014;24:1176-1185
  27. Mihalik JE, Krupka L, Davenport R, Tucker L, Toevs C, Smith RS. The rate of imaging-histologic discordance of benign breast disease: a multidisciplinary approach to the management of discordance at a large university-based hospital. Am J Surg 2010;199:319-323; discussion 323
  28. Kim MJ, Kim EK, Lee JY, Youk JH, Park BW, Kim SI, et al. Breast lesions with imaging-histologic discordance during US-guided 14G automated core biopsy: can the directional vacuum-assisted removal replace the surgical excision? Initial findings. Eur Radiol 2007;17:2376-2383
  29. Cho SH, Park SH. Mimickers of breast malignancy on breast sonography. J Ultrasound Med 2013;32:2029-2036
  30. Youk JH, Kim EK, Kim MJ, Kwak JY, Son EJ. Analysis of false-negative results after US-guided 14-gauge core needle breast biopsy. Eur Radiol 2010;20:782-789
  31. Son EJ, Kim EK, Youk JH, Kim MJ, Kwak JY, Choi SH. Imaging-histologic discordance after sonographically guided percutaneous breast biopsy: a prospective observational study. Ultrasound Med Biol 2011;37:1771-1778
  32. Soyder A, Ta,skin F, Ozbas S. Imaging-histological discordance after sonographically guided percutaneous breast core biopsy. Breast Care (Basel) 2015;10:33-37
  33. Yan P, DeMello L, Baird GL, Lourenco AP. Malignancy upgrade rates of radial sclerosing lesions at breast cancer screening. Radiol Imaging Cancer 2021;3:e210036
  34. Hennessy G, Boland MR, Bambrick M, Crone L, Lloyd A, Abdelwahab S, et al. Value of long-term follow-up in surgically excised lesions of uncertain malignant potential in the breast-Is 5 years necessary? Clin Breast Cancer 2022;22:699-704
  35. Patel M, Aripoli A, Chollet-Hinton L, Larson KE, Balanoff CR, Kilgore LJ, et al. Rethinking routine surgical excision for all radial sclerosing lesions of the breast. J Surg Res 2022;279:611-618
  36. Middleton LP, Sneige N, Coyne R, Shen Y, Dong W, Dempsey P, et al. Most lobular carcinoma in situ and atypical lobular hyperplasia diagnosed on core needle biopsy can be managed clinically with radiologic follow-up in a multidisciplinary setting. Cancer Med 2014;3:492-499
  37. Ho CP, Gillis JE, Atkins KA, Harvey JA, Nicholson BT. Interactive case review of radiologic and pathologic findings from breast biopsy: are they concordant? How do I manage the results? Radiographics 2013;33:E149-E152
  38. Bick U, Trimboli RM, Athanasiou A, Balleyguier C, Baltzer PAT, Bernathova M, et al. Image-guided breast biopsy and localisation: recommendations for information to women and referring physicians by the European Society of Breast Imaging. Insights Imaging 2020;11:12