Journal of Oriental Neuropsychiatry (동의신경정신과학회지)

The Korean Society of Oriental Neuropsychiatry (대한한방신경정신과학회)
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Clinical Effects of Korean Medical Treatment on Depressive Disorder using Depression and Anxiety Scales

우울, 불안 척도를 통해 살펴본 우울증 환자에 대한 한의학적 치료 효과에 대한 연구

  • An, Yunyoung (Haneum Neuropsychiatry Clinic of Korean Medicine) ;
  • Kim, Lakhyung (Department of Neuropsychiatry, College of Korean Medicine, Woosuk University) ;
  • Yoo, Jongho (Haneum Neuropsychiatry Clinic of Korean Medicine)
  • 안윤영 (한음 한방신경정신과 한의원) ;
  • 김락형 (우석대학교 한의과대학 신경정신과학교실) ;
  • 유종호 (한음 한방신경정신과 한의원)
  • Received : 2022.08.25
  • Accepted : 2022.09.26
  • Published : 2022.09.30
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Abstract

Objectives: To examine clinical effects of Korean medical treatment on depressive disorder. Methods: Medical records of 102 patients diagnosed with depressive disorder who were treated with Korean medical treatment (herbal-medication, acupuncture, Korean psychotherapy) for at least 12 weeks and measured psychological scales (Beck Depression Inventory-II (BDI-II), State-Trait Anxiety Inventory (STAI), Beck Anxiety Inventory (BAI), and State-Trait Anger Expression Inventory (STAXI)) every 4 weeks were analyzed. Results: After 12 weeks of treatment, BDI-II, STAI-X-1/2, BAI, and STAXI-S/T all decreased statistically significantly. STAI-X-1 and BAI were significantly decreased throughout the treatment interval (comparisons every 4 weeks). The other four scales decreased significantly from 0 to 4 weeks and from 8 to 12 weeks. Conclusions: Treatment for depressive disorder with Korean Medicine was effective not only in improving overall symptoms of depressed patients, but also in improving accompanying anxiety, anger, and physical symptoms. In addition, since all scores were gradually decreased, continuous treatment would be important.

