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Pathologic conditions associated with impacted third molars: A retrospective study of panoramic radiographs in a Southern Brazilian population

  • Gabriela Brum Cardoso (Dental Sciences Post-Graduation Program, Federal University of Santa Maria) ;
  • Gleica Dal' Ongaro Savegnago (Dental Sciences Post-Graduation Program, Federal University of Santa Maria) ;
  • Waneza Dias Borges Hirsch (Department of Stomatology, Federal University of Santa Maria) ;
  • Mariana Boessio Vizzotto (Department of Surgery and Orthopedics, Federal University of Rio Grande do Sul) ;
  • Gabriela Salatino Liedke (Department of Stomatology, Federal University of Santa Maria)
  • 투고 : 2023.02.13
  • 심사 : 2023.07.14
  • 발행 : 2023.12.31

초록

Purpose: This study investigated the prevalence of developmental and acquired pathologic conditions associated with impacted third molars (3Ms) in a Southern Brazilian population and evaluated whether demographic and tooth characteristics were correlated with the presence of bone or tooth lesions. Materials and Methods: Panoramic radiographs were assessed for developmental (bone-related) or acquired (tooth-related) pathoses associated with impacted upper or lower 3Ms. Data on tooth positioning, tooth development, and patient demographics were collected. A trained, calibrated postgraduate student evaluated all images. Binary and multivariate logistic regression models were used to assess associations between outcomes and the demographic and radiographic variables. The threshold for statistical significance was set at 5% (P<0.05). Results: The sample comprised panoramic radiographs from 2054 patients, predominantly female (59.2%), with a mean age of 27.2±11.5 years. Overall, 4066 impacted 3Ms were evaluated, revealing 471 (11.6%) developmental and 710 (17.5%) acquired pathoses. Among the developmental pathoses, 460 (95.2%) were indicative of dentigerous cysts. Male sex, lower 3M location, vertical or distoangular positioning, and incomplete root formation were associated with an elevated likelihood of developmental pathology. Lower tooth position, complete root formation, and partial eruption were linked to an increased probability of an acquired pathology in the third or second molar. Conclusion: The prevalence of pathologic conditions associated with impacted 3Ms was low. Male sex, lower 3M placement, horizontal or distoangular positioning, and incomplete root formation were associated with developmental pathoses, while lower tooth position, complete root formation, and partial eruption were related to acquired pathoses.

