Anatomy and Cell Biology

Korean Association of Anatomists (대한해부학회)
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A study on the correlation between spleen volume estimated via cavalieri principle on computed tomography images with basic hemogram and biochemical blood parameters

  • Necati Emre Sahin (Department of Anatomy, Faculty of Medicine, Karabuk University) ;
  • Zulal Oner (Department of Anatomy, Faculty of Medicine, Izmir Bakircay University) ;
  • Serkan Oner (Department of Radiology, Faculty of Medicine, Izmir Bakircay University) ;
  • Muhammed Kamil Turan (Department of Medical Biology, Faculty of Medicine, Karabuk University)
  • Received : 2021.09.01
  • Accepted : 2021.11.20
  • Published : 2022.03.31
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Abstract

Considering its hematological and immunological functions, spleen is a very important organ. A change occurs in its size as the spleen performs these functions. This study aims to examine the possible relationships between spleen volume and the basic hemogram and biochemical parameters in serum. Multidetector computed tomography images and basic hemogram and biochemical parameters of 74 adult individuals, 34 male and 40 female, who were found to be healthy, were used in the study. Spleen volume was estimated using the Cavalieri method on multidetector computed tomography images and the correlations between the volume value with basic hemogram and biochemistry parameters were researched. While negative significant correlations were found between the estimated spleen volume and lymphocyte percentage (r=-0.224) and platelet level (r=-0.271); positive significant correlations were found between hemoglobin level (r=0.228), hematocrit level (r=0.237), alanine aminotransferase (r=0.345), and erythrocyte level (r=0.375). As a result of this study, a relationship was found between spleen volume and lymphocyte percentage, hematocrit level, erythrocyte level, platelet level, and alanine aminotransferase level in serum. We believe that the results of the study will provide a larger perspective to clinicians in the diagnosis of diseases associated with spleen.

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References

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