Journal of Korean Neurosurgical Society

The Korean Neurosurgical Society (대한신경외과학회)
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Arachnoid Remodeling by Clipping Technique Facilitates Surgical Maneuverability during Transsphenoidal Surgery for Pituitary Macroadenoma

  • Kim, Eui Hyun (Department of Neurosurgery, Yonsei University College of Medicine) ;
  • Park, Soo Jeong (Department of Neurosurgery, Ewha Woman's University College of Medicine) ;
  • Na, Minkyun (Department of Neurosurgery, Yonsei University College of Medicine) ;
  • Moon, Ju Hyung (Department of Neurosurgery, Yonsei University College of Medicine) ;
  • Kim, Sun Ho (Department of Neurosurgery, Yonsei University College of Medicine)
  • Received : 2021.07.05
  • Accepted : 2021.12.08
  • Published : 2022.07.01
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Abstract

Objective : Pituitary adenomas frequently extend into the suprasellar space. After a suprasellar tumor is removed, the superiorly extended arachnoid becomes redundant and sinks down into the intrasellar space which often hiders visualization and accessibility to the hidden space behind the evaginated arachnoid. We introduced arachnoid remodeling by clipping technique, and evaluated its usefulness and safety during TSS. Methods : Total 223 patients who underwent arachnoid remodeling with our new clipping technique were included. Redundant arachnoid was clipped along the dural edge with multiple 2.6-mm titanium clips until the redundant arachnoid membrane no longer blocked the surgical route. To check for possible deterioration of hormonal function by this technique, we assessed anterior pituitary function of 166 patients who underwent arachnoid remodeling by clipping and compared this with those of other 429 control patients. Results : Our technique greatly enhanced the accessibility and visualization of intrasellar and parasellar spaces, both of which are generally hindered by redundant arachnoid during transsphenoidal surgery (TSS). We found no difference in anterior pituitary function between a clip-assisted arachnoid remodeling group and the control group, implying that this technique does not result in hypopituitarism. Conclusion : During TSS for pituitary adenomas with suprasellar extension, arachnoid remodeling by clipping technique is very useful and convenient for the management of the redundant arachnoid membrane to enhance visualization and surgical accessibility.

Keywords

Acknowledgement

This work was presented at the conference of the international society of pituitary surgeons (ISPS), San Diego, CA, USA (February 18-20, 2018). This study was supported by a faculty research grant of Yonsei University College of Medicine (6-2020-0224). The authors thank MID (Medical Illustration & Design), part of the Medical Research Support Services of Yonsei University College of Medicine, for all artistic support related to this work.

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