Advances in materials Research

  • 제11권2호
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  • Pages.165-170
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  • 2022
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  • 2234-0912(pISSN)
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  • 2234-179X(eISSN)
테크노프레스 (Techno-Press)
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DOI QR코드

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Evaluating the absorption loading technique to acrylic resin for drug delivery

  • Al-Kaabi, Arshad F. (Department of Dental Technology, College of Health and Medical Technology, Middle Technical University) ;
  • Hamid, Mohammed A. (Department of Dental Technology, College of Health and Medical Technology, Middle Technical University)
  • 투고 : 2020.09.10
  • 심사 : 2022.01.09
  • 발행 : 2022.06.25
⟨ 이전 논문 다음 논문 ⟩

초록

Acrylic resin or polymethylmethacrylate (PMMA) is one of the most attractive materials to be used for dental appliances manufacturing. It has been introduced as a biomaterial during the last century. This study aims to evaluate the compounds absorption and release through acrylic resin to be used for drug delivery as well. The study specimens were 10 pieces of heat-cured clear acrylic resin with dimensions of 10 × 10 × 2 mm. The specimens were dipped in methylene blue solution at a powder-water ratio of 1:20 for 5 days. The samples were removed and dipped in 5 ml distilled water vials for 24 hours. Then the specimens were replaced into new 5 ml vials and the process lasted for 4 days. The extracted solutions were analyzed by the visible light spectroscopy for absorbance. The statistical results showed a gradual increase in stain release from day 1 to day 4 with a significant difference between day 1 and day 4 solutions. The study showed that PMMA resin is able to absorb and release some compounds constantly and the absorption drug-loading technique is applicable to this material.

키워드

참고문헌

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