한국동물위생학회지 (Korean Journal of Veterinary Service)

  • 제46권4호
  • /
  • Pages.339-348
  • /
  • 2023
  • /
  • 3022-7372(pISSN)
  • /
  • 2287-7630(eISSN)
한국동물위생학회 (The Korean Society of Veterinary Service)
권호 표지
DOI QR코드

DOI QR Code

전북지역 사육 소에서 첫 럼피스킨 발생 보고

The first outbreak of lumpy skin disease in Jeollabuk-do, Korea

  • 추금숙 (전라북도동물위생시험소) ;
  • 정우리 (전라북도동물위생시험소) ;
  • 양승혁 (전라북도동물위생시험소) ;
  • 이명찬 (전라북도동물위생시험소서부지소) ;
  • 손구례 (전라북도동물위생시험소서부지소)
  • Keum Sook Chu (Jeollabuk-do Institute Livestock and Veterinary Research) ;
  • Woo Ri Jung (Jeollabuk-do Institute Livestock and Veterinary Research) ;
  • Seung Hyuk Yang (Jeollabuk-do Institute Livestock and Veterinary Research) ;
  • Myung Chan Lee (Jeollabuk-do Institute Livestock and Veterinary Research) ;
  • Ku Rye Shon (Jeollabuk-do Institute Livestock and Veterinary Research)
  • 투고 : 2023.12.07
  • 심사 : 2023.12.11
  • 발행 : 2023.12.30
PDF 다운로드
⟨ 이전 논문 다음 논문 ⟩

초록

The outbreak of lumpy skin disease (LSD), caused by LSD virus (LSDV), in Jeollabuk-do was first confirmed at a Korean cattle farm in Buan-gun on October 24, 2023. Afterwards, thirteen cases (twelve cases in Gochang-gun and a case in Imsil-gun) were further confirmed, resulting in a total of fourteen cases over 25 days until November 17, 2023. Clinical examination were conducted on infected and co-habitting cattle from the LSD-affected farms with particular focus on the presence of nodules throughout the body such as head, neck, chest, femur, head, and perineum. As a results, abnormal clinical signs were observed in fifteen cows: loss of appetite in six cows, high fever in three cows, eye mucosal nodules in a cow, nasal mucosal nodules in six cows, nodules on perineum in five cows, scrotum nodules in two cows, papillary nodules in a cow, and/or skin nodules in eleven cows. By the PCR methods, the common gene of capripox virus and/or the specific gene of LSDV were detected in 35 of the 69 cows tested this study. In the Farm1, capripox virus-specific gene, LSDV wild strain-specific gene, and LSDV vaccine strain-spcific gene were simultaneously detected in affected cows, indicating the cattle farm was affected by various strain of LSDV. As a result of combining clincal examination and PCR test, it was found that clinically and subclinically infeted cows coexist in the LSDV-infected farms. These finding in this study will be a great help in diagnosis and prevention of the LSD in Korean cattle farms.

