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A Study on the Relationship between Changes in Cerebral Blood Flow and Depression Index after Smoking

  • Gil-Hyun Lee (Department of Clinical Laboratory Science, Wonkwang Health Science University) ;
  • Kyung-Yae Hyun (Department of Clinical Laboratory Science, Dong-Eui University)
  • Received : 2023.02.27
  • Accepted : 2023.03.28
  • Published : 2023.03.31

Abstract

Smoking is one of the three major risk factors for vascular disease along with hypertension and hyperlipidemia. It is true that smoking has a negative effect on the circulatory system, and the frequency of coronary artery disease and peripheral vascular disease is significantly increased in smokers. Many epidemiological studies report that smokers have an approximately two-fold increased risk of coronary artery disease compared to non-smokers. This study was designed to investigate the relationship between cerebral blood flow change and depression index after acute smoking. Cerebral blood flow tests were performed before and after smoking in 8 subjects. Changes in blood flow after smoking were correlated with the depression score and negatively correlated with the depression score. In particular, there was a strong correlation with changes in blood flow in anterior cerebral artery. It is well known that changes in blood flow after smoking have a negative effect. In addition, considering the study that smoking aggravates the symptoms of depression, it was found that smoking and depression are factors that negatively affect each other.

Keywords

Acknowledgement

This project was supported by the National Research Foundation of Korea (2022R1F1A1066041).

