한국환경보건학회지 (Journal of Environmental Health Sciences)

  • 제49권6호
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  • Pages.289-294
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  • 2023
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  • 1738-4087(pISSN)
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  • 2233-8616(eISSN)
한국환경보건학회 (Korean Society of Environmental Health)
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HPLC를 이용한 국내 유통 막걸리 내 인공감미료 함량 조사

Investigation of Artificial Sweeteners in Makgeolli Distributed in South Korea Using HPLC

  • 신혜원 (을지대학교 보건환경안전학과) ;
  • 김민서 (을지대학교 보건환경안전학과) ;
  • 김예지 (을지대학교 보건환경안전학과) ;
  • 박나연 (을지대학교 보건환경안전학과) ;
  • 고영림 (을지대학교 보건환경안전학과)
  • Hyewon Shin (Department of Health, Environment & Safety, Eulji University) ;
  • Minseo Kim (Department of Health, Environment & Safety, Eulji University) ;
  • Yeji Kim (Department of Health, Environment & Safety, Eulji University) ;
  • Nayeon Park (Department of Health, Environment & Safety, Eulji University) ;
  • Younglim Kho (Department of Health, Environment & Safety, Eulji University)
  • 투고 : 2023.11.27
  • 심사 : 2023.12.26
  • 발행 : 2023.12.31
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초록

Background: Artificial sweeteners are chemically synthesized substances used to add sweetness to foods. Representative substances include aspartame and acesulfame-K, which are 200 times sweeter than sugar. Recently, the IARC classified aspartame as class 2B, but Ministry of Food and Drug Safety of South Korea announced that it would maintain the current usage standards. Acesulfame-K, which has the potential to cause cancer, was excluded from the list of possible carcinogens, raising questions about its safety. According to a survey by the Consumers Union of Korea, 85% of makgeolli includes artificial sweeteners, but the content labelling is not indicated. It is necessary to accurately determine the intake of artificial sweeteners through makgeolli. Objectives: This study aims to evaluate the safety of makgeolli consumption by identifying the content of artificial sweeteners (aspartame, acesulfam-K) and preservatives (sorbic acid). Methods: Twenty makgeolli samples were purchased from large supermarkets and convenience stores by referring to the sales ranking of makgeolli products distributed in South Korea and the purchase ranking from online sites. The sample was sonicated to remove alcohol and carbon dioxide. Nine mL of acetonitrile was mixed with 1 mL of the prepared sample, centrifuged, and the supernatant was filtered and analyzed using HPLC. Results: As a result of the analysis, aspartame was detected in 17 products and acesulfame-K was detected in ten. The ADI of aspartame (40 mg/kg·bw/day) is higher than the EDI based on the maximum concentration 126.5 ㎍/mL. The ADI of acesulfame-K (15 mg/kg·bw/day) is higher than the EDI based on the highest concentration of 82.96 ㎍/mL. Although the health risk is low, IARC has raised the possibility of aspartame causing carcinogenesis, so there is a need to reevaluate the standards and regulations for artificial sweeteners. Conclusions: Through this study, we aimed to determine the content of aspartame and acesulfame-K contained in makgeolli currently distributed in South Korea and the safety of exposure to the human body when consumed.

키워드

과제정보

이 연구는 2023년 을지대학교 대학혁신지원사업 지원을 받아 진행한 연구임.

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