Journal of Korean Medicine for Obesity Research (한방비만학회지)

The Society of Korean Medicine for obesity Research (한방비만학회)
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Comparison of Phytochemical Constituents According to the Cultivation Method (Paddy Field Cultivation, Upland Field Cultivation) of Korean Fresh Ginseng

한국산 수삼의 재배환경(논, 밭)에 따른 식물화학성분 비교

  • Her, Jae Young (Department of Oriental Medical Food & Nutrition, Semyung University) ;
  • Kim, Do Hyeong (Department of Oriental Medical Food & Nutrition, Semyung University) ;
  • Hwang, Yu Jin (Department of Oriental Medical Food & Nutrition, Semyung University) ;
  • Ko, Sung Kwon (Department of Oriental Medical Food & Nutrition, Semyung University) ;
  • Yang, Byung Wook (School of Industrial Bio-Pharmaceutical Science, Semyung University)
  • 허재영 (세명대학교 한방식품영양학과) ;
  • 김도형 (세명대학교 한방식품영양학과) ;
  • 황유진 (세명대학교 한방식품영양학과) ;
  • 고성권 (세명대학교 한방식품영양학과) ;
  • 양병욱 (세명대학교 바이오제약산업학부)
  • Received : 2022.05.05
  • Accepted : 2022.06.11
  • Published : 2022.06.30
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Abstract

Objectives: This study aimed to examine the changes in ingredients according to its cultivation method by examining the content of saponin and non-saponin components of ginseng. Methods: Ginseng saponin component analysis was compared and reviewed using the high-performance liquid chromatography method, and acidic polysaccharide component was measured using the carbazole sulfuric acid method. Results: The comparative analysis of ginseng saponin content of 4 and 6 years old fresh ginseng showed the following results. According to the cultivation method, upland field cultivation fresh ginseng showed higher average content of crude saponin than paddy field cultivation fresh ginseng. Whereas, paddy field cultivation fresh ginseng showed higher average content of total saponin than upland field cultivation fresh ginseng. Ginsenoside Rb1 showed higher content of paddy field cultivation fresh ginseng than upland field cultivation fresh ginseng in 6 years old ginseng. However, it showed higher content of upland field cultivation fresh ginseng than paddy field cultivation fresh ginseng in 4 years old ginseng. Additionally, ginsenoside Rg1 showed higher content of paddy field cultivation fresh ginseng than upland field cultivation fresh ginseng in 6 years old ginseng, whereas upland field cultivation fresh ginseng showed higher content of paddy field cultivation fresh ginseng in 4 years old ginseng. The effect on the content of ginseng saponins and acidic polysaccharides according to paddy field and upland field cultivation methods is considered to be small. Conclusions: The paddy field cultivation method, which is more efficient in production cost due to depletion of farmland and long-distance cultivation, is considered to be an economical cultivation method.

Keywords

Acknowledgement

본 연구는 농림축산식품부 미래형혁신식품기술개발사업(No. 119023-3)의 지원에 의해 이루어진 것임.