References

  1. Ali MF. Transcranial doppler ultrasonography (uses, limitations, and potentials): A review article. Egyptian Journal of Neurosurgery. 2021. 36: 1-9. https://doi.org/10.1186/s41984-020-00096-5
  2. Barutcu I, Esen AM, Degirmenci B, Acar M, Kaya D, Turkmen M, Melek M, Onrat E, Esen OB, Kirma CJ. Acute cigarette smoking-induced hemodynamic alterations in the common carotid artery a transcranial doppler study. Circulation Journal. 2004. 68: 1127-1131. https://doi.org/10.1253/circj.68.1127
  3. Boyajian RA, Otis SM. Acute effects of smoking on human cerebral blood flow: A transcranial doppler ultrasonography study. Journal of Neuroimaging. 2000. 10: 204-208. https://doi.org/10.1111/jon2000104204
  4. Cho DK, Kwon SU, Kim SW, Park JI, Lim SH, Lim SJ, Choi YJ, Sung J, Lee SH, Hong KP. Risk factors and predictors for the progression of carotid atherosclerotic stenosis in Korean adults. Korean Circulation Journal. 2005. 35: 834-840. https://doi.org/10.4070/kcj.2005.35.11.834
  5. Cosgrove KP, Esterlis I, Sandiego C, Petrulli R, Morris ED. Imaging tobacco smoking with pet and spect. The Neuropharmacology of Nicotine Dependence. 2015. 1-17.
  6. Giesecke T, Gracely RH, Williams DA, Geisser ME, Petzke FW, Clauw DJ. The relationship between depression, clinical pain, and experimental pain in a chronic pain cohort. Arthritis & Rheumatism. 2005. 52: 1577-1584. https://doi.org/10.1002/art.21008
  7. Hahn HJ. A standardization study of beck depression inventory in Korea. J Korean Neuropsychiatr Asso. 1982. 25: 487-502.
  8. Hawkins BT, Brown RC, Davis TP. Smoking and ischemic stroke: A role for nicotine? Trends in Pharmacological Sciences. 2002. 23: 78-82. https://doi.org/10.1016/S0165-6147(02)01893-X
  9. Hedlund JL, Vieweg BJ. The hamilton rating scale for depression: A comprehensive review. Journal of Operational Psychiatry. 1979. 10: 149-165.
  10. Helmersson J, Larsson A, Vessby B, Basu SJA. Active smoking and a history of smoking are associated with enhanced prostaglandin f2α, interleukin-6 and f2-isoprostane formation in elderly men. Atherosclerosis. 2005. 181: 201-207. https://doi.org/10.1016/j.atherosclerosis.2004.11.026
  11. Jackson-Koku GJ. Beck depression inventory. Occupational Medicine. 2016. 66: 174-175. https://doi.org/10.1093/occmed/kqv087
  12. Jeon HJ. Depression and suicide. Journal of the Korean Medical Association. 2011. 54: 370-375. https://doi.org/10.5124/jkma.2011.54.4.370
  13. Lesser IM, Mena I, Boone KB, Miller BL, Mehringer CM, Wohl M. Reduction of cerebral blood flow in older depressed patients. Archives of General Psychiatry. 1994. 51: 677-686. https://doi.org/10.1001/archpsyc.1994.03950090009002
  14. Neu P, Schlattmann P, Schilling A, Hartmann A. Cerebrovascular reactivity in major depression: A pilot study. Psychosomatic Medicine. 2004. 66: 6-8. https://doi.org/10.1097/01.PSY.0000107880.03026.54
  15. Oksala NK, Heikkinen M, Mikkelsson J, Pohjasvaara T, Kaste M, Erkinjuntti T, Karhunen PJ. Smoking and the platelet fibrinogen receptor glycoprotein iib/iiia pla1/a2 polymorphism interact in the risk of lacunar stroke and midterm survival. Stroke. 2007. 38: 50-55. https://doi.org/10.1161/01.STR.0000251719.59141.36
  16. Pan B, Jin X, Jun L, Qiu S, Zheng Q, Pan M. The relationship between smoking and stroke: A meta-analysis. Medicine. 2019.98.
  17. Paperwalla KN, Levin TT, Weiner J, Saravay S. Smoking and depression. Medical Clinics. 2004. 88: 1483-1494. https://doi.org/10.1016/j.mcna.2004.06.007
  18. Patton GC, Hibbert M, Rosier MJ, Carlin JB, Caust J, Bowes G. Is smoking associated with depression and anxiety in teenagers? American Journal of Public Health. 1996. 86: 225-230. https://doi.org/10.2105/AJPH.86.2.225
  19. Purkayastha S, Sorond F. Transcranial Doppler ultrasound: technique and application. In Seminars in neurology, Thieme Medical Publishers. American Journal of Public Health. 2012. 32: 411-420. https://doi.org/10.1055/s-0032-1331812
  20. Rogers RL, Meyer JS, Mortel KF, Mahurin RK, Judd B. Decreased cerebral blood flow precedes multi-infarct dementia, but follows senile dementia of alzheimer type. Neurology. 1986. 36: 1-1. https://doi.org/10.1212/WNL.36.1.1
  21. Steger MF, Mann JR, Michels P, Cooper T. Meaning in life, anxiety, depression, and general health among smoking cessation patients. Journal of Psychosomatic Research. 2009. 67: 353-358. https://doi.org/10.1016/j.jpsychores.2009.02.006
  22. Vafaee MS, Gjedde A, Imamirad N, Vang K, Chakravarty MM, Lerch JP, Cumming P. Smoking normalizes cerebral blood flow and oxygen consumption after 12-hour abstention. Journal of Cerebral Blood Flow & Metabolism. 2015. 35: 699-705. https://doi.org/10.1038/jcbfm.2014.246
  23. Xu L, Schooling CM, Chan WM, Lee SY, Leung GM, Lam TS. Smoking and hemorrhagic stroke mortality in a prospective cohort study of older chinese. 2013. 44: 2144-2149.
  24. Yang Y, Grosset DG, Li Q, Lees KR. Identification of echocardiographic "smoke" in a bench model with transcranial doppler ultrasound. Stroke. 2000. 31: 907-914. https://doi.org/10.1161/01.STR.31.4.907
  25. Yang YK, Yao WJ, Yeh TL, Lee IH, Chen PS, Lu RB, Chiu NT, Psychiatry B. Decreased dopamine transporter availability in male smokers-a dual isotope spect study. Progress in NeuroPsychopharmacology and Biological Psychiatry. 2008. 32: 274-279. https://doi.org/10.1016/j.pnpbp.2007.08.018