Journal of the Korean Academy of Child and Adolescent Psychiatry

대한소아청소년정신의학회 (Korean Academy of Child and Adolescent Psychiatry)
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Loss of Acquired Skills: Regression in Young Children With Autism Spectrum Disorders

  • Ye Rim Kim (Department of Psychiatry, Seoul National University College of Medicine) ;
  • Da-Yea Song (Department of Psychiatry, Seoul National University College of Medicine) ;
  • Guiyoung Bong (Department of Psychiatry, Seoul National University Bundang Hospital) ;
  • Jae Hyun Han (Department of Psychiatry, Seoul National University Bundang Hospital) ;
  • Hee Jeong Yoo (Department of Psychiatry, Seoul National University College of Medicine)
  • 투고 : 2022.09.22
  • 심사 : 2022.10.24
  • 발행 : 2023.01.01
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초록

Objectives: Regression, while not a core symptom of autism spectrum disorder (ASD), has been suggested to be a distinct subtype by previous studies. Therefore, this study aimed to explore the prevalence and clinical differences between those with and without regression in children with ASD. Methods: This study includes data from toddlers and young children aged 2-7 years acquired from other projects at Seoul National University Bundang Hospital. The presence and characteristics of regression were explored using question items #11-28 from the Autism Diagnostic Interview-Revised. Chi-square and independent t-tests were used to compare various clinical measurements such as autistic symptoms, adaptative behavior, intelligence, and perinatal factors. Results: Data from 1438 young children (1020 with ASD) were analyzed. The overall prevalence rate of regression, which was mainly related to language-related skills, was 10.2% in the ASD group, with an onset age of 24 months. Regarding clinical characteristics, patients with ASD and regression experienced ASD symptoms, especially restricted and repetitive interests and behaviors, with greater severity than those without regression. Furthermore, there were significant associations between regression and hypertension/placenta previa. Conclusion: In-depth surveillance and proactive interventions targeted at young children with ASD and regression should focus on autistic symptoms and other areas of functioning.

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과제정보

This research was supported by the Bio & Medical Technology Development Program of the National Research Foundation (NRF) funded by the Korean government (MSIT) (No. 2021M3E5D9021878) and by the Institute for Information & Communications Technology Promotion (ITTP) grant funded by the Korean government (MSIT) (No.2019-0-00330, Development of AI Technology for Early Screening of Infant/Child Autism Spectrum Disorders based on Cognition of the Psychological Behavior and Response).

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