Natural Product Sciences

The Korean Society of Pharmacognosy (한국생약학회)
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Total Phenolic Content and Antioxidant Activities of Leaves and Bark Extract of Adenanthera pavonina L.

  • Agustin Yumita (Department of Pharmaceutical Biology, Faculty of Pharmacy and Sciences, Universitas Muhammadiyah) ;
  • Endang Hanani (Department of Pharmaceutical Biology, Faculty of Pharmacy and Sciences, Universitas Muhammadiyah) ;
  • Anis Agustina (Department of Pharmaceutical Biology, Faculty of Pharmacy and Sciences, Universitas Muhammadiyah) ;
  • Feni Damayanti (Department of Pharmaceutical Biology, Faculty of Pharmacy and Sciences, Universitas Muhammadiyah) ;
  • Kadek Niti Priani (Department of Pharmaceutical Biology, Faculty of Pharmacy and Sciences, Universitas Muhammadiyah) ;
  • Sya'idah Nur Fadila (Department of Pharmaceutical Biology, Faculty of Pharmacy and Sciences, Universitas Muhammadiyah)
  • Received : 2022.11.04
  • Accepted : 2023.03.03
  • Published : 2023.03.31
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Abstract

Adenanthera pavonina L. is an important medicinal plant for Indonesian traditional medicine ("Jamu"). The present study is to determine the phenolic content and evaluate the antioxidant activity of ethyl acetate and ethanolic extracts of leaves and bark of A. pavonina. The total phenolic content was determined using the Folin-Ciocalteu reagent methods, and the antioxidant activity was performed by phosphomolybdate assay, through EC50 values. The highest phenolic content (81.379 mg GAE/g) was found in the hydro-ethanolic extract of the leaves and (80.630 mg GAE/g) in the bark. The antioxidant activity of the two samples was 42.270 ㎍/mL (leaves) and 45.261 ㎍/mL (bark). Plants have the potential as drugs with good antioxidant potential and phenolic compound content. Further scientific studies of this plant are supported to evaluate the antioxidant activity using other methods to validate these preliminary experiments properly.

Keywords

Acknowledgement

The author thanks the Scientific Publication Support and Enhancement Unit (UPPI), University of Muhammadiyah Prof. DR. HAMKA who has helped and provided the opportunity to publish this article.

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