대한한의학방제학회지 (Herbal Formula Science)

  • 제30권2호
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  • Pages.95-100
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  • 2022
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  • 1229-1218(pISSN)
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  • 2288-5641(eISSN)
대한한의학방제학회 (The Korean Medicine Society for the Herbal Formula Study)
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DOI QR코드

DOI QR Code

류마티스 관절염 치료제와 병용한 독활기생탕의 효과 및 안전성: 체계적 문헌고찰 및 메타분석 프로토콜

The Effectiveness and Safety of Dokwhalkisaeng-tang Combined with the Medication on Rheumatoid Arthritis: A Study Protocol for Systematic Review and Meta-analysis

  • 채수연 (동국대학교 분당한방병원 사상체질과) ;
  • 정찬영 (동국대학교 일산한방병원 침구의학과) ;
  • 김주희 (상지대학교 한의과대학) ;
  • 김은정 (동국대학교 분당한방병원 침구의학과) ;
  • 서병관 (경희대학교 한의과대학) ;
  • 황민섭 (동국대학교 한의과대학) ;
  • 박성식 (동국대학교 분당한방병원 사상체질과) ;
  • 김경호 (동국대학교 일산한방병원 침구의학과) ;
  • 윤종화 (동국대학교 한의과대학) ;
  • 성원석 (동국대학교 분당한방병원 침구의학과)
  • Chae, Soo-Yeon (Department of Sasang Constitutional Medicine, Dongguk University Bundang Oriental Hospital) ;
  • Jung, Chan-Yung (Department of Acupuncture & Moxibustion, Dongguk University Ilsan Oriental Hospital) ;
  • Kim, Joo-Hee (College of Korean Medicine, Sangji University) ;
  • Kim, Eun-Jung (Department of Acupuncture & Moxibustion, Dongguk University Bundang Oriental Hospital) ;
  • Seo, Byung-Kwan (College of Korean Medicine, Kyung Hee University) ;
  • Hwang, Min-Seop (College of Korean Medicine, Dongguk University) ;
  • Park, Seong-Sik (Department of Sasang Constitutional Medicine, Dongguk University Bundang Oriental Hospital) ;
  • Kim, Kyung-Ho (Department of Acupuncture & Moxibustion, Dongguk University Ilsan Oriental Hospital) ;
  • Yoon, Jong-hwa (College of Korean Medicine, Dongguk University) ;
  • Sung, Won-Suk (Department of Acupuncture & Moxibustion, Dongguk University Bundang Oriental Hospital)
  • 투고 : 2022.05.11
  • 심사 : 2022.05.16
  • 발행 : 2022.05.31
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초록

Objectives : Recent studies reported that Dokwhalkisaeng-tang (DHJST) could relieve the clinical rheumatoid arthritis (RA) symptoms and the level of RA-related blood test. However, evidence-based review on effectiveness and safety of DHJST with medication on RA was not yet provided. Methods : Searching randomized controlled trials on the use of DHJST for RA will be performed using multiple electronic databases, manual search, and contact to author. Studies will be selected according to the pre-defined criteria and collected data on study participants, interventions, control groups, outcome measurements, the results, adverse events, and risk of bias will be summarized. Primary outcome will be the disease activity score (including effective rate, swollen joint count, tender joint count, and morning stiffness), and the secondary outcomes will be RA-related blood test and adverse events. We will use Review Manager software to perform a meta-analysis, Cochrane Collaboration "risk of bias" tool for assessing the risk of bias, and Grades of Recommendation, Assessment, Development and Evaluation for the determination of quality of evidence. Results : We are going to investigate the effectiveness and safety of DHJST with medication for RA. Conclusion : This study will provide reliable evidence on whether DHJST combined with medicine is more effective on RA than medicine monotherapy.

키워드

과제정보

This study was supported by the Traditional Korean Medicine R&D program funded by the Ministry of Health and Welfare through the Korean Health Industry Development Institute (KHIDI) (grant No. HF21C0077). Funder only provided the financial support and did not involve in this article including the review, editing, or the submission for publication.

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