Clinical Nutrition Research

  • 제11권4호
  • /
  • Pages.277-288
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  • 2022
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  • 2287-3732(pISSN)
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  • 2287-3740(eISSN)
한국임상영양학회 (The Korean Society of Clinical Nutrition)
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The Association Between Dietary Acidity and Clinical Symptoms in Patients With Rheumatoid Arthritis

  • Arezoo Amjadi (Student Research Committee, School of Nutritional Sciences and Food Technology, Kermanshah University of Medical Sciences) ;
  • Yahya Pasdar (Research Center for Environmental Determinants of Health, Kermanshah University of Medical Sciences) ;
  • Shahab Rezaeian (Research Center for Environmental Determinants of Health, Kermanshah University of Medical Sciences) ;
  • Mostafa Nachvak (Research Center for Environmental Determinants of Health, Kermanshah University of Medical Sciences) ;
  • Saeid Ghavamzadeh (Food and Beverages Safety Research Center, Urmia University of Medical Sciences) ;
  • Mohammad Alizadeh (Food and Beverages Safety Research Center, Urmia University of Medical Sciences) ;
  • Hadi Abdollahzad (Food and Beverages Safety Research Center, Urmia University of Medical Sciences) ;
  • Jafar Navabi (School of Medicine, Kermanshah University of Medical Sciences)
  • 투고 : 2022.07.24
  • 심사 : 2022.10.24
  • 발행 : 2022.10.31
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초록

This study aimed to investigate the relationship between dietary acidity load and clinical symptoms in the patients with rheumatoid arthritis (RA). This case-control study examined 55 patients with RA and 215 healthy individuals in a Ravansar non-communicable diseases (RaNCDs) cohort study, Iran. Participants' food intakes were assessed using a validated food frequency questionnaire. The dietary acidity was calculated using potential renal acid load (PRAL), net endogenous acid production (NEAP), and dietary acid load (DAL) scores. The patients with RA were identified based on the self-reporting, medications history, and the approval of the cohort center physician following patients' examination. The odds ratio (OR) of joint stiffness in fully adjusted model was greater in the upper median of dietary acidity than in the lower median (PRAL: odds ratio [OR], 1.18; 95% confidence interval [CI], 0.59-2.36), but there was no statistically significant difference. The OR of joint pain in the upper median of dietary acidity was less than in the lower median in fully adjusted model (PRAL: OR, 0.70; 95% CI, 0.46-1.29), but the difference was not statistically significant. After adjusting potential confounders, people in the upper median of dietary acidity had a higher OR of developing RA than those in the lower median (PRAL: OR, 1.39; 95% CI, 0.70-2.76); however, it was not statistically significant. There was not any statistically significant relationship among dietary acidity and the odds of joint pain, joint stiffness, and developing RA.

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과제정보

The authors thank the PERSIAN Cohort Study collaborators and of Kermanshah University of medical sciences.

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