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참고문헌

  1. Carter K, Worthington S. Predictors of third molar impaction: a systematic review and meta-analysis. J Dent Res 2016; 95: 267-76. https://doi.org/10.1177/0022034515615857
  2. Camargo IB, Melo AR, Fernandes AV, Cunningham LL, Laureano Filho JR, Van Sickels JE. Decision making in third molar surgery: a survey of Brazilian oral and maxillofacial surgeons. Int Dent J 2015; 65: 169-77. https://doi.org/10.1111/idj.12165
  3. Shoshani-Dror D, Shilo D, Ginini JG, Emodi O, Rachmiel A. Controversy regarding the need for prophylactic removal of impacted third molars: an overview. Quintessence Int 2018; 49: 653-62.
  4. Toedtling V, Devlin H, O'Malley L, Tickle M. A systematic review of second molar distal surface caries incidence in the context of third molar absence and emergence. Br Dent J 2020; 228: 261-6. https://doi.org/10.1038/s41415-020-1255-x
  5. Vandeplas C, Vranckx M, Hekner D, Politis C, Jacobs R. Does retaining third molars result in the development of pathology over time? A systematic review. J Oral Maxillofac Surg 2020; 78: 1892-908. https://doi.org/10.1016/j.joms.2020.06.014
  6. Friedman JW. The prophylactic extraction of third molars: a public health hazard. Am J Public Health 2007; 97: 1554-9. https://doi.org/10.2105/AJPH.2006.100271
  7. Zawawi KH, Melis M. The role of mandibular third molars on lower anterior teeth crowding and relapse after orthodontic treatment: a systematic review. ScientificWorldJournal 2014; 2014: 615429.
  8. Duarte-Rodrigues L, Miranda EF, Souza TO, de Paiva HN, Falci SG, Galvao EL. Third molar removal and its impact on quality of life: systematic review and meta-analysis. Qual Life Res 2018; 27: 2477-89. https://doi.org/10.1007/s11136-018-1889-1
  9. Hounsome J, Pilkington G, Mahon J, Boland A, Beale S, Kotas E, et al. Prophylactic removal of impacted mandibular third molars: a systematic review and economic evaluation. Health Technol Assess 2020; 24: 1-116. https://doi.org/10.3310/hta24300
  10. van der Linden W, Cleaton-Jones P, Lownie M. Diseases and lesions associated with third molars. Review of 1001 cases. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1995; 79: 142-5. https://doi.org/10.1016/S1079-2104(05)80270-7
  11. Adeyemo WL. Do pathologies associated with impacted lower third molars justify prophylactic removal? A critical review of the literature. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2006; 102: 448-52. https://doi.org/10.1016/j.tripleo.2005.08.015
  12. Shin SM, Choi EJ, Moon SY. Prevalence of pathologies related to impacted mandibular third molars. Springerplus 2016; 5: 915.
  13. Mello FW, Melo G, Kammer PV, Speight PM, Rivero ER. Prevalence of odontogenic cysts and tumors associated with impacted third molars: a systematic review and meta-analysis. J Craniomaxillofac Surg 2019; 47: 996-1002. https://doi.org/10.1016/j.jcms.2019.03.026
  14. American Association of Oral and Maxillofacial Surgeons. Management of impacted third molar teeth [Internet]. American Association of Oral and Maxillofacial Surgeons: Rosemont; 2016 [ctied 2023 Feb 11]. Available from https://www.aaoms.org/docs/govt_affairs/advocacy_white_papers/management_third_molar_white_paper.pdf.
  15. Sebastiani AM, Todero SR, Gabardo G, da Costa DJ, Rebelatto NL, Scariot R. Intraoperative accidents associated with surgical removal of third molars. Braz J Oral Sci 2014; 13: 276-80. https://doi.org/10.1590/1677-3225v13n4a07
  16. Atieh MA. Diagnostic accuracy of panoramic radiography in determining relationship between inferior alveolar nerve and mandibular third molar. J Oral Maxillofac Surg 2010; 68: 74-82. https://doi.org/10.1016/j.joms.2009.04.074
  17. Matzen LH, Wenzel A. Efficacy of CBCT for assessment of impacted mandibular third molars: a review - based on a hierarchical model of evidence. Dentomaxillofac Radiol 2015; 44: 20140189.
  18. Tantanapornkul W, Mavin D, Prapaiphittayakun J, Phipatboonyarat N, Julphantong W. Accuracy of panoramic radiograph in assessment of the relationship between mandibular canal and impacted third molars. Open Dent J 2016; 10: 322-9. https://doi.org/10.2174/1874210601610010322
  19. Sedentexct Radiation protection: cone beam CT for dental and maxillofacial radiology. Evidence based guidelines 2011 (v2.0) [Internet]. SEDENTEXCT project; 2011 [cited 2023 Feb 10]. Available from: Available from: https://sedentexct.eu/content/guidelines-cbct-dental-and-maxillofacial-radiology.htm. Cone Beam CT for Dental and Maxillofacial Radiology (Evidencebased Guidelines). Radiat Prot Eur Comm 2012; 1-156.
  20. Matzen LH, Berkhout E. Cone beam CT imaging of the mandibular third molar: a position paper prepared by the European Academy of DentoMaxilloFacial Radiology (EADMFR). Dentomaxillofac Radiol 2019; 48: 20190039.
  21. Jaju PP, Jaju SP. Cone-beam computed tomography: time to move from ALARA to ALADA. Imaging Sci Dent 2015; 45: 263-5. https://doi.org/10.5624/isd.2015.45.4.263
  22. Costa MG, Pazzini CA, Pantuzo MC, Jorge ML, Marques LS. Is there justification for prophylactic extraction of third molars? A systematic review. Braz Oral Res 2013; 27: 183-8. https://doi.org/10.1590/S1806-83242013000100024
  23. Patil S, Halgatti V, Khandelwal S, Santosh BS, Maheshwari S. Prevalence of cysts and tumors around the retained and unerupted third molars in the Indian population. J Oral Biol Craniofac Res 2014; 4: 82-7. https://doi.org/10.1016/j.jobcr.2014.07.003
  24. Ryalat S, AlRyalat SA, Kassob Z, Hassona Y, Al-Shayyab MH, Sawair F. Impaction of lower third molars and their association with age: radiological perspectives. BMC Oral Health 2018; 18:58.
