Korean Journal of Veterinary Research (대한수의학회지)

The Korean Society of Veterinary Science (대한수의학회)
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Hemorrhagic disease caused by bovine viral diarrhea virus-2a in Korean Indigenous Cattle: case reports

  • Hyung-Chul Cho (Department of Animal Science and Biotechnology, College of Ecology and Environmental Science, Kyungpook National University) ;
  • Byoung-Soo Kim (Yeongkwang Veterinary Clinic) ;
  • Dong-Hun Jang (Department of Animal Science and Biotechnology, College of Ecology and Environmental Science, Kyungpook National University) ;
  • Kyung-Hyun Lee (Animal Disease Diagnostic Division, Animal and Plant Quarantine Agency) ;
  • Kyoung-Seong Choi (Department of Animal Science and Biotechnology, College of Ecology and Environmental Science, Kyungpook National University)
  • Received : 2023.01.27
  • Accepted : 2023.03.24
  • Published : 2023.03.31
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Abstract

Two 1-year-old Korean native steers in the same herd presented severe hemorrhagic diarrhea. Case 1 had severe dehydration and died after 3 days, whereas case 2 had anorexia, depression, and severe diarrhea with mucus and blood. Only case 2 was necropsied, and bovine viral diarrhea virus-2a (BVDV2a) was detected in the tissues of its alimentary tract. Gross lesions, including erosion, ulceration, and extensive hemorrhage, were observed in the digestive tract mucosa. Immunohistochemistry revealed marked positive staining for BVDV2a antigen in the large intestine. These findings are indicative of hemorrhagic disease caused by BVDV2a in a native Korean steer.

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Acknowledgement

This research was funded by the Korea Institute of Planning and Evaluation for Technology in Food, Agriculture, and Forestry (IPET) (Grant No. 122017-02-1-HD020).

References

  1. Jokar M, Rahmanian V, Farhoodi M, Abdous A, Shams F, Karami N. Seroprevalence of bovine viral diarrhea virus (BVDV) infection in cattle population in Iran: a systematic review and meta-analysis. Trop Anim Health Prod 2021;53:449.
  2. Ahmed WM, Zaher KS. A field contribution on the relation between reproductive disorders and bovine viral diarrhea virus infection in buffalo-cows. Am Eurasian J Agric Environ Sci 2008;3:736-742.
  3. Houe H. Economic impact of BVDV infection in dairies. Biologicals 2003;31:137-143. https://doi.org/10.1016/S1045-1056(03)00030-7
  4. Pinior B, Firth CL, Richter V, Lebl K, Trauffler M, Dzieciol M, Hutter SE, Burgstaller J, Obritzhauser W, Winter P, Kasbohrer A. A systematic review of financial and economic assessments of bovine viral diarrhea virus (BVDV) prevention and mitigation activities worldwide. Prev Vet Med 2017;137(Pt A):77-92. https://doi.org/10.1016/j.prevetmed.2016.12.014
  5. Yesilbag K, Alpay G, Becher P . Variability and global distribution of subgenotypes of bovine viral diarrhea virus. Viruses 2017;9:128.
  6. Tautz N, Meyers G, Thiel HJ. Pathogenesis of mucosal disease, a deadly disease of cattle caused by a pestivirus. Clin Diagn Virol 1998;10:121-127. https://doi.org/10.1016/S0928-0197(98)00037-3
  7. Donoso A, Inostroza F, Celedon M, Pizarro-Lucero J. Genetic diversity of bovine viral diarrhea virus from cattle in Chile between 2003 and 2007. BMC Vet Res 2018;14:314.
  8. Gomez-Romero N, Basurto-Alcantara FJ, Verdugo-Rodriguez A, Bauermann FV, Ridpath JF. Genetic diversity of bovine viral diarrhea virus in cattle from Mexico. J Vet Diagn Invest 2017;29:362-365. https://doi.org/10.1177/1040638717690187
  9. Seong G, Oem JK, Choi KS. Pathogenetic differences after experimental infection of calves with Korean non-cytopathic BVDV-1 and BVDV-2 isolates. Vet Immunol Immunopathol 2013;156:147-152. https://doi.org/10.1016/j.vetimm.2013.09.010
  10. Bianchi MV, Konradt G, de Souza SO, Bassuino DM, Silveira S, Mosena AC, Canal CW, Pavarini SP, Driemeier D. Natural outbreak of BVDV-1d-induced mucosal disease lacking intestinal lesions. Vet Pathol 2017;54:242-248. https://doi.org/10.1177/0300985816666610
  11. Brodersen BW. Bovine viral diarrhea virus infections: manifestations of infection and recent advances in understanding pathogenesis and control. Vet Pathol 2014;51:453-464. https://doi.org/10.1177/0300985813520250
  12. Cruz RAS, Rodrigues WB, Silveira S, Oliveira VHS, Campos CG, Leite Filho RV, Boabaid FM, Driemeier D, Canal CW, Alfieri AA, Pescador CA, Colodel EM. Mucosal disease-like lesions caused by HoBi-like pestivirus in Brazilian calves in 2010-2011: clinical, pathological, immunohistochemical, and virological characterization. Res Vet Sci 2018;119:116-121. https://doi.org/10.1016/j.rvsc.2018.06.010
  13. Odeon AC, Risatti G, Kaiser GG, Leunda MR, Odriozola E, Campero CM, Donis RO. Bovine viral diarrhea virus genomic associations in mucosal disease, enteritis and generalized dermatitis outbreaks in Argentina. Vet Microbiol 2003;96:133-144. https://doi.org/10.1016/S0378-1135(03)00210-4
  14. Baker JC. The clinical manifestations of bovine viral diarrhea infection. Vet Clin North Am Food Anim Pract 1995;11:425-445. https://doi.org/10.1016/S0749-0720(15)30460-6
  15. Brownlie J. The pathogenesis of bovine virus diarrhoea virus infections. Rev Sci Tech 1990;9:43-59. https://doi.org/10.20506/rst.9.1.491