References

  1. Namba T. The Encyclopedia of Wakan-Yaku with color pictures (I). Hoikusha Publishing Company, Osaka : Hoikusha Publishing Company.. 1980 : 1-5.
  2. Sanata S, Kondo N, Shoji J, Tanaka O, Shibata S. Studies on the saponins of ginseng. I. Structure of ginsenoside-R0, Rb1, Rb2, Rc and Rd. Chem Pharm Bull. 1974 ; 22(3) : 421-8. https://doi.org/10.1248/cpb.22.421
  3. Yokozawa T, Kobayashi T, Oura H, Kawashima Y. Studies on the mechanism of the hypoglycemic activity of ginsenoside-Rb2 in streptozotocin-diabetic rats. Chem Pharm Bull. 1985 ; 33(2) : 869-72. https://doi.org/10.1248/cpb.33.869
  4. Mochizuki M, Yoo YC, Matsuzawa K, Sato K, Saiki I, Tonooka S, et al. Inhibitory effect of tumor metastasis in mice by saponins, ginsenoside-Rb2, 20(R)- and 20(S)-ginsenoside- Rg3, of red ginseng. Biol Pharm Bull. 1995 ; 18(9) : 1197-202. https://doi.org/10.1248/bpb.18.1197
  5. Matsuda H, Samukawa K, Kubo M. Anti-hepatitic activity of ginsenoside Ro. Planta Med. 1991 ; 57(6) : 523-6. https://doi.org/10.1055/s-2006-960198
  6. Jeong CS, Hyun JE, Kim YS. Anti-oxidative effect of ginsenoside Rb1 on the HCl. ethanol-induced gastric tissue in rats. Korean J Pharmacogn. 2002 ; 33(3) : 252-6.
  7. Jung IS, Cho YD. Effect of ginseng saponin fraction on absorption of cholesterol and serum lipid components. Korean J Ginseng Sci. 1985 ; 9(2) : 232-9.
  8. Yoon SH, Joo CN. Study on the preventive effect of ginsenosides against hypercholesterolemia and its mechanism. Korean J Ginseng Sci. 1993 ; 17(1) : 1-12.
  9. Wang BX, Cui JC, Liu A J, Wu SK. Studies on the anti-fatigue effect of the saponins of stems and leaves of Panax ginseng (SSLG). J Tradit Chin Med. 1983 ; 3(2) : 89-94.
  10. Saito H, Yoshida Y, Tagaki K. Effects of Panax ginseng root on exhaustive exercise in mice. Jpn J Pharmacol. 1974 ; 24(1) : 119-26. https://doi.org/10.1016/S0021-5198(19)32112-2
  11. Matsuda H, Samukawa K, Kubo M. Anti-inflammatory activity of ginsenoside Ro. Planta Med. 1990 ; 56(1) : 19-23. https://doi.org/10.1055/s-2006-960875
  12. Park JD. Recent studies on the chemical constituents of Korean Ginseng (Panax ginseng C.A. Meyer). Korean J Ginseng Sci. 1996 ; 20(4) : 389-415.
  13. Shin JY, Song JY, Yun YS, Yang HO, Rhee DK, Pyo S. Immunositimulating effects of acidic polysaccharides extract of Panax ginseng on macrophage function. Immunopharmacol Immunotoxicol. 2002 ; 24(3) : 469-82. https://doi.org/10.1081/IPH-120014730
  14. Sonoda Y, Kasahara T, Mukaida N, Shimizu N, Tomoda M, Takeda T. Stimulation of interleukin-8 production by acidic polysaccharides from the root of Panax ginseng. Immunopharmacology. 1998 ; 38(3) : 287-94. https://doi.org/10.1016/S0162-3109(97)00091-X
  15. Lee JH, Park EK, Uhm CS, Chung MS, Kim KH. Inhibition of Helicobacter pylori adhesion to human gastric adenocarcinoma epithelial cells by acidic polysaccharides from Artemisia capillaris and Panax ginseng. Planta Med. 2004 ; 70(7) : 615-9. https://doi.org/10.1055/s-2004-827183
  16. Shin HJ, Kim YS, Kwak YS, Song YB, Kim YS, Park JD. Enhancement of antitumor effects of paclitaxel (taxol) in combination with red ginseng acidic polysaccharide (RGAP). Planta Med. 2004 ; 70(11) : 1033-8. https://doi.org/10.1055/s-2004-832643
  17. Kim CM, Han GS. Radioprotective effects of ginseng proteins. Yakhak Hoeji. 1985 ; 29(5) : 246-52.
