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A case of primary central nervous system lymphoma diagnosed with cerebrospinal fluid analysis: replacement brain biopsy with cerebrospinal fluid immunohistochemistry and immunoglobulin gene rearrangement

  • Lee, Jun Ho (Department of Neurology, Haeundae Paik Hospital, Inje University of College of Medicine) ;
  • Yu, Shinae (Department of Laboratory Medicine, Haeundae Paik Hospital, Inje University of College of Medicine) ;
  • Lee, Ja Young (Department of Laboratory Medicine, Busan Paik Hospital, Inje University of College of Medicine) ;
  • Kim, Yeon Mee (Department of Pathology, Haeundae Paik Hospital, Inje University of College of Medicine) ;
  • Lee, Dong Ah (Department of Neurology, Haeundae Paik Hospital, Inje University of College of Medicine) ;
  • Kim, Sung Eun (Department of Neurology, Haeundae Paik Hospital, Inje University of College of Medicine)
  • Received : 2022.04.28
  • Accepted : 2022.06.13
  • Published : 2022.10.30

Abstract

Primary central nervous system lymphoma (PCNSL) is a type of non-Hodgkin lymphoma confined to the central nervous system. Its diagnosis requires a stereotactic biopsy, which is an invasive procedure. Cerebrospinal fluid (CSF) analysis is less invasive and easier to perform than a stereotactic biopsy. We hereby report a PCNSL case diagnosed using CSF analysis and treated with systemic chemotherapy.

Keywords

References

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