References
- Statistics Korea, (2021, December 2). Statistics Korea government official work conference: National quality of life index - Life expectancy at birth. Retrieved from https://www.index.go.kr/unify/idx-info.do?idxCd=8016
- Statistics Korea, (2021, January 8). Statistics Korea government official work conference: National development index - Health life expectancy. Retrieved from http://www.index.go.kr/ unify/idx-info.do?idxCd=5067
- Kim, M.K., Tak, Y.J., Kang, G.W., Hong, J.Y., Factors of individual and community levels affecting health-related quality of life. J. Korean Data Anal. Soc., 19, 1025-1037 (2017). https://doi.org/10.37727/jkdas.2017.19.2.1025
- Kim, Y.H., Lee, J.H., The relationship of quality of health-related life with the status of oral health in adults. J. Korean Acad. Oral Health, 40, 165-170 (2016). https://doi.org/10.11149/jkaoh.2016.40.3.165
- Health Insurance Review & Assessment Service, (2021, November 1). Healthcare Bigdata Hub - multiple-frequency diseases statistics. Retrieved from http://opendata.hira.or.kr/op/opc/olapHifrqSickInfo.do#none
- Lee, S.H., Shin, B.M., Song, G.I., Shin, S.J., Bae, S.M., Association between sugary snacking habits and oral disease in Korean adults. J. Korean Soc. Dent. Hyg., 20, 29-39 (2020).
- Moynihan, P., Sugars and dental caries: Evidence for setting a recommended threshold for intake. Adv. Nutr., 7, 149-56 (2016). https://doi.org/10.3945/an.115.009365
- Rippe, J.M., Angelopoulosm T.J., Relationship between added sugars consumption and chronic disease risk factors: current understanding. Nutrients, 8, 697 (2016). https://doi.org/10.3390/nu8110697
- Ha, A.W., Kim, W.K., The food and nutrient intakes from daily processed food in Korean adults: based on the 6th Korea National Health and Nutrition Examination Survey data (2013-2015). J. Nutr. Health, 52, 422-434 (2019). https://doi.org/10.4163/jnh.2019.52.5.422
- National Institute of Food and Drug Safety Evaluation, (2021, January 27). Press release - Need attention because children and adolescents consume a lot of sugar per day. Retrieved from http://www.nifds.go.kr/brd/m_21/view.do?seq=12928
- Ha, K., Joung, H., Song, Y.J., Intake of dietary sugar and its influence on chronic disease in the korean population. Food Sci. Ind., 49, 1-11 (2016).
- World Health Organization, (2015, March 4). WHO calls on countries to reduce sugars intake among adults and children. Retrieved from https://www.who.int/news/item/04-03-2015-who-calls-on-countries-to-reduce-sugars-intake-among-adults-and-children
- Ministry of Health and Welfare, (2021, April 14). Press release - Practice healthy eating! The government announces 'Dietary Guidelines for Koreans'. Retrieved from http://www.mohw.go.kr/react/al/sal0301vw.jsp?PAR_MENU_ID=04&MENU_ID=0403&page=1&CONT_SEQ=365279
- Gupta, M., Sugar Substitutes: Mechanism, availability, current use and safety concerns-An update. Open Access Maced. J. Med. Sci., 6, 1888-1894 (2018).
- Roberts, M.W., Wright, J.T., Nonnutritive, low caloric substitutes for food sugars: clinical implications for addressing the incidence of dental caries and overweight/obesity. Int. J. Dent., 2012, 625701 (2012). https://doi.org/10.1155/2012/625701
- Durso, S.C., Vieiram L,M,, Cruzm J.N., Azevedo, C.S., Rodrigues, P.H., Simionato, M.R., Sucrose substitutes affect the cariogenic potential of Streptococcus mutans biofilms. Caries Res., 48, 214-222 (2014). https://doi.org/10.1159/000354410
- Forssten, S.D., Bjorklund, M., Ouwehand, A.C., Streptococcus mutans, caries and simulation models. Nutrients, 2, 290-298 (2010). https://doi.org/10.3390/nu2030290
- Park, J.H., Ahn, S.H., Gu, H.J., Choi, Y.H., Song, K.B., Inhibitory effects on colonization of Streptococcus mutans by eighteen months xylitol consumption. JKAIS, 11, 375-382 (2010).
