Journal of Veterinary Science

The Korean Society of Veterinary Science (대한수의학회)
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Retrospective study of postoperative intraocular pressure and complications in phacoemulsification combined with endoscopic cyclophotocoagulation and phacoemulsification alone in dogs

  • Sol Kim (Department of Veterinary Clinical Sciences, College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University) ;
  • Seonmi Kang (Department of Veterinary Clinical Sciences, College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University) ;
  • Youngseok Jeong (Department of Veterinary Clinical Sciences, College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University) ;
  • Kangmoon Seo (Department of Veterinary Clinical Sciences, College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University)
  • Received : 2022.10.07
  • Accepted : 2023.01.02
  • Published : 2023.01.31
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Abstract

Background: Long-term comparative data of phacoemulsification combined with endoscopic cyclophotocoagulation (phaco-ECP) versus phacoemulsification (phaco) alone in dogs are rare. Objectives: To investigate the effects of ECP on postoperative intraocular pressure (IOP) and complications after phaco in dogs with normal IOP. Methods: Medical records of IOP, conjunctival hyperemia, corneal edema, aqueous flare, posterior synechia, intraocular fibrin, and posterior capsule opacification (PCO) formation in 15 canine eyes that underwent phaco-ECP and 36 eyes that underwent phaco alone were evaluated retrospectively. ECP was applied when either the iridocorneal angle or the ciliary cleft was narrow or closed. Results: The IOP of the phaco-ECP group persisted within the normal range postoperatively. The phaco-ECP group had a shorter period of dorzolamide use than did the phaco group. PCO was formed earlier in the phaco-ECP group than in the phaco group. The phaco-ECP group showed more severe corneal edema than the phaco group at every follow-up visit. Posterior synechia was more severe in the phaco-ECP group than in the phaco group from two weeks until the last follow-up. Conclusions: Although ECP might cause more postoperative complications such as corneal edema and posterior synechia, it could effectively reduce the incidence of IOP increase after phaco in dogs with a high risk of postoperative glaucoma.

Keywords

Acknowledgement

This study was supported by BK21 FOUR Future Veterinary Medicine Leading Education and Research Center and the Research Institute for Veterinary Science (RIVS), College of Veterinary Medicine, Seoul National University, Seoul 08826, Republic of Korea. In addition, this research was supported by Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education (2021R1I1A1A01058695).

