Clinical Endoscopy

The Korean Society of Gastrointestinal Endoscopy (대한소화기내시경학회)
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Comparison between a novel core knife and the conventional IT knife 2 for endoscopic submucosal dissection of gastric mucosal lesions

  • Myeongsoon Park (Division of Gastroenterology, Department of Internal Medicine, Keimyung University Dongsan Medical Center, Keimyung University School of Medicine) ;
  • Jin Wook Lee (Division of Gastroenterology, Department of Internal Medicine, Keimyung University Dongsan Medical Center, Keimyung University School of Medicine) ;
  • Dong Woo Shin (Division of Gastroenterology, Department of Internal Medicine, Keimyung University Dongsan Medical Center, Keimyung University School of Medicine) ;
  • Jungseok Kim (Division of Gastroenterology, Department of Internal Medicine, Keimyung University Dongsan Medical Center, Keimyung University School of Medicine) ;
  • Yoo Jin Lee (Division of Gastroenterology, Department of Internal Medicine, Keimyung University Dongsan Medical Center, Keimyung University School of Medicine) ;
  • Ju Yup Lee (Division of Gastroenterology, Department of Internal Medicine, Keimyung University Dongsan Medical Center, Keimyung University School of Medicine) ;
  • Kwang Bum Cho (Division of Gastroenterology, Department of Internal Medicine, Keimyung University Dongsan Medical Center, Keimyung University School of Medicine)
  • Received : 2021.11.22
  • Accepted : 2022.03.10
  • Published : 2022.11.30
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Abstract

Background/Aims: Few studies have compared the performances of endoscopic knives. This study aimed to compare the therapeutic outcomes of a novel core knife and the conventional IT knife 2 for endoscopic submucosal dissection (ESD) of gastric mucosal lesions. Methods: This prospective, non-inferiority trial included patients diagnosed with gastric adenoma or early-stage adenocarcinoma at Keimyung University Dongsan Hospital between June and November 2020. The patients were randomly assigned to either the core knife or the IT knife 2 group. The operators and assistants scored the knives' grip convenience and cutting abilities. Results: A total of 39 patients were enrolled (core knife group, 20 patients; IT knife 2 group, 19 patients). There were no significant between-group differences in operator-assessed grip convenience (9.600 vs. 9.526, p=0.753), cutting ability (9.600 vs. 9.105, p=0.158), or assistant-assessed grip convenience (9.500 vs. 9.368, p=0.574). Conclusions: The core knife achieved therapeutic outcomes that were comparable to those of the IT knife 2 for ESD of gastric mucosal lesions.

Keywords

Acknowledgement

This work was supported by the supporting project to evaluate new domestic medical devices in hospitals funded by the Korea Health Industry Development Institute (KHIDI) and INCORE Co. Ltd (Daegu, Korea).

References

  1. Bray F, Ferlay J, Soerjomataram I, et al. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin 2018;68:394-424.
  2. Korean Statistical Information Service. Causes of Death Statistics in Korea 2019 [Internet]. Daejeon: Korean Statistical Information Service; 2020 [cited 2020 Sep 21]. Available from: http://kostat.go.kr/portal/korea/kor_nw/1/1/index.board? bmode=download&bSeq=&aSeq=385219&ord=2.
  3. Park CH, Yang DH, Kim JW, et al. Clinical practice guideline for endoscopic resection of early gastrointestinal cancer. Clin Endosc 2020;53:142-166.
  4. Ko BM. History and development of accessories for endoscopic submucosal dissection. Clin Endosc 2017;50:219-223.
  5. Song JH, Kim SG. Endoscopic submucosal dissection for gastric neoplasia. In: Chun HJ, Yang SK, Choi MG, editors. Therapeutic gastrointestinal endoscopy: a comprehensive atlas. Singapore: Springer; 2019. p. 125-141.
  6. Sumiyama K, Tajiri H. History of ESD. In: Fukami N, editor. Endoscopic submucosal dissection: principles and practice. New York: Springer; 2015. p. 3-8.
  7. Gotoda T, Iwasaki M, Kusano C, et al. Endoscopic resection of early gastric cancer treated by guideline and expanded National Cancer Centre criteria. Br J Surg 2010;97:868-871.
  8. Kamiya S, Rouvelas I, Lindblad M, et al. Current trends in gastric cancer treatment in Europe. J Cancer Metastasis Treat 2018;4:35.
  9. Draganov PV, Wang AY, Othman MO, et al. AGA Institute Clinical Practice Update: endoscopic submucosal dissection in the United States. Clin Gastroenterol Hepatol 2019;17:16-25.
  10. Fukami N. Endoscopic submucosal dissection: principles and practice. New York: Springer; 2015.
  11. Oda I, Suzuki H, Nonaka S, et al. Complications of gastric endoscopic submucosal dissection. Dig Endosc 2013;25(Suppl 1):71-78.
  12. Choi HS, Chun HJ. Accessory devices frequently used for endoscopic submucosal dissection. Clin Endosc 2017;50:224-233.
  13. Fukami N. Appendix: commonly used ESD knives. In: Fukami N, editor. Endoscopic submucosal dissection: principles and practice. New York: Springer; 2015. p. 257-260.
  14. Hosokawa K, Yoshida S. Recent advances in endoscopic mucosal resection for early gastric cancer. Gan To Kagaku Ryoho 1998;25:476-483.
  15. Cho JY, Cho WY. The current status of endoscopic submucosal dissection. Korean J Gastrointest Endosc 2008;37:317-320.
  16. Konuma H, Matsumoto K, Ueyama H, et al. Procedure time for gastric endoscopic submucosal dissection according to location, considering both mucosal circumferential incision and submucosal dissection. Gastroenterol Res Pract 2016;2016:9183793.
  17. Kim KO, Kim SJ, Kim TH, et al. Do you have what it takes for challenging endoscopic submucosal dissection cases? World J Gastroenterol 2011;17:3580-3584.
  18. Lee SG, Cho KB, Hong YS, et al. Nonsurgical treatment of gastric perforation complicated by endoscopic mucosal resection and endoscopic submucosal dissection. Korean J Gastrointest Endosc 2008;37:97-104.
  19. Park YS, Park SW, Song SY, et al. Endoscopic mucosal resection using insulated-tip electrosurgical knife. Korean J Gastrointest Endosc 2003;26:397-404.