Acknowledgement
This work was supported by clinical research grant from Pusan National University Hospital 2021. This research was supported by a grant of the Korea Health Technology R&D Project through the Korea Health Industry Development Institute (KHIDI), funded by the Ministry of Health & Welfare, Republic of Korea (grant number : HF21C0156).
References
- Kim IR, Kim HC, Kook YB, Park SJ, Park YG, Park GH, et al. Textbook Compilation Committee of National University of Korean Medicine. Herbology. Seoul: Younglimsa. 2009:311.
- Kim, H. J., Mawla, I., Lee, J. C., Gerber, J., Walker, K., Kim, J. E., et al. (2020). Reduced tactile acuity in chronic low back pain is linked with structural neuroplasticity in primary somatosensory cortex and is modulated by acupuncture therapy. Neuroimage, 217, 116899. https://doi.org/10.1016/j.neuroimage
- Kim, J. P. & Jung, H. J. (2021). Trends in the development of new drugs using natural products. BRIC View, 2021-T01. Available from:URL: https://www.ibric.org/myboard/read.php?Board=report&id=3684
- Go, K. H. Analysis of trends in patent applications in the healthcare field. In:Kim JY, editor. KHIDI Brief. 78th ed. Seoul:Korean Health Industry Development Institute. 2013:1-8.
- Narin, F., Noma, E., & Perry, R. (1987). Patents as indicators of corporate technological strength. Research Policy, 16(2-4), 143-55. https://doi.org/10.1016/0048-7333(87)90028-X
- Narin, F. (1994). Patent bibliometrics. Sceintometrics, 30(1), 147-55. https://doi.org/10.1007/BF02017219
- Huang, M. H., Chiang, L. Y., & Chen, D.Z. (2003). Constructing a patent citation map using bibliographic coupling: A study of Taiwan's high tech companies. Scientometrics, 58(3), 489-506. https://doi.org/10.1023/B:SCIE.0000006876.29052.bf
- Jung, E. K. (2021). 2021 Current status and issues of chronic disease. Seoul, Korea : Korea Disease Control and Prevention Agency. Retrieved from https://www.kdca.go.kr/
- Centers for Disease Control and Prevention. Drug Overdose [Internet] 2021 [cited 2022 Jan 17]. Available from:URL: https://www.cdc.gov/drugoverdose/epidemic/index.html
- An, G.S. (2016). Trends in the development of new natural drugs and Strategies for the development of new global drugs. Korean Society for Molecular and Cellular Biology, 1-7. Retrieved from https://www.ksmcb.or.kr/
- Mi, L., Li, Y. C., Sun, M. R., Zhang, P. L., Li, Y., & Yang, H. (2021). A systematic review of pharmacological activities, toxicological mechanisms and pharmacokinetic studies on aconitum alkloids. Chinese Journal of Natural Medicines, 19(7), 505-20. https://doi.org/10.1016/S1875-5364(21)60050-X
- Chan, T. Y. K. (2009). Aconite poisoning. Clin Toxicol(Phila), 47(4), 279-85. https://doi.org/10.1080/15563650902904407
- Ou, B. U. (2015). A method of reducing of toxic substance in Korean aconite root. Korea Patent 1014952050000. https://doi.org/10.8080/1020130032636
- Korea Research Institute of Bioscience and Biotechnology. (2011). Pharmaceutical and health food composition for preventing or treating diabetic foot ulcer comprising decotion or extracts of aconitum jaluense as effective component. Korea Patent 1010406280000. https://doi.org/10.8080/1020090110112
- Ou, B. U. (2013). A method for preparing a pill or granule type fermented composition comprising the extract of complex herb useful in treating rheumatic disease. Korea patent 1012512070000. https://doi.org/10.8080/1020110021882