Korean Journal of Biological Psychiatry (생물정신의학)

The Korean Society of Biological Psychiatry (대한생물정신의학회)
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Alterations in Functions of Cognitive Emotion Regulation and Related Brain Regions in Maltreatment Victims

아동기 학대 경험이 인지적 정서조절 능력 및 관련 뇌영역 기능에 미치는 영향

  • Kim, Seungho (Department of Medical & Biological Engineering, Kyungpook National University) ;
  • Lee, Sang Won (Department of Psychiatry, Kyungpook National University Chilgok Hospital) ;
  • Chang, Yongmin (Department of Molecular Medicine, School of Medicine, Kyungpook National University) ;
  • Lee, Seung Jae (Department of Psychiatry, School of Medicine, Kyungpook National University)
  • 김승호 (경북대학교 의용생체공학과) ;
  • 이상원 (칠곡경북대학교병원 정신건강의학과) ;
  • 장용민 (경북대학교 의과대학 분자의학교실) ;
  • 이승재 (경북대학교 의과대학 정신건강의학교실)
  • Received : 2022.02.07
  • Accepted : 2022.03.31
  • Published : 2022.04.30
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Abstract

Objectives Maltreatment experiences can alter brain function related to emotion regulation, such as cognitive reappraisal. While dysregulation of emotion is an important risk factor to mental health problems in maltreated people, studies reported alterations in brain networks related to cognitive reappraisal are still lacking. Methods Twenty-seven healthy subjects were recruited in this study. The maltreatment experiences and positive reappraisal abilities were measured using the Childhood Trauma Questionnaire-Short Form and the Cognitive Emotion Regulation Questionnaire, respectively. Twelve subjects reported one or more moderate maltreatment experiences. Subjects were re-exposed to pictures after the cognitive reappraisal task using the International Affective Picture System during fMRI scan. Results The maltreatment group reported more negative feelings on negative pictures which tried cognitive reappraisal than the no-maltreatment group (p < 0.05). Activities in the right superior marginal gyrus and right middle temporal gyrus were higher in the maltreatment group (uncorrected p < 0.001, cluster size > 20). Conclusions We found that paradoxical activities in semantic networks were shown in the victims of maltreatment. Further study might be needed to clarify these aberrant functions in semantic networks related to maltreatment experiences.

Keywords

Acknowledgement

This work was supported by the National Research Foundation of Korea (NRF) grant funded by the Korea government (MSIT) (No. 2021R1F1A1049460).

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