DOI QR코드

DOI QR Code

Extramedullary Relapse of Acute Lymphoblastic Leukemia Involving the Parotid Gland: A Case Report and Literature Review

급성 림프아구성 백혈병 환자의 이하선에 발생한 골수외 재발: 증례 보고와 문헌 고찰

  • Nim Lee (Departments of Radiology, Medical Research Institute, College of Medicine, Ewha Womans University Mokdong Hospital) ;
  • Hyun-Hae Cho (Departments of Radiology, Medical Research Institute, College of Medicine, Ewha Womans University Mokdong Hospital) ;
  • Min-Sun, Cho (Departments of Pathology, Medical Research Institute, College of Medicine, Ewha Womans University Seoul Hospital)
  • 이님 (이화여자대학교 의과대학 이화여자대학교 목동병원 영상의학과) ;
  • 조현혜 (이화여자대학교 의과대학 이화여자대학교 목동병원 영상의학과) ;
  • 조민선 (이화여자대학교 의과대학 이화여자대학교 서울병원 병리학과)
  • Received : 2021.03.27
  • Accepted : 2021.06.29
  • Published : 2022.03.01

Abstract

While extramedullary relapse of leukemia could occur, the parotid gland is a rare site of recurrence. Extramedullary relapse involving the parotid gland could be mistaken for other diseases. Moreover, the diagnosis of this disease is often delayed due to its rarity. Herein, we present a case of extramedullary relapse of acute lymphoblastic leukemia involving the parotid gland.

백혈병의 골수 외 재발이 발생할 수 있지만 이하선은 드문 재발 부위이다. 이하선을 포함하는 골수 외 재발은 다른 질환과 혼동될 수 있으며 종종 질환의 희귀성으로 인해 진단이 지연될 수 있다. 이에 저자들은 재발성 급성 림프아구성 백혈병 환자에서 이하선의 급성 림프아구성 백혈병의 골수 외 재발 사례와 영상 소견을 보고한다.

Keywords

References

  1. Mjali A, Al-Shammari HHJ, Hasan DM, Alqanbar MF, Al-Anssari MJ. Bilateral parotid glands swelling and facial palsy as relapsing symptom in adult patient with acute lymphoblastic leukemia: a case report. World J Pharm Res 2018;7:37-42 
  2. Kim JY, Im SA, Lee JH, Lee JW, Chung NG, Cho B. Extramedullary relapse of acute myeloid and lymphoid leukemia in children: a retrospective analysis. Iran J Pediatr 2016;26:e1711 
  3. Clark WB, Strickland SA, Barrett AJ, Savani BN. Extramedullary relapses after allogeneic stem cell transplantation for acute myeloid leukemia and myelodysplastic syndrome. Haematologica 2010;95:860-863 
  4. Lahuri YS, Mohamad I, Ismail MIM, Hashim H, Ibrahim H. Unilateral parotid gland swelling as the sole presenting symptom of acute lymphoblastic leukaemia in children. Egypt J Ear Nose Throat Allied Sci 2015;6:279-282 
  5. Brooks KG, Thompson DF. A review and assessment of drug-induced parotitis. Ann Pharmacother 2012;46:1688-1699 
  6. unal S,, Ku,skonmaz B, BalcI YI, Cengiz B, Tuncer M, Gurgey A, et al. An unusual presentation of pediatric acute lymphoblastic leukemia with parotid gland involvement and dactylitis. Turk J Haematol 2010;27:117-119 
  7. Freyer DR, Devidas M, La M, Carroll WL, Gaynon PS, Hunger SP, et al. Postrelapse survival in childhood acute lymphoblastic leukemia is independent of initial treatment intensity: a report from the Children's Oncology Group. Blood 2011;117:3010-3015 
  8. Park J, Park SY, Cho HI, Lee D. Isolated extramedullary relapse in the pleural fluid of a patient with acute myeloid leukemia following allogeneic BMT. Bone Marrow Transplant 2002;30:57-59 
  9. Dinsmore R, Kirkpatrick D, Flomenberg N, Gulati S, Kapoor N, Shank B, et al. Allogeneic bone marrow transplantation for patients with acute lymphoblastic leukemia. Blood 1983;62:381-388