Acknowledgement
This study was supported by the National Research Foundation of Korea (NRF) grant funded by the Korea government (MSIT) (2022R1F1A1069624).
References
- Siegel RL, Miller KD, Jemal A. Cancer statistics, 2016. CA Cancer J Clin 2016;66:7-30. https://doi.org/10.3322/caac.21332
- Almangush A, Bello IO, Keski-Santti H, Makinen LK, Kauppila JH, Pukkila M, et al. Depth of invasion, tumor budding, and worst pattern of invasion: prognostic indicators in early-stage oral tongue cancer. Head Neck 2014;36:811-8. https://doi.org/10.1002/hed.23380
- Calabrese L, Bizzoca ME, Grigolato R, Maffini FA, Tagliabue M, Negro R, et al. From bench to bedside in tongue muscle cancer invasion and back again: gross anatomy, microanatomy, surgical treatments and basic research. Life (Basel) 2020;10:197. https://doi.org/10.3390/life10090197
- Kamat M, Rai BD, Puranik RS, Datar UV. A comprehensive review of surgical margin in oral squamous cell carcinoma highlighting the significance of tumor-free surgical margins. J Cancer Res Ther 2019;15:449-54. https://doi.org/10.4103/jcrt.JCRT_273_17
- Matte BF, Kumar A, Placone JK, Zanella VG, Martins MD, Engler AJ, et al. Matrix stiffness mechanically conditions EMT and migratory behavior of oral squamous cell carcinoma. J Cell Sci 2019;132:jcs224360. https://doi.org/10.1242/jcs.224360
- Li Y, Bai S, Carroll W, Dayan D, Dort JC, Heller K, et al. Validation of the risk model: high-risk classification and tumor pattern of invasion predict outcome for patients with low-stage oral cavity squamous cell carcinoma. Head Neck Pathol 2013;7:211-23. https://doi.org/10.1007/s12105-012-0412-1
- Chatterjee D, Bansal V, Malik V, Bhagat R, Punia RS, Handa U, et al. Tumor budding and worse pattern of invasion can predict nodal metastasis in oral cancers and associated with poor survival in early-stage tumors. Ear Nose Throat J 2019;98:E112-9. https://doi.org/10.1177/0145561319848669
- Almangush A, Bello IO, Coletta RD, Makitie AA, Makinen LK, Kauppila JH, et al. For early-stage oral tongue cancer, depth of invasion and worst pattern of invasion are the strongest pathological predictors for locoregional recurrence and mortality. Virchows Arch 2015;467:39-46. https://doi.org/10.1007/s00428-015-1758-z
- Dillon JK, Brown CB, McDonald TM, Ludwig DC, Clark PJ, Leroux BG, et al. How does the close surgical margin impact recurrence and survival when treating oral squamous cell carcinoma? J Oral Maxillofac Surg 2015;73:1182-8. https://doi.org/10.1016/j.joms.2014.12.014
- Alicandri-Ciufelli M, Bonali M, Piccinini A, Marra L, Ghidini A, Cunsolo EM, et al. Surgical margins in head and neck squamous cell carcinoma: what is 'close'? Eur Arch Otorhinolaryngol 2013;270:2603-9. https://doi.org/10.1007/s00405-012-2317-8
- Bungum A, Jensen JS, Jakobsen KK, Christensen A, Gronhoj C, von Buchwald C. Impact of surgical resection margins less than 5mm in oral cavity squamous cell carcinoma: a systematic review. Acta Otolaryngol 2020;140:869-75. https://doi.org/10.1080/00016489.2020.1773532
- Zanoni DK, Migliacci JC, Xu B, Katabi N, Montero PH, Ganly I, et al. A proposal to redefine close surgical margins in squamous cell carcinoma of the oral tongue. JAMA Otolaryngol Head Neck Surg 2017;143:555-60. https://doi.org/10.1001/jamaoto.2016.4238
- Singh A, Mishra A, Singhvi H, Sharin F, Bal M, Laskar SG, et al. Optimum surgical margins in squamous cell carcinoma of the oral tongue: is the current definition adequate? Oral Oncol 2020;111:104938. https://doi.org/10.1016/j.oraloncology.2020.104938
- Lee DY, Kang SH, Kim JH, Kim MS, Oh KH, Woo JS, et al. Survival and recurrence of resectable tongue cancer: resection margin cutoff value by T classification. Head Neck 2018;40:283-91. https://doi.org/10.1002/hed.24944
- Jadhav KB, Gupta N. Clinicopathological prognostic implicators of oral squamous cell carcinoma: need to understand and revise. N Am J Med Sci 2013;5:671-9. https://doi.org/10.4103/1947-2714.123239
- Calabrese L, Bruschini R, Giugliano G, Ostuni A, Maffini F, Massaro MA, et al. Compartmental tongue surgery: long term oncologic results in the treatment of tongue cancer. Oral Oncol 2011;47:174-9. https://doi.org/10.1016/j.oraloncology.2010.12.006
- Pu Y, Ding L, Wang Y, Wang Y, Chen S, Huang X, et al. Biopsy pattern of invasion type to determine the surgical approach in earlystage oral squamous cell carcinoma. Virchows Arch 2021;479:109-19. https://doi.org/10.1007/s00428-020-03008-y