The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology (한방안이비인후피부과학회지)

The Society of Korean Medicine Ophthalmology, Otolaryngology & Dermatology (대한한방안이비인후피부과학회)
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A Review on the of External Ointment Treatment for Diabetic Foot Ulcer

당뇨병성 족부 궤양의 외용 연고 처치에 대한 고찰

  • Jeong, Mi-rae (Dept. of Ophthalmology, Otolaryngology and Dermatology, Pusan National University Korean Medicine Hospital) ;
  • Heo, Eun-na (Dept. of Ophthalmology, Otolaryngology and Dermatology, Pusan National University Korean Medicine Hospital) ;
  • Kim, Chul-yun (Saengki Korean Medicine Clinic) ;
  • Kwon, kang (Dept. of Ophthalmology, Otolaryngology and Dermatology, Pusan National University Korean Medicine Hospital) ;
  • Seo, Hyung-sik (Dept. of Ophthalmology, Otolaryngology and Dermatology, Pusan National University Korean Medicine Hospital)
  • 정미래 (부산대학교 한방병원 안이비인후피부과) ;
  • 허은나 (부산대학교 한방병원 안이비인후피부과) ;
  • 김철윤 (생기한의원) ;
  • 권강 (부산대학교 한방병원 안이비인후피부과) ;
  • 서형식 (부산대학교 한방병원 안이비인후피부과)
  • Received : 2022.06.27
  • Accepted : 2022.08.16
  • Published : 2022.08.25
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Abstract

Objectives : Diabetic Foot Ulcer(DFU) is one of the common complications of diabetes. DFU is difficult to treat compared to other chronic wounds and clinically effective treatments are limited. The purpose of this study is to review the of external ointment treatment for DFU. Methods : 8 databases such as PubMed, EMBASE, CENTRAL, CNKI, NDSL, RISS, KISS, OASIS including English, Korean and Chinese were searched by structured search strategies that consist of terms as 'diabetic foot', 'diabetic foot ulcer(DFU)' and 'randomized' from January 2001 to January 2021. All randomized controlled trials(RCTs) involving treatment group as external ointment or in combination with conventional treatment were included. Results: A total of 20 RCTs was identified and analyzed. In treatment group, ointment was applied based on conventional treatment. A total of 16 different ointments were used, and the frequency of use was highest in the order of Heat-clearing drug, Blood-activating and stasis-dispelling drug, Tonifying and Replenishing drug and Orifice-opening drug. The most used herbs were in the order of Coptis chinensis Franch., Phellodendron chinense Schneid., Borneolum syntheticum., Angelica sinensis(Oliv.) Diels. In treatment group, a clinically effective effect was obtained compared to the contrast group. Conclusions : The result of this study suggest that external ointment treatment based on conventional treatment can be applied to DFU.

Keywords

Acknowledgement

본 연구는 2022년도 부산대학교병원 임상연구비 지원으로 이루어 졌음.

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