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Changes of Microorganisms and Active Compounds in Glycyrrhizae Radix as Affected by Drying Method and Gamma Ray Treatments

건조 방법 및 감마선 조사에 따른 감초의 미생물 저감효과 및 유효성분 변화

  • Kim, Joon-Hee (Medicinal Herb Research Team, National Development Institute of Korean Medicine) ;
  • Kang, Byoung-Man (Medicinal Herb Research Team, National Development Institute of Korean Medicine) ;
  • Kim, Jun Yong (Medicinal Herb Research Team, National Development Institute of Korean Medicine) ;
  • Kim, Ryu-Dam (Medicinal Herb Research Team, National Development Institute of Korean Medicine) ;
  • Hwang, Hyun Chul (Medicinal Herb Research Team, National Development Institute of Korean Medicine) ;
  • Lee, Jae-Woong (Medicinal Herb Research Team, National Development Institute of Korean Medicine)
  • 김준희 (한국한의약진흥원 한약재육성팀) ;
  • 강병만 (한국한의약진흥원 한약재육성팀) ;
  • 김준용 (한국한의약진흥원 한약재육성팀) ;
  • 김류담 (한국한의약진흥원 한약재육성팀) ;
  • 황현철 (한국한의약진흥원 한약재육성팀) ;
  • 이재웅 (한국한의약진흥원 한약재육성팀)
  • Received : 2022.02.15
  • Accepted : 2022.05.11
  • Published : 2022.08.01

Abstract

Glycyrrhizae Radix is an herbal medicine vulnerable to fungi. So there are regulations on mycotoxins. Therefore, in this study, the affect of various drying methods and additional gamma irradiation (10 kGy) was studied to suppress the microbial generation of Glycyrrhizae Radix. As a result of detecting and comparing microorganisms using the dry film method for samples prepared by each of natural, hot air, freezing, microwave drying and gamma irradiation, the affect of reducing microorganisms by microwave drying and gamma irradiation was confirmed. There was no statistically significant change in the content of the active compounds between the treatment groups.

감초의 건조 방법 및 감마선 조사를 이용하여 미생물 저감화 효과를 확인하였다. 또한 감마선 조사 때문에 성분 변화가 있는지 확인하기 위해서 HPLC를 이용하여 유효성분인 Glycyrrhizin, Liquiritin의 성분 변화를 확인하였다. 건조 방법으로는 마이크로웨이브 건조, 동결건조, 열풍건조, 자연건조 순으로 미생물 저감화에 효과적이었고, 감마선 조사 후에는 모든 건조 시료에서 미생물이 사멸되었음을 확인하였으며, 감마선 조사에 따른 유효성분 함량의 수치 변화는 있었으나 통계적으로 유의성이 없게 나타났다.

Keywords

References

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