  18. Cho JH, Kim KW, Park HS, Yoon YJ, Song MY. Anti-obesity effect of Panax ginseng in animal models: Study protocol for a systematic review and meta-analysis. J Korean Med Obes Res. 2017 ; 17(1) : 37-45. https://doi.org/10.15429/jkomor.2017.17.1.37
  19. Bae MJ, Sung TS, Choi C. Effect of ginseng fraction components on plasma, adipose and feces 1 steroids in obese rat induced by a high fat diet. Korean J Ginseng Sci. 1990 ; 14(3) : 404-15.
  20. Kim SO. Ginseng saponin-Re and Coix lachrymajobi var. mayuen regulate obesity related genes expressions, TNF-alpha, leptin, lipoprotein lipase and resistin in 3T3-L1 adipocytes. Journal of Life Science. 2007 ; 17(11) : 1523-32. https://doi.org/10.5352/JLS.2007.17.11.1523
  21. Jang JG, Lee KS, Kwon DW, Nam KY, Choi JH. Study on the changes of saponin contents in relation to root age of Panax ginseng. Korean J Food Nutr. 1983 ; 12(1) : 37-40.
  22. Namba T, Yoshizaki M, Tomimori T, Kobashi K, Mitsui K. Chemical and biochemical evaluation of ginseng and related crude drugs. Yakugaku Zasshi 1974 ; 94(2) : 252-60. https://doi.org/10.1248/yakushi1947.94.2_252
  23. Ko SR, Choi KJ, Kim SC, Han KW. Content and composition of saponin compounds of Panax species. Korean J Ginseng Sci. 1995 ; 19(3) : 254-9.
  24. Kim MW, Ko SR, Choi KJ, Kim SC. Distribution of saponin in various sections of Panax ginseng root and changes of its contents according to root age. Korean J Ginseng Sci. 1987 ; 11(1) : 10-6.
  25. Lee CR, Whang WK, Shin CG, Lee HS, Han ST, Im BO, et al. Comparison of ginsenoside composition and contents in fresh ginseng roots cultivated in Korea, Japan, and China at various ages. Korean J Food Sci Technol. 2004 ; 36(5) : 847-50.
  26. Han BH, Park MH, Han YN, Suh DY. Chemical and biochemical studies on non-saponin constituents of Korean Ginseng. Korean J Ginseng Sci. 1992 ; 16(3) : 228-34.
  27. Yang BW, Im BO, Ko SK. Comparison of non-saponin composition and contents in fresh ginseng roots cultivated in different areas and at various ages. Yakhak Hoeji. 2006 ; 50(4): 205-19.
  28. Kang SH, An BK, Hwang YJ, Yang BW, Ko SK. Comparison of ginsenosides and acidic polysaccharide contents in fresh ginseng cultivated in different seasons and various ages. Kor J Pharmacogn. 2019 ; 50(4) : 305-11.
  29. Do JH, Lee HO, Lee SK, Jang JK, Lee SD, Sung HS. Colorimetric determination of acidic polysaccharide from panax gineng, its extraction condition and stability. Korean J Ginseng Sci. 1993 ; 17(2) : 139-44.
  30. Attele AS, Zhou YP, Xie JT, Wu JA. Antidiabetic effects of Panax ginseng berry extract and the identification of an effectve component. Diabetes. 2002 ; 51 : 1851-8. https://doi.org/10.2337/diabetes.51.6.1851
  31. Kim SI, Kim YS, Jeon BS, Lim CH. Effect of ginseng on fat accumulation in the obese rats induced by high fat diet. Korean J Ginseng Sci. 1986 ; 10(2) : 167-79.
  32. Lee SW, Kang SW, Kim DY, Seong NS, Park HW. Comparison of growth characteristics and compounds of ginseng cultivated by paddy and upland cultivation. Korean J Medicinal Crop Sci. 2004 ; 12(1) : 10-6.
  33. Mog SK, Son SY, Park H. Root and top growth of Panax ginseng at various soil moisture regime. Korean J Crop Sci. 1981 ; 26(1) : 115-20.
  34. Park H, Mok SK, Kim KS. Relationship between soil moisture, organic matter and plant growth in ginseng plantations. Korean Soc Soil Sci. 1982 ; 15(3) : 156-61.