한국환경보건학회지 (Journal of Environmental Health Sciences)

  • 제48권4호
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  • Pages.206-215
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  • 2022
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  • 1738-4087(pISSN)
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  • 2233-8616(eISSN)
한국환경보건학회 (Korean Society of Environmental Health)
권호 표지
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생활화학제품의 알레르기반응가능 향료성분 함유 현황 및 동시 출현 패턴 조사

Characteristics and Co-Occurrence Patterns of Fragrance Allergens in Consumer Chemical Products

  • 김수민 (서울대학교 보건대학원 환경보건학과) ;
  • 이기영 (서울대학교 보건대학원 환경보건학과) ;
  • 임미영 (서울대학교 보건환경연구소)
  • Kim, Soomin (Department of Environmental Health Sciences, Graduate School of Public Health, Seoul National University) ;
  • Lee, Kiyoung (Department of Environmental Health Sciences, Graduate School of Public Health, Seoul National University) ;
  • Lim, Miyoung (Institute of Health and Environment, Seoul National University)
  • 투고 : 2022.07.01
  • 심사 : 2022.08.09
  • 발행 : 2022.08.31
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초록

Background: Fragrance substances in consumer products can cause adverse health effects such as contact allergy. In South Korea, consumer chemical products must list 26 known fragrance allergens on product labels when they contain more than 0.01%. Fragrance substances are mostly used in combination, so co-exposure can occur via use of a consumer chemical product. Co-exposure to fragrance allergens may show a synergistic effect on the human body. Objectives: The aims of the study were to analyze the characteristics of fragrance allergens in consumer chemical products available on public websites and to identify the co-occurrence patterns of fragrance allergens. Methods: The chemicals in 1,443 ingredient disclosures for consumer chemical products were collected through the Ecolife database. The 26 labelled fragrance allergens were identified by category of consumer chemical product. The co-occurrence patterns of the 26 labelled fragrance allergens were analyzed by frequent pattern mining. The unlabelled fragrance allergens presented by European Union Scientific Committee on Consumer Safety were also identified. Results: Consumer chemical products contained an average of 5.3±4.2 substances among the 26 labelled fragrance allergens. More than 85% of air fresheners, deodorizing agents, and fabric softeners contained at least one of the 26 labelled fragrance allergens. The most frequently contained fragrance allergens were limonene (50.5%), linalool (49.9%), hexyl cinnamal (34.0%), and citronellol (28.3%). 16.7% of consumer chemical products showed a co-occurrence of limonene, linalool, hexyl cinnamal, and citronellol. Thirty-eight unlabelled fragrance allergens were found in the consumer chemical products, with hexamethylindanopyran (25.2%) being the most frequently contained substance. Conclusions: The characteristics and co-occurrence patterns of 26 labelled fragrance allergens would be useful information for the management of co-exposure to fragrance allergens in consumer chemical products. It is necessary for attention to be paid to unlabelled fragrance allergens.

키워드

과제정보

본 연구는 환경부의 재원으로 한국환경산업기술원의 생활화학제품 안전관리 기술개발사업의 지원을 받아 연구되었습니다(과제번호: 2021002970003, NTIS: 1485017937).

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