Applied Chemistry for Engineering (공업화학)

The Korean Society of Industrial and Engineering Chemistry (한국공업화학회)
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The Role of Acid in the Synthesis of Red-Emitting Carbon Dots

장파장 형광 탄소 양자점 제조에 있어서 산의 역할에 대한 연구

  • Yun, Sohee (Department of Chemical and Biological Engineering, Hanbat National University) ;
  • Lee, Jinhee (Department of Chemical and Biological Engineering, Hanbat National University) ;
  • Choi, Jin-sil (Department of Chemical and Biological Engineering, Hanbat National University)
  • 윤소희 (한밭대학교 화학생명공학과) ;
  • 이진희 (한밭대학교 화학생명공학과) ;
  • 최진실 (한밭대학교 화학생명공학과)
  • Received : 2022.05.02
  • Accepted : 2022.05.27
  • Published : 2022.06.10
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Abstract

Carbon dots (CDs) are few nanometer-sized carbon-based nanoparticles and emerging candidate materials in various fields such as biosensors and bioimaging due to their excellent optical properties and high biocompatibility. However, most CDs, emitting blue light, have limited their application in biomedical fields due to the low penetration of short-wavelength lights into the biological system. Therefore, there has been enormous need to develop long-wavelength emitting CDs. In this study, red-emitting CDs were successfully synthesized through the hydrothermal reaction of p-phenylenediamine with hydrochloric acid. In addition, the effect of the amount of hydrochloric acid on the formation of carbon dots, resulting in the variation of the chemical structures of CDs, were investigated, which was confirmed with the intensive structural analyses using infrared and X-ray photoelectron spectroscopy. It was found that the chemical structure of CDs governed their optical properties and quantum yield. Therefore, this study provides an insight into the role of acid in forming red-emitting CDs as the optimal probe for biomedical application.

탄소점은 수 nm 크기의 탄소 기반 나노 입자로서 높은 생체 적합성, 우수한 발광 특성 등의 장점으로 인해 바이오 센서 및 바이오 이미징 등 다양한 분야에 응용되고 있다. 하지만 청색광을 발광하는 대부분의 탄소점은 해당 파장의 빛이 생물학적 조직에 대해서 약한 침투성을 보여주기 때문에 생물 의학 분야에서 응용에 한계가 있다. 이를 극복하기 위해 장파장 영역에서의 형광을 방출하는 탄소점 개발의 필요성이 커지고 있다. 본 연구에서는 p-페닐렌다이아민에 염산을 첨가하여 산화 후 중합시킴으로써 장파장 빛을 발광하는 탄소점을 획득할 수 있었다. 이때 염산의 양에 따라 탄소점의 화학적 구조가 영향을 받음을 적외선 분광과 X-선 광전자 분광 분석을 통해 확인할 수 있었다. 이러한 탄소점의 화학적 구조 변화는 이들의 흡광, 형광, 그리고 형광 수율에 영향을 끼쳤다. 이 연구는 장파장을 가지는 탄소점을 합성함에 있어서 영향을 주는 인자 (산)에 대한 이해를 높일 수 있었으며 이를 기반으로 바이오 센서 등의 다양한 생물의학 분야에 높은 응용 가능성을 가지는 효과적인 탄소점의 설계가 가능할 것으로 보인다.

Keywords

Acknowledgement

본 연구는 정부(과학기술정보통신부)의 재원으로 한국 연구 재단의 지원을 받아 수행된 연구임(No. 2020R1C1C101186312314820922601).

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