Journal of Applied Biological Chemistry

  • Volume 66
  • /
  • Pages.227-235
  • /
  • 2023
  • /
  • 1976-0442(pISSN)
  • /
  • 2234-7941(eISSN)
The Korean Society for Applied Biological Chemistry (한국응용생명화학회)
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Characterization of antioxidant and anti-inflammatory activities in the grains of collected Sorghum bicolor varieties

  • Ji Won Seo (Interdisciplinary Program in Smart Science, Kangwon National University) ;
  • Jae Geun Lee (Research Institute of Biotechnology, HwajinBioCosmetic) ;
  • Bimal Kumar Ghimire (Department of Applied Life Science, Konkuk University) ;
  • Myong Jo Kim (Department of Applied Plant Sciences, Division of Bioresource Sciences, Kangwon National University) ;
  • Chang Yeon Yu (Department of Applied Plant Sciences, Division of Bioresource Sciences, Kangwon National University) ;
  • Eun Soo Seong (Department of Applied Plant Sciences, Division of Bioresource Sciences, Kangwon National University)
  • Received : 2023.05.02
  • Accepted : 2023.05.22
  • Published : 2023.12.31
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Abstract

The current study evaluated the presence and concentration of health-promoting phenolic antioxidants in sorghum seed accessions from seven regions in three different countries (Uzbekistan, Myanmar, and the United States). The free radical scavenging activity using the 2,2-diphenyl-1-picrylhydrazyl assay was 13.10±2.37 ㎍/mL in the Uzbekistan sorghum seed extracts, demonstrating the highest antioxidant activity. Additionally, the total phenol content was the highest in the Uzbekistan sorghum seed extracts [157.87±4.04 mg GAE/g (gallic acid equivalents per gram)]. The total flavonoid content was 12.69±0.72 mg QE/g (quercetin equivalents per gram) and represents the highest value in the Myanmar collection. The Uzbekistan collection demonstrated the greatest potential for whitening activity, with the tyrosinase inhibition rate of 79.20±4.15%. The wrinkle improvement function using elastase also showed the highest anti-aging activity of 55.85±4.78% in the same seed extract. The Uzbekistan seed extract had the highest NO production inhibitory activity of 144.35±4.55%. We conclude from these results that the Uzbekistan sorghum seed has excellent antioxidant activity, content of various functional ingredients, and anti-inflammatory activity.

Keywords

Acknowledgement

This study was supported by the Bioherb Research Institute, Kangwon National University, Republic of Korea.

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