Herbal Formula Science (대한한의학방제학회지)

The Korean Medicine Society for the Herbal Formula Study (대한한의학방제학회)
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The application of recent taste theory in physiology for the Kimi theory of the 『ShinNongBonChoKyung(Divine Farmer's Classic of Materia Medica)』.

현대 생리학적 미각(味覺) 이론을 통한 『신농본초경(神農本草經)』 기미론(氣味論)의 재해석

  • Received : 2022.08.21
  • Accepted : 2022.08.28
  • Published : 2022.08.31
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Abstract

Objects : Recent taste theory has been advanced to the receptor and cell of taste. We tried to apply the taste theory to the Kimi theory (氣味論) of 『ShinNongBonChoKyung (神農本草經)』 for the purpose of resonance between the Kimi theory and the taste theory. Methods : The special issues in Current Opinion in Physiology of the year 2021 gave us much information. Based on it, we have searched for more papers using google scholars with the key words; taste, taste receptor, sweet, umami, bitter, salty, sour. Then, we analyzed and compared the Kimi theory of 『ShinNong BonChoKyung)』 with the research papers of physiological taste. Results : Three classification of the herbs in 『ShinNongBonChoKyung』 is very reasonable based on the Taste theory. There is umami and no spicy in the taste theory, and Sweet includes umami in the Kimi theory. Taste is such a complex and connective sensory reaction of the brain and body of human being. There are much more results to couple the Kimi with the taste theory. Conclusions : The pharmacological property of Kimi theory of 『ShinNongBonCho Kyung』 will help the taste theory much more develop and expand. In addition to qi(氣), the Kimi theory will also find a way to be in harmony with modern pharmacology in the respective of taste(味) with the help of taste theory.