References

  1. Michau TM. Surgery of the lens. In: Gelatt KN, editor. Veterinary Ophthalmology. 6th ed. Hoboken: John Wiley & Sons; 2021, 1410-1431.
  2. Moore DL, McLellan GJ, Dubielzig RR. A study of the morphology of canine eyes enucleated or eviscerated due to complications following phacoemulsification. Vet Ophthalmol. 2003;6(3):219-226.  https://doi.org/10.1046/j.1463-5224.2003.00297.x
  3. Shields MB. Intraocular cyclophotocoagulation. Trans Ophthalmol Soc U K. 1986;105(Pt 2):237-241. 
  4. Bras D, Maggio F. Surgical treatment of canine glaucoma: cyclodestructive techniques. Vet Clin North Am Small Anim Pract. 2015;45(6):1283-1305.  https://doi.org/10.1016/j.cvsm.2015.06.007
  5. Lindfield D, Ritchie RW, Griffiths MF. 'Phaco-ECP': combined endoscopic cyclophotocoagulation and cataract surgery to augment medical control of glaucoma. BMJ Open. 2012;2(3):e000578. 
  6. Clement CI, Kampougeris G, Ahmed F, Cordeiro MF, Bloom PA. Combining phacoemulsification with endoscopic cyclophotocoagulation to manage cataract and glaucoma. Clin Exp Ophthalmol. 2013;41(6):546-551.  https://doi.org/10.1111/ceo.12051
  7. Francis BA, Berke SJ, Dustin L, Noecker R. Endoscopic cyclophotocoagulation combined with phacoemulsification versus phacoemulsification alone in medically controlled glaucoma. J Cataract Refract Surg. 2014;40(8):1313-1321.  https://doi.org/10.1016/j.jcrs.2014.06.021
  8. Siegel MJ, Boling WS, Faridi OS, Gupta CK, Kim C, Boling RC, et al. Combined endoscopic cyclophotocoagulation and phacoemulsification versus phacoemulsification alone in the treatment of mild to moderate glaucoma. Clin Exp Ophthalmol. 2015;43(6):531-539.  https://doi.org/10.1111/ceo.12510
  9. Perez Bartolome F, Rodrigues IA, Goyal S, Bloch E, Lim WS, Alaghband P, et al. Phacoemulsification plus endoscopic cyclophotocoagulation versus phacoemulsification alone in primary open-angle glaucoma. Eur J Ophthalmol. 2018;28(2):168-174. https://doi.org/10.5301/ejo.5001034
  10. Ekesten B, Narfstrom K. Correlation of morphologic features of the iridocorneal angle to intraocular pressure in Samoyeds. Am J Vet Res 1991;52(11):1875-1878.  https://doi.org/10.2460/ajvr.1991.52.11.1875
  11. Bedford PG. A practical method of gonioscopy and goniophotography in the dog and cat. J Small Anim Pract. 1973;14(10):601-606.  https://doi.org/10.1111/j.1748-5827.1973.tb06396.x
  12. Yang VY, Miller PE, Keys DA, La Croix NC. Effects of 0.02% netarsudil ophthalmic solution on intraocular pressure of normotensive dogs. Vet Ophthalmol. 2021;24(Suppl 1):87-95.  https://doi.org/10.1111/vop.12736
  13. Tsaousis KT, Panagiotou DZ, Kostopoulou E, Vlatsios V, Stampouli D. Corneal oedema after phacoemulsification in the early postoperative period: a qualitative comparative case-control study between diabetics and non-diabetics. Ann Med Surg (Lond). 2015;5:67-71.  https://doi.org/10.1016/j.amsu.2015.12.047
  14. Kausar A, Farooq S, Akhter W, Akhtar N. Transient corneal edema after phacoemulsification. J Coll Physicians Surg Pak. 2015;25(7):505-509. 
  15. Hogan MJ, Kimura SJ, Thygeson P. Signs and symptoms of uveitis. I. Anterior uveitis. Am J Ophthalmol. 1959;47(5 Pt 2):155-170.  https://doi.org/10.1016/S0002-9394(14)78239-X
  16. Zhao Y, Deng X, Chang P, Hu M, Li Z, Zhang F, et al. Expression profiles of inflammatory cytokines in the aqueous humor of children after congenital cataract extraction. Transl Vis Sci Technol. 2020;9(8):3. 
  17. Lutz EA, Webb TE, Bras ID, Sapienza J, Wilkie D, Gemensky-Metzler A Diode endoscopic cyclophotocoagulation in dogs with primary and secondary glaucoma: 292 cases (2004-2013). Vet Ophthalmol. 2013;16(6):40.
  18. Bras ID, Robbin TE, Wyman M, Rogers AL Diode endoscopic cyclophotocoagulation in canine and feline glaucoma. Vet Ophthalmol. 2005;8(6):449.
  19. Biros DJ, Gelatt KN, Brooks DE, Kubilis PS, Andrew SE, Strubbe DT, et al. Development of glaucoma after cataract surgery in dogs: 220 cases (1987-1998). J Am Vet Med Assoc. 2000;216(11):1780-1786.  https://doi.org/10.2460/javma.2000.216.1780
  20. Rose MD, Mattoon JS, Gemensky-Metzler AJ, Wilkie DA, Rajala-Schultz PJ. Ultrasound biomicroscopy of the iridocorneal angle of the eye before and after phacoemulsification and intraocular lens implantation in dogs. Am J Vet Res. 2008;69(2):279-288.  https://doi.org/10.2460/ajvr.69.2.279
  21. Sigle KJ, Nasisse MP. Long-term complications after phacoemulsification for cataract removal in dogs: 172 cases (1995-2002). J Am Vet Med Assoc. 2006;228(1):74-79.  https://doi.org/10.2460/javma.228.1.74
  22. Klein HE, Krohne SG, Moore GE, Stiles J. Postoperative complications and visual outcomes of phacoemulsification in 103 dogs (179 eyes): 2006-2008. Vet Ophthalmol. 2011;14(2):114-120.  https://doi.org/10.1111/j.1463-5224.2010.00853.x
  23. Hayashi Y, Kato S, Fukushima H, Numaga J, Kaiya T, Tamaki Y, et al. Relationship between anterior capsule contraction and posterior capsule opacification after cataract surgery in patients with diabetes mellitus. J Cataract Refract Surg. 2004;30(7):1517-1520.  https://doi.org/10.1016/j.jcrs.2003.11.045
  24. Beardsley R, Law SK, Caprioli J, Coleman AL, Nouri-Mahdavi K, Hubschman JP, et al. Comparison of outcomes between endoscopic and transcleral cyclophotocoagulation. Vision (Basel). 2017;1(4):24.  https://doi.org/10.3390/vision1040023
  25. Hendrix DVH, Thomasy SM, Gum GG. Physiology of the eye. In: KN Gelatt, editor. Veterinary Ophthalmology. 6th ed. Hoboken: John Wiley & Sons; 2021, 140.
  26. Armstrong RA. Statistical guidelines for the analysis of data obtained from one or both eyes. Ophthalmic Physiol Opt. 2013;33(1):7-14.  https://doi.org/10.1111/opo.12009
  27. Plummer CE, Komaromy AM, Gelatt KN. The canine glaucoma. In: Gelatt KN, Gelatt JP, Plummer CE, editors. Veterinary Ophthalmic Surgery, 2nd ed. St. Louis, Missouri: Elsevier; 2022, 1237.