과제정보
This work was supported by the National Research Foundation of Korea (NRF) grant funded by the Korean government (MSIT) (No. 2020R1A2C2005836), and the Ministry of Education (No. 2021R1I1A1A01043143).
참고문헌
- Avena-Woods C. Overview of atopic dermatitis. Am J Manag Care. 2017 ; 23(8 Suppl) : S115-S123.
- Kim M, Kim J. Phenotypes and endotypes of atopic dermatitis: Clinical implications. Allergy Asthma Respir Dis. 2020 ; 8(1) : 9-14. https://doi.org/10.4168/aard.2020.8.1.9
- Kim JY, Yang Y. Effects of Atopic Dermatitis on Suicidal Ideation, Plans and Attempts in Young Adult. J Korean Acad Community Health Nurs. 2017 ; 28(4) : 504-12. https://doi.org/10.12799/jkachn.2017.28.4.504
- Zaidi Z, Lanigan SW. Skin: Structure and Function, Dermatology in Clinical Practice Springer. 2010: 1-15. https://doi.org/10.1007/978-1-84882-862-9_1
- Homey B, Steinhoff M, Ruzicka T, Leung DYM. Cytokines and chemokines orchestrate atopic skin inflammation. J Allergy Clin Immunol. 2006 ; 118(1) : 178-89. https://doi.org/10.1016/j.jaci.2006.03.047
- Saeki H, Tamaki K. Thymus and activation regulated chemokine (TARC)/CCL17 and skin diseases. J Dermatol Sci. 2006 ; 43(2) : 75-84. https://doi.org/10.1016/j.jdermsci.2006.06.002
- Avgerinou G, Goules AV, Stavropoulos PG, Katsambas AD. Atopic dermatitis: new immunologic aspects. Int J Dermatol. 2008 ; 47(3) : 219-24. https://doi.org/10.1111/j.1365-4632.2008.03471.x
- Jung MR, Lee TH, Bang MH, Kim H, Son Y, Chung DK, et al. Suppression of thymus- and activation-regulated chemokine (TARC/CCL17) production by 3-O-β-D-glucopyanosylspinasterol via blocking NF-κB and STAT1 signaling pathways in TNF-α and IFN-γ-induced HaCaT keratinocytes. Biochem Biophys Res Commun. 2012 ; 427(2) : 236-41. https://doi.org/10.1016/j.bbrc.2012.08.087
- Son KH, Lee JG, Jee SY. A philological study on demonstration of Atopic dermatitis. J East-West Med. 2009 ; 34(4) : 15-24.
- Gong NM, Jee SY. A Literature study about comparison of Eastern-Weatern medicine on the Atopic dermatitis. J Korean Med Ophtahlmol Otolaryngol Dermatol. 1999 ; 12 (1) : 241-53.
- Yun YH, Choi IH. A study on the Development of Traditional Korean Medicine Clinical Practice Guideline for Atopic Dermatitis. J Korean Med Ophthalmol Otolaryngol Dermatol. 2012 ; 25(2) : 38-48. https://doi.org/10.6114/JKOOD.2012.25.2.038
- Lee SY, Yoon HD, Shin OC, Park CS. A Case Report of Skin Scale Treated with Hyulbuchukeotang. Korean J Oriental Int Med. 2005;26(3):720-4
- Herbology Editorial Committee of Korean Medicine : Herbology. 2nd ed. Seoul : Younglimsa. 2009 ; 637-8.
- Kim SJ, Lee AR, Kim SH, Kim KJ, Kwon OJ, Choi JY, et al. Skin Wrinkle Improvement Effect of Paeoniae radix and processed Paeoniae radix Through inhibition of Advanced glycation end products (AGEs). Kor J Herbology. 2017 ; 32(4) : 53-60. https://doi.org/10.6116/KJH.2017.32.4.53
- Kim KH, Choi YG, Hong YM, Yeo SJ, Choi JH, Kim TH. Gene expression microarray analysis of Paeoniae radix on IL-1β-stimulated primary human gingival fibroblast. J Korean Med. 2010 ; 31(2) : 91-108
- He DY, Dai SM. Anti-inflammatory and immunomodulatory effects of paeonia lactiflora pall., a traditional chinese herbal medicine. Front Pharmacol. 2011 ; 2 : 10. https://doi.org/10.3389/fphar.2011.00010
- Hu B, Xu G, Zhang X, Xu L, Zhou H, Ma Z, et al. Paeoniflorin Attenuates Inflammatory Pain by Inhibiting Microglial Activation and Akt-NF-κB Signaling in the Central Nervous System. Cell Physiol Biochem. 2018 ; 47(2) : 842-50. https://doi.org/10.1159/000490076
- Jin X, Wang J, Xia ZM, Shang CH, Chao QL, Liu YR, et al. Anti-inflammatory and Anti-oxidative Activities of Paeonol and Its Metabolites Through Blocking MAPK/ERK/p38 Signaling Pathway. Inflammation. 2016 ; 39(1) : 434-46. https://doi.org/10.1007/s10753-015-0265-3
- Berke R, Singh A, Guralnick M. Atopic dermatitis: an overview. Am Fam Physician. 2012 ; 86(1) : 35-42
- Eckert RL. Structure, function, and differentiation of the keratinocyte. Physiol Rev. 1989 ; 69(4) : 1316-46. https://doi.org/10.1152/physrev.1989.69.4.1316
- Cha KJ, Im MA, Gu A, Kim DH, Lee D, Lee JS, et al. Inhibitory effect of Patrinia scabiosifolia Link on the development of atopic dermatitis-like lesions in human keratinocytes and NC/Nga mice. J Ethnopharmacol. 2017 ; 206 : 135-43. https://doi.org/10.1016/j.jep.2017.03.045
