과제정보
This study was supported by the grant (No. 02-2015-011) from Seoul National University Bundang Hospital (SNUBH) Research Fund and the National Research Foundation of Korea (NRF) grant funded by the Korea government (MSIT) (No. 2020R1F1A1070600). We also express our sincere gratitude to Amb. Hong-choo Hyun and his wife for their kind donation.
참고문헌
- Akira S, Uematsu S, Takeuchi O. Pathogen recognition and innate immunity. Cell 2006;124:783-801. https://doi.org/10.1016/j.cell.2006.02.015
- Lee CG, Da Silva CA, Dela Cruz CS, Ahangari F, Ma B, Kang MJ, He CH, Takyar S, Elias JA. Role of chitin and chitinase/chitinase-like proteins in inflammation, tissue remodeling, and injury. Annu Rev Physiol 2011;73:479-501. https://doi.org/10.1146/annurev-physiol-012110-142250
- Martorano LM, Grayson MH. Respiratory viral infections and atopic development: from possible mechanisms to advances in treatment. Eur J Immunol 2018;48:407-414. https://doi.org/10.1002/eji.201747052
- Sigurs N, Gustafsson PM, Bjarnason R, Lundberg F, Schmidt S, Sigurbergsson F, Kjellman B. Severe respiratory syncytial virus bronchiolitis in infancy and asthma and allergy at age 13. Am J Respir Crit Care Med 2005;171:137-141. https://doi.org/10.1164/rccm.200406-730OC
- Bacharier LB, Cohen R, Schweiger T, Yin-Declue H, Christie C, Zheng J, Schechtman KB, Strunk RC, Castro M. Determinants of asthma after severe respiratory syncytial virus bronchiolitis. J Allergy Clin Immunol 2012;130:91-100.e3. https://doi.org/10.1016/j.jaci.2012.02.010
- Kawai T, Akira S. The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors. Nat Immunol 2010;11:373-384. https://doi.org/10.1038/ni.1863
- Saglani S. Viral infections and the development of asthma in children. Ther Adv Infect Dis 2013;1:139-150. https://doi.org/10.1177/2049936113497202
- Lee JJ, Kim SH, Lee MJ, Kim BK, Song WJ, Park HW, Cho SH, Hong SJ, Chang YS, Kim BS. Different upper airway microbiome and their functional genes associated with asthma in young adults and elderly individuals. Allergy 2019;74:709-719. https://doi.org/10.1111/all.13608
- Song WJ, Sintobin I, Sohn KH, Kang MG, Park HK, Jo EJ, Lee SE, Yang MS, Kim SH, Park HK, et al. Staphylococcal enterotoxin IgE sensitization in late-onset severe eosinophilic asthma in the elderly. Clin Exp Allergy 2016;46:411-421. https://doi.org/10.1111/cea.12652
- Kim YC, Won HK, Lee JW, Sohn KH, Kim MH, Kim TB, Chang YS, Lee BJ, Cho SH, Bachert C, et al. Staphylococcus aureus nasal colonization and asthma in adults: systematic review and meta-analysis. J Allergy Clin Immunol Pract 2019;7:606-615.e9. https://doi.org/10.1016/j.jaip.2018.08.020
- Song WJ, Chang YS, Lim MK, Yun EH, Kim SH, Kang HR, Park HW, Tomassen P, Choi MH, Min KU, et al. Staphylococcal enterotoxin sensitization in a community-based population: a potential role in adult-onset asthma. Clin Exp Allergy 2014;44:553-562. https://doi.org/10.1111/cea.12239
- Morgene MF, Botelho-Nevers E, Grattard F, Pillet S, Berthelot P, Pozzetto B, Verhoeven PO. Staphylococcus aureus colonization and non-influenza respiratory viruses: Interactions and synergism mechanisms. Virulence 2018;9:1354-1363. https://doi.org/10.1080/21505594.2018.1504561
- Choi JP, Kim YS, Kim OY, Kim YM, Jeon SG, Roh TY, Park JS, Gho YS, Kim YK. TNF-alpha is a key mediator in the development of Th2 cell response to inhaled allergens induced by a viral PAMP double-stranded RNA. Allergy 2012;67:1138-1148. https://doi.org/10.1111/j.1398-9995.2012.02871.x
- Choi JP, Kim YM, Choi HI, Choi SJ, Park HT, Lee WH, Gho YS, Jee YK, Jeon SG, Kim YK. An important role of tumor necrosis factor receptor-2 on natural killer T cells on the development of dsRNA-enhanced Th2 cell response to inhaled allergens. Allergy 2014;69:186-198. https://doi.org/10.1111/all.12301
- Byrne AJ, Mathie SA, Gregory LG, Lloyd CM. Pulmonary macrophages: key players in the innate defence of the airways. Thorax 2015;70:1189-1196. https://doi.org/10.1136/thoraxjnl-2015-207020
- Rieckmann P, Michel U, Albrecht M, Bruck W, Wockel L, Felgenhauer K. Soluble forms of intercellular adhesion molecule-1 (ICAM-1) block lymphocyte attachment to cerebral endothelial cells. J Neuroimmunol 1995;60:9-15. https://doi.org/10.1016/0165-5728(95)00047-6
- Mendez MP, Monroy YK, Du M, Preston AM, Tolle L, Lin Y, VanDussen KL, Samuelson LC, Standiford TJ, Curtis JL, et al. Overexpression of sICAM-1 in the alveolar epithelial space results in an exaggerated inflammatory response and early death in Gram negative pneumonia. Respir Res 2011;12:12.
