Journal of Gastric Cancer

The Korean Gastric Cancer Association (대한위암학회)
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Larger Remaining Stomach Volume Is Associated With Better Nutrition and Muscle Preservation in Patients With Gastric Cancer Receiving Distal Gastrectomy With Gastroduodenostomy

  • Kim, Amy (Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Lee, Jung-Bok (Division of Biostatistics, Center for Medical Research and Information, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Ko, Yousun (Biomedical Research Center, Asan Institute for Life Sciences, Asan Medical Center) ;
  • Park, Taeyong (Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine) ;
  • Jo, Hyeonjong (Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine) ;
  • Jang, Jin Kyoo (Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine) ;
  • Lee, Kyoungsuk (Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Kim, Kyung Won (Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine) ;
  • Lee, In-Seob (Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine)
  • Received : 2022.03.18
  • Accepted : 2022.04.26
  • Published : 2022.04.30
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Abstract

Purpose: Weight loss and deterioration in body composition are observed in patients with gastric cancer (GC) following gastrectomy. This study aimed to investigate the impact of residual stomach volume (RSV) on the nutritional status and body composition of patients with GC treated with distal gastrectomy. Materials and Methods: In total, 227 patients who underwent minimally invasive distal gastrectomy with Billroth 1 anastomosis for stage I GC between February 2015 and May 2018 were enrolled. Clinicodemographic and laboratory data were collected from the GC registry. The RSV, abdominal muscle area, and subcutaneous/visceral fat areas were measured using computed tomography data. Results: A larger RSV was associated with a lower decrease in the nutritional risk index (P=0.004) and hemoglobin level (P=0.003) during the first 3 months after surgery, and better recovery at 12 months. A larger RSV demonstrated an advantage in the preservation of abdominal muscle area (P=0.02) and visceral fat (P=0.04) after surgery, as well as less reduction in weight (P=0.02) and body mass index (P=0.03). Conclusions: Larger RSV was associated with improved nutritional status and better preservation of muscle and fat after distal gastrectomy.

Keywords

Acknowledgement

This study was supported by a grant from Asan Institute for Life Sciences and Corporate Relations of Asan Medical Center, Seoul, Korea (2017IT0216), the Korea Health Technology R&D Project through the Korea Health Industry Development Institute (KHIDI), funded by the Ministry of Health & Welfare, Republic of Korea (No. HI18C1216), and the National Research Foundation of Korea (NRF) grand funded by the Korea government (MSIT) (No. NRF-2020R1F1A1048267). The authors declare that they have no conflicts of interest.

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