- Colombo I, Sangiovanni E, Maggio R, Mattozzi C, Zava S, Corbett Y, et al. HaCaT Cells as a Reliable In Vitro Differentiation Model to Dissect the Inflammatory/Repair Response of Human Keratinocytes. Mediators Inflamm. 2017 ; 2017 : 7435621. https://doi.org/10.1155/2017/7435621
- Lim JY, Lee JH, Lee DH, Lee JH, Kim DK. Umbelliferone reduces the expression of inflammatory chemokines in HaCaT cells and DNCB/DFE-induced atopic dermatitis symptoms in mice. Int Immunopharmacol. 2019 ; 75 : 105830. https://doi.org/10.1016/j.intimp.2019.105830
- Becher B, Tugues S, Greter M. GM-CSF: From Growth Factor to Central Mediator of Tissue Inflammation. Immunity. 2016 ; 45(5) : 963-73. https://doi.org/10.1016/j.immuni.2016.10.026
- Shi Y, Liu CH, Roberts AI, Das J, Xu G, Ren G, et al. Granulocyte-macrophage colony-stimulating factor (GM-CSF) and T-cell responses: what we do and don't know. Cell Res. 2006 ; 16(2) : 126-33. https://doi.org/10.1038/sj.cr.7310017
- Kaburagi Y, Shimada Y, Nagaoka T, Hasegawa M, Takehara K, Sato S. Enhanced production of CC-chemokines (RANTES, MCP-1, MIP-1α, MIP-1β, and eotaxin) in patients with atopic dermatitis. Arch Dermatol Res. 2001 ; 293(7) : 350-5. https://doi.org/10.1007/s004030100230
- Thompson WL, Van Eldik LJ. Inflammatory cytokines stimulate the chemokines CCL2/MCP-1 and CCL7/MCP-7 through NFkB and MAPK dependent pathways in rat astrocytes. Brain Res. 2009 ; 1287 : 47-57. https://doi.org/10.1016/j.brainres.2009.06.081
- di Giovine FS, Duff GW. Interleukin 1: the first interleukin. Immunol Today. 1990 ; 11(1) : 13-20. https://doi.org/10.1016/0167-5699(90)90005-t
- Lopez-Castejon G, Brough D. Understanding the mechanism of IL-1β secretion. Cytokine Growth Factor Rev. 2011 ; 22(4) : 189-95. https://doi.org/10.1016/j.cytogfr.2011.10.001
- Popa C, Netea MG, van Riel PLCM, van der Meer JWM, Stalenhoef AFH. The role of TNF-α in chronic inflammatory conditions, intermediary metabolism, and cardiovascular risk. J Lipid Res. 2007 ; 48(4) : 751-62. https://doi.org/10.1194/jlr.R600021-JLR200
- Shimada Y, Takehara K, Sato S. Both Th2 and Th1 chemokines (TARC/CCL17, MDC/CCL22, and Mig/CXCL9) are elevated in sera from patients with atopic dermatitis. J Dermatol Sci. 2004 ; 34(3) : 201-8. https://doi.org/10.1016/j.jdermsci.2004.01.001
- Neurath MF, Finotto S. IL-6 signaling in autoimmunity, chronic inflammation and inflammation-associated cancer. Cytokine Growth Factor Rev. 2011 ; 22(2) : 83-9. https://doi.org/10.1016/j.cytogfr.2011.02.003
- Amarbayasgalan T, Takahashi H, Dekio I, Morita E. Interleukin-8 content in the stratum corneum as an indicator of the severity of inflammation in the lesions of atopic dermatitis. Int Arch Allergy Immunol. 2013 ; 160(1) : 63-74. https://doi.org/10.1159/000339666
- Johnson GL, Lapadat R. Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases. Science. 2002 ; 298(5600) : 1911-2. https://doi.org/10.1126/science.1072682
- Lu N, Malemud CJ. Extracellular Signal-Regulated Kinase: A Regulator of Cell Growth, Inflammation, Chondrocyte and Bone Cell Receptor-Mediated Gene Expression. Int J Mol Sci. 2019 ; 20(15) : 3792. https://doi.org/10.3390/ijms20153792
- Masuda K, Shima H, Katagiri C, Kikuchi K. Activation of ERK induces phosphorylation of MAPK phosphatase-7, a JNK specific phosphatase, at Ser-446. J Biol Chem. 2003 ; 278(34) : 32448-56. https://doi.org/10.1074/jbc.M213254200
- Venuprasad K, Elly C, Gao M, Salek-Ardakani S, Harada Y, Luo JL, Yang C, Croft M, Inoue K, Karin M, Liu YC. Convergence of Itch-induced ubiquitination with MEKK1-JNK signaling in Th2 tolerance and airway inflammation. J Clin Invest. 2006 ; 116 : 1117-26. https://doi.org/10.1172/JCI26858
- Lawrence T. The nuclear factor NF-κβ pathway in inflammation. Cold Spring Harb Perspect Biol. 2009 ;1(6) : a001651. https://doi.org/10.1101/cshperspect.a001651
- Celec P. Nuclear factor kappa B--molecular biomedicine: the next generation. Biomed Pharmacother. 2004 ; 58(6-7) : 365-71. https://doi.org/10.1016/j.biopha.2003.12.015
- Durand JK, Baldwin AS. Targeting IKK and NF-κB for Therapy. Adv Protein Chem Struct Biol. 2017 ; 107 : 77-115. https://doi.org/10.1016/bs.apcsb.2016.11.006