Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics (대한후두음성언어의학회지)

The Korean Society of Laryngology, Phoniatrics and Logopedics. (대한후두음성언어의학회)
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The Benefit of Supplemental Cough Suppression Therapy for Chronic Refractory Cough

만성 난치성 기침에 대한 기침 억제 요법의 효과

  • Yoo, Yong Jun (Department of Otorhinolaryngology-Head and Neck Surgery, Inha University College of Medicine) ;
  • Park, Hye Jin (Department of Otolaryngology, Ulsan University Hospital, University of Ulsan College of Medicine) ;
  • Han, Myung Woul (Department of Otolaryngology, Ulsan University Hospital, University of Ulsan College of Medicine) ;
  • Kim, Ji Won (Department of Otorhinolaryngology-Head and Neck Surgery, Inha University College of Medicine)
  • 유용준 (인하대학교 의과대학 이비인후과학교실) ;
  • 박혜진 (울산대학교 의과대학 울산대학교병원 이비인후과학교실) ;
  • 한명월 (울산대학교 의과대학 울산대학교병원 이비인후과학교실) ;
  • 김지원 (인하대학교 의과대학 이비인후과학교실)
  • Received : 2022.02.06
  • Accepted : 2022.03.26
  • Published : 2022.04.30
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Abstract

Background and Objectives Cough suppression therapy (CST) is a physiotherapy that can be used for patients with chronic refractory cough (CRC). We aimed to investigate the efficacy of CST for CRC. Materials and Method A prospective randomized controlled trial was conducted in 27 patients with CRC. Participants were randomized to receive either standard mucolytic medications for CRC combined with supplemental CST (CST group) or standard medications alone (control group). CST consists of laryngeal hygiene management, humidification, cough suppression technique, breathing method, and counseling. We assessed the symptoms change at baseline and week 4 with the Leicester Cough Questionnaire (LCQ). Secondary efficacy outcomes included the degree of cough Visual Analog Scale (VAS) score (0 to 100 scale). Results From 2019 to 2021, 14 CST group patients and 13 control group patients were included. The improvement was significantly greater in the CST group than in the control group for cough VAS score (36.67 to 13.33 vs. 74.29 to 16.43, p<0.001). Patients in the CST group had a significant improvement in total (70.14 to 107.71, p=0.005), physical (31.42 to 43.86, p=0.015), psychological (23.57 to 40.14, p=0.003), and social (15.14 to 23.71, p=0.005) LCQ scores. However, there was not a significant pre- to post-treatment LCQ score improvement in control group. Conclusion CST might be an effective supplemental intervention for CRC.

Keywords

Acknowledgement

This work was supported by Inha University Research Grant.

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