Journal of Microbiology and Biotechnology

  • 제32권5호
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  • Pages.594-601
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  • 2022
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  • 1017-7825(pISSN)
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  • 1738-8872(eISSN)
한국미생물·생명공학회 (The Korean Society for Microbiology and Biotechnology)
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Evaluation of the EtOAc Extract of Lemongrass (Cymbopogon citratus) as a Potential Skincare Cosmetic Material for Acne Vulgaris

  • Kim, Chowon (Department of Food Science and Nutrition, College of Human Ecology, Pusan National University) ;
  • Park, Jumin (Department of Food Science and Nutrition, College of Human Ecology, Pusan National University) ;
  • Lee, Hyeyoung (Division of Applied Bioengineering, Dong-Eui University) ;
  • Hwang, Dae-Youn (Department of Biomaterials Science, Pusan National University) ;
  • Park, So Hae (Department of Biomaterials Science, Pusan National University) ;
  • Lee, Heeseob (Department of Food Science and Nutrition, College of Human Ecology, Pusan National University)
  • 투고 : 2022.01.28
  • 심사 : 2022.04.18
  • 발행 : 2022.05.28
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초록

This study evaluated the biological properties of lemongrass (Cymbopogon citratus) extracts. The EtOAc extract of lemongrass had DPPH, TEAC, and nitric oxide-scavenging activity assay results of 58.06, 44.14, and 41.08% at the concentration of 50, 10, and 50 ㎍/ml, respectively. The EtOAc extract had higher elastase and collagenase inhibitory activities than the 80% MeOH, n-hexane, BuOH, and water extracts and comparable whitening activity toward monophenolase or diphenolase. Also, the EtOAc fraction had higher lipase inhibitory and antimicrobial activities against Cutibacterium acnes among extracts which is known to an important contributor to the progression of inflammatory acne vulgaris, and an opportunistic pathogen present in human skin. Total phenolic and flavonoid concentrations in the EtOAc extract were 132.31 mg CAE/g extract and 104.50 mg NE/g extract, respectively. Biologically active compounds in lemongrass extracts were analyzed by LC-MS. This study confirms that lemongrass extracts have potential use as cosmetic skincare ingredients. Thus, lemongrass can be considered a promising natural source of readily available, low-cost extracts rich in antioxidant, skincare, and antimicrobial compounds that might be suitable for replacing synthetic compounds in the cosmeceutical industry.

키워드

과제정보

This work was supported by the BK21 FOUR Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education, Korea (Grant number F21YY8109033).

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