- Bachelerie F, Ben-Baruch A, Burkhardt AM, Combadiere C, Farber JM, Graham GJ, Horuk R, Sparre-Ulrich AH, Locati M, Luster AD, et al. International Union of Basic and Clinical Pharmacology. [corrected]. LXXXIX. Update on the extended family of chemokine receptors and introducing a new nomenclature for atypical chemokine receptors. Pharmacol Rev 2013;66:1-79. https://doi.org/10.1124/pr.113.007724
- Yuan XH, Li YM, Shen YY, Yang J, Jin Y. Clinical and Th1/Th2 immune response features of hospitalized children with human rhinovirus infection. J Med Virol 2020;92:26-33. https://doi.org/10.1002/jmv.25587
- Vojvoda V, Savic Mlakar A, Jergovic M, Kukuruzovic M, Markovinovic L, Aberle N, Rabatic S, Bendelja K. The increased type-1 and type-2 chemokine levels in children with acute RSV infection alter the development of adaptive immune responses. BioMed Res Int 2014;2014:750521.
- Kanehiro A, Lahn M, Makela MJ, Dakhama A, Fujita M, Joetham A, Mason RJ, Born W, Gelfand EW. Tumor necrosis factor-alpha negatively regulates airway hyperresponsiveness through gamma-delta T cells. Am J Respir Crit Care Med 2001;164:2229-2238. https://doi.org/10.1164/ajrccm.164.12.2012059
- Rudmann DG, Moore MW, Tepper JS, Aldrich MC, Pfeiffer JW, Hogenesch H, Tumas DB. Modulation of allergic inflammation in mice deficient in TNF receptors. Am J Physiol Lung Cell Mol Physiol 2000;279:L1047-L1057. https://doi.org/10.1152/ajplung.2000.279.6.L1047
- Tsukamoto H, Senju S, Matsumura K, Swain SL, Nishimura Y. IL-6-mediated environmental conditioning of defective Th1 differentiation dampens antitumour immune responses in old age. Nat Commun 2015;6:6702.
- Diehl S, Anguita J, Hoffmeyer A, Zapton T, Ihle JN, Fikrig E, Rincon M. Inhibition of Th1 differentiation by IL-6 is mediated by SOCS1. Immunity 2000;13:805-815. https://doi.org/10.1016/S1074-7613(00)00078-9
- Velazquez-Salinas L, Verdugo-Rodriguez A, Rodriguez LL, Borca MV. The role of interleukin 6 during viral infections. Front Microbiol 2019;10:1057.
- Lee YK, Turner H, Maynard CL, Oliver JR, Chen D, Elson CO, Weaver CT. Late developmental plasticity in the T helper 17 lineage. Immunity 2009;30:92-107. https://doi.org/10.1016/j.immuni.2008.11.005
- Zhou L, Chong MM, Littman DR. Plasticity of CD4+ T cell lineage differentiation. Immunity 2009;30:646-655. https://doi.org/10.1016/j.immuni.2009.05.001
- Zhou JH, Wang YN, Chang QY, Ma P, Hu Y, Cao X. Type iii interferons in viral infection and antiviral immunity. Cell Physiol Biochem 2018;51:173-185. https://doi.org/10.1159/000495172
- Longhi MP, Trumpfheller C, Idoyaga J, Caskey M, Matos I, Kluger C, Salazar AM, Colonna M, Steinman RM. Dendritic cells require a systemic type I interferon response to mature and induce CD4+ Th1 immunity with poly IC as adjuvant. J Exp Med 2009;206:1589-1602. https://doi.org/10.1084/jem.20090247
- Nuriev R, Johansson C. Chemokine regulation of inflammation during respiratory syncytial virus infection. F1000 Res 2019;8:1837.