키워드

참고문헌

  1. Akther M, Akter SH, Sarker S, Aleri JW, Annandale H, Abraham S, Uddin JM. 2023. Global burden of lumpy skin disease, outbreaks, and future challenges. Viruses 15: 1861. 
  2. Al-Salihi KA. 2014. Lumpy Skin disease: Review of literature. MRVSA 3: 6-23. 
  3. Alkhamis MA, VanderWaal K. 2016. Spatial and temporal epidemiology of lumpy skin disease in the Middle East, 2012-2015. Front Vet Sci 3: 1-12.  https://doi.org/10.3389/fvets.2016.00019
  4. Amenu A, Bkuma F, Abafaji G, Abera D. 2018. Review on epidemiological aspects and economic impact of lumpy skin disease. Dairy and Vet Sci J 7: 555716. 
  5. Arjkumpa O, Suwannaboon M, Boonrod M, Punyawan I, Liangchaisiri S, Laobannue P, Lapchareonwong C, Sansri C, Kuatako N, Panyasomboonying P, Uttarak P, Buamithup N, Sansamur C, Punyapornwithaya V. 2022. The first lumpy skin disease outbreak in Thailand (2021): Epidemiological Features and Spatio-Temporal Analysis. Front Vet Sci 8: 799065. 
  6. Biosecurity New Zealand. 2022. Technical Advice, Risk of lumpy skin disease via import of cattle and buffalo meat and meat products for human and animal consumption. Import Risk Analysis NZ Government.
  7. Chibssa TR, Sombo M, Lichoti JK, Adam TIB, Liu Y, Elraouf YA, et al. 2021. Molecular analysis of East African lumpy skin disease viruses reveals a mixed isolate with features of both vaccine and field isolates. Microorganisms 9:1142. 
  8. Das, M, Chowdhury MSR, Akter S, Mondal A.K, Uddin MJ, Rahman MM, Rahman MM. 2021. An updated review on lumpy skin disease: a perspective of Southeast Asian countries. J Adv Biotechnol Exp Ther 4: 322-333.  https://doi.org/10.5455/jabet.2021.d133
  9. Haegeman A, Leeuw ID, Mostin L, Campe WV, Aerts L, Venter E, Tuppurainen E, Saegerman, C, Clercq KD. 2021. Comparative evaluation of lumpy skin disease virus-based live attenuated vaccines. Vaccines 9: 473. 
  10. Haegeman A, Leeuw ID, Philips W, Regge ND. 2023. Development and validation of a new DIVA realtime PCR allowing to differentiate wild-type lumpy skin disease virus strains, including the Asian recombinant strains, from Neethling-based vaccine strains. Viruses 15: 870. 
  11. Haegeman A, Zro K, Vandenbussche F, Demeestere L, Van Campe W, Ennaji MM, DeClerq K. 2013. Development and validation of three capripoxvirus realtime PCRs for parallel testing. J Virol Methods 193: 446-451.  https://doi.org/10.1016/j.jviromet.2013.07.010
  12. Hamdi J, Munyanduki H, Tadlaoui KO, Harrak ME, Fihri OF. 2021. Capripoxvirus infections in ruminants: A review. Microorganisms 9: 902. 
  13. Klement E, Broglia A, Antoniou SE, Tsiamadis V, Plevraki E, Petrovic T, Polacek V, Debeljak Z, Miteva A, Alexandrov T, Marojevic D, Pite L, Kondratenko V, Atanasov Z, Gubbins S, Stegeman A, Abrahantes JC. 2020. Neethling vaccine proved highly effective in controlling lumpy skin disease epidemics in the Balkans. Prev Veter Med 181: 104595. 
  14. Kumar N, Tripathi BN. 2022. A serious skin virus epidemic sweeping through the Indian subcontinent is a threat to the livelihood of farmers. Virulence 13: 1943-1944.  https://doi.org/10.1080/21505594.2022.2141971
  15. Li L, Qi C, Li J, Nan W, Wang Y, Chang X, Chi T, Gong M, Ha D, De J, Ma L, Wu X. 2022. Quantitative real-time PCR detection and analysis of a lumpy skin disease outbreak in inner Mongolia autonomous region, China. Front Vet Sci 9: 1-8.  https://doi.org/10.3389/fvets.2022.936581
  16. Moudgil G, Chadha J, Khullar L, Chhibber S, Harjai K. 2023. Lumpy skin disease : A comprehensive review on virus biology, pathogenesis, and sudden global emergence. Preprints 2023020074. 
  17. Pandey N, Hopker A, Prajapati G, Rahangdale N, Gore K, Sargison N. 2022. Observations on presumptive lumpy skin disease in native cattle and Asian water buffaloes around the tiger reserves of the central Indian highlands. N Z Vet J 70: 101-108.  https://doi.org/10.1080/00480169.2021.1984335
  18. Prozesky L, Barnard BJH. 1982. A Study of the pathology of lumpy skin-disease in cattle. Onderstepoort J Vet Res 49: 167-175. 
  19. Roche X, Rozstalnyy A, TagoPacheco D, Pittiglio C, Kamata A, Beltran Alcrudo D, Bisht K, Karki S, Kayamori J, Larfaoui F, Raizman E, VonDobschuetz S, Dhingra MS, Sumption K. 2020. Introduction and spread of lumpy skin disease in South, East and Southeast Asia: Qualitative risk assessment and management. FAO animal production and health Paper 183. 
  20. Roth JA. 2007. Animal disease information and prevention materials developed by the center for food security and public health. Iowa State Univ Anim Ind Rep 4(1). 
  21. Sprygin A, Pestova Y, Bjadovskaya O, Prutnikov P, Zinyakov N, Kononova S, Ruchnova O, Lozovoy D, Chvala I, Kononov A. 2020. Evidence of recombination of vaccine strains of lumpy skin disease virus with field strains, causing disease. PLoS ONE 15: e0232584. 
  22. Sprygin A, Sainnokhoi T, Gombo-Ochir D, Tserenchimed T, Tsolmon A, Byadovskaya O, Ankhanbaatar U, Mazloum A, Korennoy F, Chvala I. 2022. Genetic characterization and epidemiological analysis of the first lumpy skin disease virus outbreak in Mongolia, 2021. Transbound Emerg Dis 69: 3664-3672.  https://doi.org/10.1111/tbed.14736
  23. Tran HTT, Truong AD, Dang AK, Ly DV, Nguyen CT, Chu NT, Hoang TV, Nguyen HT, Nguyen VT, Dang HV. 2021. Lumpy skin disease outbreaks in Vietnam, 2020. Transbound Emerg Dis 68: 977-980.  https://doi.org/10.1111/tbed.14022
  24. Tulman ER, Afonso CL, Lu Z, Zsak L, Kutish GF, Rock DL. 2001. Genome of lumpy skin disease virus. J Virol 75: 7122-7130.  https://doi.org/10.1128/JVI.75.15.7122-7130.2001
  25. Tuppurainen ESM, Oura CAL. 2012. Review: Lumpy skin disease: An emerging threat to Europe, the Middle East and Asia. Transbound Emerg Dis 59: 40-48.  https://doi.org/10.1111/j.1865-1682.2011.01242.x
  26. WOAH. 2022. Frequently Asked Questions(FAQ) on Lumpy Skin Disease(LSD) https://www.woah.org/app/uploads/2022/06/faq-LSD-faired-v2-4forpublication.pdf