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References

  1. Korean Neuropsychiatry Association. Textbook of Neuropsychiatry. 3rd ed.. Seoul: iMiS Company; 2017:273-308, 711-20.
  2. Korean Ministry of Health and Welfare. The epidemiological survey of mental disorders in Korea 2021. Sejong; Korean Ministry of Health and Welfare:2021.
  3. Ko JI, Phee SS, Lyu MK, Oh SW, Park MC. Stress and Emotional Response in Patients with Mood Disorder. Journal of the Korean Society of Biological Therapies in Psychiatry. 1999;5(2):113-21.
  4. Fava M, Rosenbaum JF. Anger attacks in patients with depression. Journal of Clinical Psychiatry. 1999;60 suppl 15:21-4.
  5. Carvalho AF, Sharma MS, Brunoni AR, Vieta E, Fava GA. The Safety, Tolerability and Risks Associated with the Use of Newer Generation Antidepressant Drugs: A Critical Review of the Literature. Psychother Psychosom. 2016; 85(5):270-88. doi:10.1159/000447034.
  6. Segraves RT. Sexual Dysfunction Associated with Antidepressant Therapy. Urologic Clinics of North America. 2007;34(4):575-9. doi: 10.1016/j.ucl.2007.08.003.
  7. R Deshmukh , Franco K. Managing weight gain as a side effect of antidepressant therapy. Cleveland Clinic Journal of Medicine. 2003;70(7):614-23. doi: 10.3949/ccjm.70.7.614.
  8. Dubovicky M, Belovicova K, Csatlosova K, Bogi E. Risks of using SSRI / SNRI antidepressants during pregnancy and lactation. Interdiscip Toxicol. 2017;10(1):30-4. doi:10.1515/intox-2017-0004.
  9. Ploderl M, Hengartner MP. Antidepressant prescription rates and suicide attempt rates from 2004 to 2016 in a nationally representative sample of adolescents in the USA. Epidemiology and Psychiatric Sciences. 2019;28(5):589-91. doi:10.1017/S2045796018000136.
  10. Richardson K, Bennett K, Kenny RA. Polypharmacy including falls risk-increasing medications and subsequent falls in community-dwelling middle-aged and older adults. Age Ageing. 2015;44(1):90-6. doi:10.1093/ageing/afu141.
  11. The Textbook Compilation Committee of Neuropsychiatry of Korean Medical Schools in Nation. The Neuropsychiatry of Korean Medicine. 3rd ed.. Seoul: Jipmoon-Dang. 2018: 249-59.
  12. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders. 5th ed.. (Kwon JS, et al., Trans). Seoul: Hakjisa. 2017 (Original work published 2013):169-70.
  13. Li C, Huang B, Zhang YW. Chinese Herbal Medicine for the Treatment of Depression: Effects on the Neuroendocrine-Immune Network. Pharmaceuticals (Basel). 2021; 14(1):65. doi: 10.3390/ph14010065.
  14. Seung HB , Kwon HJ , Kim SH. Effectiveness and Safety of Traditional East Asian Herbal Medicine as Monotherapy for Major Depressive Disorder: A Systematic Review and Meta-Analysis. Journal of Oriental Neuropsychiatry 2022; 33(1):79-111. doi: 10.7231/JON.2022.33.1.079.
  15. Yeung WF, Chung KF, Ng KY, Yu YM, Zhang SP, Ng BFL, Ziea ETC. Prescription of Chinese herbal medicine in pattern-based traditional Chinese medicine treatment for depression: a systematic review. Evidence-Based Com - plementary and Alternative Medicine. 2015;2015:160189. doi: 10.1155/2015/160189.
  16. Kim JY, Kim H, Lee JY, Jung JH, Yang CS, Lee MY, Jung IC. A Prospective Observational Study of Herbal Medicines on Depressive Disorder. Journal of Oriental Neuropsychiatry. 2020;31(2):63-76. doi:10.7231/jon.2020.31.2.063.
  17. Korean Institute of Oriental Medicine. Korean Medicine Clinical Practice Guideline on Depression. Daejeon: Elsevier Korea L.L.C.; 2016.
  18. Sung HM, Kim JB, Park YN, Bai DS, Lee SH, Ahn HN. A Study on the Reliability and the Validity of Korean Version of the Beck Depression Inventory-II (BDI-II). Journal of the Korean Society of Biological Therapies in Psychiatry. 2008;14(2):201-12.
  19. Beck AT, Ward CH, Mendelson M, Mock J, Erbaugh J. An inventory for measuring depression. Archives of general psychiatry. 1961;4:561-71. doi: 10.1001/archpsyc.1961.01710120031004.
  20. Beck AT, Steer RA, Brown GK. Manual for the Beck Depression Inventory-II. 2nd ed.. San Antonio, TX : The Psychological Corporation;1996.
  21. Kim CY. Psychiatric Assessment Instruments. Seoul; Hanauihaksa.2010:120-3, 223-5.
  22. Beck AT, Epstein N, Brown G & Steer RA. An Inventory for measuring Clinical Anxiety: Psychometric Properties. Journal of Consulting and Clinical Psychology. 1988; 56(6):893-7. doi: 10.1037//0022-006x.56.6.893.
  23. Chun KK, Kim DY, Lee JS. Development of the STAXI-K:IV. Korean Journal of Art Therapy. 2000;7(1):33-50.
  24. Ahn TH, Goo BS, Kim GW. According to Depression Index, Difference of Response to Mental Stress and Effect to Aromatherapy. Journal of Oriental Neuropsychiatry. 2012;23(3):11-22. DOI : 10.7231/JON.2012.23.3.011.
  25. Hwang JY, Jeon IC, Lee SR. The Review for Studies of Aromatherapy, Relaxation Therapy and Exercise Therapy on Depression. Journal of Oriental Neuropsychiatry. 2011;22(4):1-10. https://doi.org/10.7231/JON.2011.22.4.001
  26. Park SA, Kim YS, Lee HW, Kim GC. Effect of Aroma Hand Massage on Sleep Disturbance and Depression in Hospitalized Elderly Patients. Journal of Physiology & Pathology in Korean Medicine. 2011;25(2):365-72.
  27. Chung CY, Kim DH. Are Anxiety and Depression Distinct? : Exploratory Factor Analysis of Zung's Self-Rating Anxiety and Depression Scales. Korean Journal of Biological Psychiatry. 2013;20(1):21-7.
  28. Wittchen HU, Kessler RC, Pfister H, Lieb M. Why do people with anxiety disorders become depressed? A prospective-longitudinal community study. Acta psychiatrica Scandinavica. Supplementum. 2000;(406):14-23.
  29. Yoo JY, Jang CY, Jeong HR, SHin YJ, Kim SJ, Lee UJ. Three Cases Report of Anxiety and Depression Disorder in the Traffic Accident Patients Treated with Prescription of Kami-shoyo-san. The Journal of Korean Oriental Internal Medicine. 2014;35(4):556-72.
  30. Wang Y, Shi YH, Xu Z, Fu H, Zeng H, Zheng GQ. Efficacy and safety of Chinese herbal medicine for depression: A systematic review and meta-analysis of randomized controlled trials. Journal of psychiatric research. 2019;117: 74-91. doi:10.1016/j.jpsychires.2019.07.003.