- Schaller M, Hogaboam CM, Lukacs N, Kunkel SL. Respiratory viral infections drive chemokine expression and exacerbate the asthmatic response. J Allergy Clin Immunol 2006;118:295-302. https://doi.org/10.1016/j.jaci.2006.05.025
- Okano M, Fujiwara T, Kariya S, Higaki T, Makihara S, Haruna T, Noyama Y, Koyama T, Omichi R, Orita Y, et al. Regulatory effect of TLR3 signaling on staphylococcal enterotoxin-induced IL-5, IL-13, IL-17A and IFN-γ production in chronic rhinosinusitis with nasal polyps. Allergol Int 2016;65:96-102. https://doi.org/10.1016/j.alit.2015.08.005
- Abdi K, Singh NJ, Matzinger P. Lipopolysaccharide-activated dendritic cells: "exhausted" or alert and waiting? J Immunol 2012;188:5981-5989. https://doi.org/10.4049/jimmunol.1102868
- Huvenne W, Callebaut I, Reekmans K, Hens G, Bobic S, Jorissen M, Bullens DM, Ceuppens JL, Bachert C, Hellings PW. Staphylococcus aureus enterotoxin B augments granulocyte migration and survival via airway epithelial cell activation. Allergy 2010;65:1013-1020. https://doi.org/10.1111/j.1398-9995.2009.02313.x
- Robinson SC, Scott KA, Balkwill FR. Chemokine stimulation of monocyte matrix metalloproteinase-9 requires endogenous TNF-alpha. Eur J Immunol 2002;32:404-412. https://doi.org/10.1002/1521-4141(200202)32:2<404::AID-IMMU404>3.0.CO;2-X
- Sekiya T, Miyamasu M, Imanishi M, Yamada H, Nakajima T, Yamaguchi M, Fujisawa T, Pawankar R, Sano Y, Ohta K, et al. Inducible expression of a Th2-type CC chemokine thymus- and activation-regulated chemokine by human bronchial epithelial cells. J Immunol 2000;165:2205-2213. https://doi.org/10.4049/jimmunol.165.4.2205
- Kurt-Jones EA, Popova L, Kwinn L, Haynes LM, Jones LP, Tripp RA, Walsh EE, Freeman MW, Golenbock DT, Anderson LJ, et al. Pattern recognition receptors TLR4 and CD14 mediate response to respiratory syncytial virus. Nat Immunol 2000;1:398-401. https://doi.org/10.1038/80833
- Martinez FD. Development of wheezing disorders and asthma in preschool children. Pediatrics 2002;109:362-367. https://doi.org/10.1542/peds.109.SE1.362
- Stein RT, Sherrill D, Morgan WJ, Holberg CJ, Halonen M, Taussig LM, Wright AL, Martinez FD. Respiratory syncytial virus in early life and risk of wheeze and allergy by age 13 years. Lancet 1999;354:541-545. https://doi.org/10.1016/S0140-6736(98)10321-5
- Lemanske RF Jr. Inflammation in childhood asthma and other wheezing disorders. Pediatrics 2002;109:368-372. https://doi.org/10.1542/peds.109.SE1.368
- Jackson DJ, Gangnon RE, Evans MD, Roberg KA, Anderson EL, Pappas TE, Printz MC, Lee WM, Shult PA, Reisdorf E, et al. Wheezing rhinovirus illnesses in early life predict asthma development in high-risk children. Am J Respir Crit Care Med 2008;178:667-672. https://doi.org/10.1164/rccm.200802-309OC
- Jackson DJ, Evans MD, Gangnon RE, Tisler CJ, Pappas TE, Lee WM, Gern JE, Lemanske RF Jr. Evidence for a causal relationship between allergic sensitization and rhinovirus wheezing in early life. Am J Respir Crit Care Med 2012;185:281-285. https://doi.org/10.1164/rccm.201104-0660OC
- Sigurs N, Aljassim F, Kjellman B, Robinson PD, Sigurbergsson F, Bjarnason R, Gustafsson PM. Asthma and allergy patterns over 18 years after severe RSV bronchiolitis in the first year of life. Thorax 2010;65:1045-1052.