Annals of Clinical Neurophysiology

The Korean Society of Clinical Neurophysiology (대한임상신경생리학회)
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Diffuse large B-cell lymphoma presenting as transverse myelitis

  • Zukhriddin, Urchiyev (Department of Medicine, School of Medicine, Jeonbuk National University) ;
  • Kang, Jin-Ju (Department of Neurology, Jeonbuk National University Hospital, Jeonbuk National University School of Medicine) ;
  • Jeong, Myoung-Ja (Research Institute of Clinical Medicine of Jeonbuk National University-Jeonbuk National University Hospital) ;
  • Oh, Sun-Young (Department of Neurology, Jeonbuk National University Hospital, Jeonbuk National University School of Medicine)
  • Received : 2022.07.11
  • Accepted : 2022.08.03
  • Published : 2022.10.30
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Abstract

Diffuse large B-cell lymphoma (DLBCL) is the most common type of non-Hodgkin's lymphoma. Although progressive lymphadenopathy is a typical feature, extranodal involvement may also occur, including the gastrointestinal tract, skin, bone, thyroid, and testes. Central nervous system invasion is rare, so differentiating it from diseases such as inflammatory demyelinating disorder or infection is essential. DLBCL is therefore a challenge to diagnose, especially when the first findings are neurological symptoms. We report an unusual case of DLBCL that presented as transverse myelitis.

Keywords

Acknowledgement

This work was supported by a National Research Foundation of Korea (NRF) grant funded by the Korean government (Ministry of Science and ICT) (No. 2022R1A2B5B01001933) and by the Biomedical Research Institute Fund, Jeonbuk National University Hospital.

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