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References

  1. Ahn S-W. The systematic of medicinal herb books and the development history of medicinal herb study. Korean Journal of Oriental Medicine. 2005;11(1):19-32.
  2. Lee S-H. A Study on Xu Dachun's Understanding of Medicinals According to the Shennong Bencao Baizhonglu. Journal of Korean Medical classics. 2021;34(4):95-117. https://doi.org/10.14369/JKMC.2021.34.4.095
  3. Kim I. A study on the literal research kimi-theory. Korean Journal of Oriental Medicine. 1997;3(1):169-81.
  4. Kim M. A new-approach of food function by Qi-taste theory: Nambu; 2018.
  5. Lee TH. Brief Review on the Standard of the Taste and Property -centered on the Mahwang, Gyeji, Jagyak. Herbal Formula Science 2018;26(2):123-7. https://doi.org/10.14374/HFS.2018.26.2.123
  6. Boughter Jr JD, Fletcher M. Rethinking the role of taste processing in insular cortex and forebrain circuits. Current Opinion in Physiology. 2021;20:52-6. https://doi.org/10.1016/j.cophys.2020.12.009
  7. Ye M-K. Physiology of Olfaction and Gustation: Focused on Receptor Cells. J Clinical Otolaryngol. 2020;31(2):133-8.
  8. Chandrashekar J, Hoon MA, Ryba NJ, Zuker CS. The receptors and cells for mammalian taste. Nature. 2006;444(7117):288-94. https://doi.org/10.1038/nature05401
  9. Ohla K. Flexible and dynamic representations of gustatory information. Current Opinion in Physiology. 2021;20:140-5. https://doi.org/10.1016/j.cophys.2021.01.002
  10. Huang AY. Immune gustatory processing: immune responses to drugs shape peripheral taste signals. Current Opinion in Physiology. 2021;20:112-7. https://doi.org/10.1016/j.cophys.2021.01.007
  11. Adler E, Hoon MA, Mueller KL, Chandrashekar J, Ryba NJ, Zuker CS. A novel family of mammalian taste receptors. Cell. 2000;100(6):693-702. https://doi.org/10.1016/S0092-8674(00)80705-9
  12. Mattes RD. Taste, teleology and macronutrient intake. Current Opinion in Physiology. 2021;19:162-7. https://doi.org/10.1016/j.cophys.2020.11.003
  13. Di Lorenzo PM. Taste in the brain is encoded by sensorimotor state changes. Current Opinion in Physiology. 2021;20:39-45. https://doi.org/10.1016/j.cophys.2020.12.003
  14. Chandrashekar J, Mueller KL, Hoon MA, Adler E, Feng L, Guo W, et al. T2Rs function as bitter taste receptors. Cell. 2000;100(6):703-11. https://doi.org/10.1016/S0092-8674(00)80706-0
  15. Yarmolinsky DA, Zuker CS, Ryba NJ. Common sense about taste: from mammals to insects. Cell. 2009;139(2):234-44. https://doi.org/10.1016/j.cell.2009.10.001
  16. Nelson G, Hoon MA, Chandrashekar J, Zhang Y, Ryba NJ, Zuker CS. Mammalian sweet taste receptors. Cell. 2001;106(3):381-90. https://doi.org/10.1016/S0092-8674(01)00451-2
  17. Nelson G, Chandrashekar J, Hoon MA, Feng L, Zhao G, Ryba NJ, et al. An amino-acid taste receptor. Nature. 2002;416(6877):199-202. https://doi.org/10.1038/nature726
  18. Zhao GQ, Zhang Y, Hoon MA, Chandrashekar J, Erlenbach I, Ryba NJ, et al. The receptors for mammalian sweet and umami taste. Cell. 2003;115(3):255-66. https://doi.org/10.1016/S0092-8674(03)00844-4
  19. Mueller KL, Hoon MA, Erlenbach I, Chandrashekar J, Zuker CS, Ryba NJ. The receptors and coding logic for bitter taste. Nature. 2005;434(7030):225-9. https://doi.org/10.1038/nature03352
  20. Barretto RP, Gillis-Smith S, Chandrashekar J, Yarmolinsky DA, Schnitzer MJ, Ryba NJ, et al. The neural representation of taste quality at the periphery. Nature. 2015;517(7534):373-6. https://doi.org/10.1038/nature13873
  21. Finger TE, Barlow LA. Cellular diversity and regeneration in taste buds. Current opinion in physiology. 2021;20:146-53. https://doi.org/10.1016/j.cophys.2021.01.003
  22. Banik DD, Medler KF. Bitter, sweet, and umami signaling in taste cells: it's not as simple as we thought. Current Opinion in Physiology. 2021;20:159-64. https://doi.org/10.1016/j.cophys.2021.01.010
  23. Liman ER, Kinnamon SC. Sour taste: receptors, cells and circuits. Current Opinion in Physiology. 2021;20:8-15. https://doi.org/10.1016/j.cophys.2020.12.006
  24. Roper SD. Chemical and electrical synaptic interactions among taste bud cells. Current opinion in physiology. 2021;20:118-25. https://doi.org/10.1016/j.cophys.2020.12.004
  25. An SS, Liggett SB. Taste and smell GPCRs in the lung: evidence for a previously unrecognized widespread chemosensory system. Cellular signalling. 2018;41:82-8. https://doi.org/10.1016/j.cellsig.2017.02.002
  26. Bigiani A. The origin of saltiness: oral detection of NaCl. Current Opinion in Physiology. 2021;19:156-61. https://doi.org/10.1016/j.cophys.2020.11.006
  27. Huang AL, Chen X, Hoon MA, Chandrashekar J, Guo W, Trankner D, et al. The cells and logic for mammalian sour taste detection. Nature. 2006;442(7105):934-8. https://doi.org/10.1038/nature05084
  28. Ye M-K. Gustatory Neural Coding. Korean J Otolaryngol 2005;48(9):1074-80.
  29. Wang L, Gillis-Smith S, Peng Y, Zhang J, Chen X, Salzman CD, et al. The coding of valence and identity in the mammalian taste system. Nature. 2018;558(7708):127-31. https://doi.org/10.1038/s41586-018-0165-4
  30. Yoshida R, Yasumatsu K, Ninomiya Y. The sweet taste receptor, glucose transporters, and the ATP-sensitive K+ (KATP) channel: sugar sensing for the regulation of energy homeostasis. Current Opinion in Physiology. 2021;20:57-63. https://doi.org/10.1016/j.cophys.2021.01.009
  31. Margolskee RF, Dyer J, Kokrashvili Z, Salmon KSH, Ilegems E, Daly K, et al. T1R3 and gustducin in gut sense sugars to regulate expression of Na+-glucose cotransporter 1. Proceedings of the National Academy of Sciences. 2007;104(38):15075-80. https://doi.org/10.1073/pnas.0706678104
  32. Tan H-E, Sisti AC, Jin H, Vignovich M, Villavicencio M, Tsang KS, et al. The gut-brain axis mediates sugar preference. Nature. 2020;580(7804):511-6. https://doi.org/10.1038/s41586-020-2199-7
  33. Project CT. Shen Nong Ben Cao Jing (Divine Farmer's Classic of Materia Medica: https://ctext.org/wiki.pl?if=gb&chapter=10407;2022
  34. Rhyu M. The science behind tastes: Korea Food Research Institute; 2015.