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Verification of Recycled Plastic Pellets and Mucuna pruriens Extracts Correlation of Antioxidant Efficacy

재활용 플라스틱 펠렛과 벨벳콩(Mucuna pruriens) 추출물의 항산화 효능 상관관계 검증

  • Dong-Geun Han (Department of Cosmeceutical Science, Daegu Hanny University) ;
  • Min-jun Bae (Department of Cosmeceutical Science, Daegu Hanny University) ;
  • GE-GE (Department of Cosmeceutical Science, Daegu Hanny University) ;
  • Hyun-Jeong Kim (R&D Center, HONEST Co., Ltd.) ;
  • Se-Gie Kim (Department of Pharmaceutical Engineering, Daegu Catholic University) ;
  • Bong-Jeon An (Department of Cosmeceutical Science, Daegu Hanny University)
  • 한동근 (대구한의대학교 일반대학원 화장품약리학과) ;
  • 배민준 (대구한의대학교 일반대학원 화장품약리학과) ;
  • 갈격 (대구한의대학교 일반대학원 화장품약리학과) ;
  • 김현정 ((주)허니스트) ;
  • 김세기 (대구가톨릭대학교 제약공학과) ;
  • 안봉전 (대구한의대학교 화장품약리학과)
  • Received : 2022.11.24
  • Accepted : 2023.02.08
  • Published : 2023.03.30

Abstract

In this study, the correlation between recycled plastic pellets and the antioxidant efficacy of the extract of Mucuna pruriens (M. pruriens) was verified. After immersing recycled plastic pellets in M. pruriens extracts, they were stored for 30 days under various temperature conditions, and then analyzed for DPPH radical and ABTS+ radical erasing ability, SOD-like activity, total phenol and flavonoid content. Compared to the existing efficacy, DPPH radical elimination showed less than 30% activity change in ECOTRIA and PCR-PP pellets, and the largest decrease in activity of 46.06% was confirmed in Grico pellets. As a result of measuring ABTS+ radical erasure ability, less than 5% of efficacy change was confirmed in all pellets. As a result of measuring SOD-like activity, all showed a decrease in activity of more than 30%, and as a result of measuring the total phenol and flavonoid content, all pellets showed a tendency to decrease compared to the existing content. Through this results, it was confirmed that the physiological activity of M. pruriens extract decreased and changed by recycled plastic pellets, and based on the results of this study, recycled plastic pellets are believed to affect the existing efficacy and activity stability of M. pruriens extract.

본 연구에서는 재활용 플라스틱 펠렛과 벨벳콩(Mucuna pruriens) 추출물의 항산화 효능 안정도에 대한 상관관계를 검증하였다. 재활용 플라스틱 펠렛을 벨벳콩 추출물에 침지 시킨 다음 다양한 온도 조건에서 30일간 보관한 후 DPPH radical 및 ABTS+ radical 소거능, SOD 유사 활성, 총 페놀 및 플라보노이드 함량 분석을 실시하였다. 기존 효능에 대비하여 DPPH radical 소거능은 ECOTRIA, PCR-PP 펠렛에서 30% 미만의 활성변화를 나타내었으며, Grico 펠렛에서 46.06%의 가장 큰 활성 감소가 확인되었다. ABTS+ radical 소거능 측정결과, 모든 펠렛에서 5% 미만의 효능 변화가 확인되었다. SOD 유사 활성을 측정한 결과, 모두 30% 이상의 활성 감소를 나타내었으며, 총 페놀 및 플라보노이드 함량 측정 결과, 모든 펠렛에서 기존 함량 대비 감소하는 경향을 나타내었다. 이를 통해 재활용 플라스틱 펠렛에 의한 벨벳콩 추출물의 생리활성 감소 및 변화를 확인하였으며, 본 연구 결과를 토대로 재활용 플라스틱 펠렛은 벨벳콩 추출물이 지닌 기존 효능 및 활성의 안정도에 영향을 미치는 것으로 판단된다.

Keywords

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