  25. Ghaeminia H, Nienhuijs ME, Toedtling V, Perry J, Tummers M, Hoppenreijs TJ, et al. Surgical removal versus retention for the management of asymptomatic disease-free impacted wisdom teeth. Cochrane Database Syst Rev 2020; 5: CD003879.
  26. Vranckx M, Lauwens L, Moreno Rabie C, Politis C, Jacobs R. Radiological risk indicators for persistent postoperative morbidity after third molar removal. Clin Oral Investig 2021; 25: 4471-80. https://doi.org/10.1007/s00784-020-03759-7
  27. Haddad Z, Khorasani M, Bakhshi M, Tofangchiha M, Shalli Z. Radiographic position of impacted mandibular third molars and their association with pathological conditions. Int J Dent 2021; 2021: 8841297.
  28. Pell GJ, Gregory GT. Impacted mandibular third molars: classification and modified technique for removal. Dent Dig 1933; 39: 330-8.
  29. Winter GB. Principles of exodontia as applied to the impacted third molar: a complete treatise on the operative technic with clinical diagnoses and radiographic interpretations. St. Louis: American Medical Book; 1926. pp. 21-58.
  30. Nolla CM. The development of permanent teeth. J Dent Child 1960; 27: 254-66.
  31. Kruger E, Thomson WM, Konthasinghe P. Third molar outcomes from age 18 to 26: findings from a population-based New Zealand longitudinal study. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2001; 92: 150-5. https://doi.org/10.1067/moe.2001.115461
  32. Baykul T, Saglam AA, Aydin U, Basak K. Incidence of cystic changes in radiographically normal impacted lower third molar follicles. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2005; 99: 542-5. https://doi.org/10.1016/j.tripleo.2004.08.010
  33. Haghanifar S, Moudi E, Seyedmajidi M, Mehdizadeh M, Nosrati K, Abbaszadeh N, et al. Can the follicle-crown ratio of the impacted third molars be a reliable indicator of pathologic problem? J Dent(Shiraz) 2014; 15: 187-91.
  34. Chu FC, Li TK, Lui VK, Newsome PR, Chow RL, Cheung LK. Prevalence of impacted teeth and associated pathologies - a radiographic study of the Hong Kong Chinese population. Hong Kong Med J 2003; 9: 158-63.
  35. Al-Khateeb TH, Bataineh AB. Pathology associated with impacted mandibular third molars in a group of Jordanians. J Oral Maxillofac Surg 2006; 64: 1598-602. https://doi.org/10.1016/j.joms.2005.11.102
  36. Claudia A, Barbu HM, Adi L, Gultekin A, Reiser V, Gultekin P, et al. Relationship between third mandibular molar angulation and distal cervical caries in the second molar. J Craniofac Surg 2018; 29: 2267-71. https://doi.org/10.1097/SCS.0000000000004505
  37. Miranda da Rosa F, Oliveira MG, Palmeira da Silva V, Rados PV, Sant'Ana Filho M. Relationship between the positions of impacted third molars and the presence of dentigerous cysts. Gen Dent 2015; 63: 43-6.
  38. Silva K, Alves A, Correa M, Etges A, Vasconcelos AC, Gomes AP, et al. Retrospective analysis of jaw biopsies in young adults. A study of 1599 cases in Southern Brazil. Med Oral Patol Oral Cir Bucal 2017; 22: e702-7. https://doi.org/10.4317/medoral.21918
  39. Marques J, Montserrat-Bosch M, Figueiredo R, Vilchez-Perez MA, Valmaseda-Castellon E, Gay-Escoda C. Impacted lower third molars and distal caries in the mandibular second molar. Is prophylactic removal of lower third molars justified? J Clin Exp Dent 2017; 9: e794-8. https://doi.org/10.4317/jced.53919
  40. Shoaee S, Khazaei P, Mashhadiabbas F, Varshosaz M, Sharifi F, Hessari H. Association between tooth impaction and odontogenic lesions: a matched case-control study. Med J Islam Repub Iran 2018; 32: 57.
  41. Pinkhasov RM, Wong J, Kashanian J, Lee M, Samadi DB, Pinkhasov MM, et al. Are men shortchanged on health? Perspective on health care utilization and health risk behavior in men and women in the United States. Int J Clin Pract 2010; 64: 475-87. https://doi.org/10.1111/j.1742-1241.2009.02290.x
  42. Haidry N, Singh M, Mamatha NS, Shivhare P, Girish HC, Ranganatha N, et al. Histopathological evaluation of dental follicle associated with radiographically normal impacted mandibular third molars. Ann Maxillofac Surg 2018; 8: 259-64. https://doi.org/10.4103/ams.ams_215_18
  43. Fisher EL, Garaas R, Blakey GH, Offenbacher S, Shugars DA, Phillips C, et al. Changes over time in the prevalence of caries experience or periodontal pathology on third molars in young adults. J Oral Maxillofac Surg 2012; 70: 1016-22. https://doi.org/10.1016/j.joms.2011.10.016
  44. Kasper KA, Austin D, Kvanli AH, Rios TR, Senn DR. Reliability of third molar development for age estimation in a Texas hispanic population: a comparison study. J Forensic Sci 2009; 54: 651-7. https://doi.org/10.1111/j.1556-4029.2009.01031.x
  45. Berkvens ME, Fairgrieve SI, Keenan S. A comparison of techniques in age estimation using the third molar. Can Soc Forensic Sci J 2017; 50: 74-83. https://doi.org/10.1080/00085030.2017.1281632
  46. Kambalimath DH, Kambalimath HV, Agrawal SM, Singh M, Jain N, Anurag B, et al. Prevalence and distribution of odontogenic cyst in indian population: a 10 year retrospective study. J Maxillofac Oral Surg 2014; 13: 10-5. https://doi.org/10.1007/s12663-012-0450-y
  47. de Oliveira DM, de Souza Andrade ES, da Silveira MM, Camargo IB. Correlation of the radiographic and morphological features of the dental follicle of third molars with incomplete root formation. Int J Med Sci 2008; 5: 36-40. https://doi.org/10.7150/ijms.5.36
  48. Kotrashetti VS, Kale AD, Bhalaerao SS, Hallikeremath SR. Histopathologic changes in soft tissue associated with radio-graphically normal impacted third molars. Indian J Dent Res 2010; 21: 385-90. https://doi.org/10.4103/0970-9290.70809
  49. Leone SA, Edenfield MJ, Cohen ME. Correlation of acute pericoronitis and the position of the mandibular third molar. Oral Surg Oral Med Oral Pathol 1986; 62: 245-50. https://doi.org/10.1016/0030-4220(86)90001-0