- Janket, S.J., Benwait, J., Isaac, P., Ackerson, L.K., Meurman, J.H., Oral and systemic effects of xylitol consumption. Caries Res., 53, 491-501 (2019). https://doi.org/10.1159/000499194
- Duane, B., Xylitol and caries prevention. Evid. Based Dent., 16, 37-38 (2015). https://doi.org/10.1038/sj.ebd.6401088
- Riley, P., Moore, D., Ahmed, F., Sharif, M.O., Worthington, H.V., Xylitol-containing products for preventing dental caries in children and adults. Cochrane Database Syst. Rev., 26, CD010743 (2015).
- Ahmad, I., Shim, W.Y., Jeon, W.Y., Yoon, B.H., Kim, J.H., Enhancement of xylitol production in Candida tropicalis by co-expression of two genes involved in pentose phosphate pathway. Bioprocess Biosyst. Eng., 35, 199-204 (2012). https://doi.org/10.1007/s00449-011-0641-9
- Petkovic, M., 2019. Alternatives for sugar replacement in food technology: Formulating and processing key aspects. In: Coldea, T.E. (Ed), Food Engineering. IntechOpen, London, UK, pp. 1-22.
- Cannon, M.L., Merchant, M., Kabat, W., Catherine, L., White, K., Unruh, B., Ramones, A., In vitro studies of xylitol and erythritol inhibition of Streptococcus mutans and Streptococcus sobrinus growth and biofilm production. J. Clin. Pediatr. Dent., 44, 307-314 (2020). https://doi.org/10.17796/1053-4625-44.5.4
- Lee, Y.E., Choi, Y.H., Jeong, S.H., Kim, H.S., Lee, S.H., Song, K.B., Morphological changes in Streptococcus mutans after chewing gum containing xylitol for twelve months. Curr. Microbiol., 58, 332-337 (2009). https://doi.org/10.1007/s00284-008-9332-4
- Kim, H.D., An evaluation in changes of pH and dental caries activity in oral cavity due to dairy products. J. Korean Oral Health Sci., 5, 8-15 (2017).
- de Siqueira Fraga, E.G., Teofilo Campos, F.M., da Silva Cavalcante, M.P., Barbosa Martins, L.F., Rodrigues Neto, E.M., Jenne Mimica, M., Xylitol, a promising allied for oral heath. J. Young Pharm., 12, 197-200 (2020). https://doi.org/10.5530/jyp.2020.12.60
- Assev, S., Rolla, G., Further studies in the growth inhibition of Streptococcus mutans OMZ176 by xylitol. Acta Pathol. Microbiol. Immunol. Scand., 94, 97-102 (1986).
- Im, S.U., Ahn, S.H., Song, K.B., Comparison of virulence in xylitol-sensitive and -resistant Streptococcus mutans to different concentrations of xylitol. J. Dent. Hyg. Sci., 11, 411-416 (2011).
- Shin, K.H., Ahn, Y.S., A review of effect and how to use xylitol. J. Korean Soc. Dent. Hyg., 10, 1095-1105 (2010).
- Van Loveren, C., Sugar alcohols: what is the evidence for caries-preventive and caries-therapeutic effects? Caries Res., 38, 286-293 (2004). https://doi.org/10.1159/000077768
- Marttinen, A.M., Ruas-Madiedo, P., Hidalgo-Cantabrana, C., Saari, M.A., Ihalin, R.A., Soderling, E.M., Effects of xylitol on xylitol-sensitive versus xylitol-resistant Streptococcus mutans strains in a three-species in vitro biofilm. Curr. Microbiol., 65, 237-243 (2012). https://doi.org/10.1007/s00284-012-0151-2
- Murthykumar, K., The impact of milk with xylitol on dental caries. J. Pharm. Sci. Res., 5, 178-180 (2013).
- Nayak, P.A., Nayak, U.A., Khandelwal, V., The effect of xylitol on dental caries and oral flora. Clin. Cosmet. Investig. Dent., 6, 89-94 (2014).
- Ahuja, V., Macho, M., Ewe, D., Singh, M., Saha, S., Saurav, K., Biological and pharmacological potential of xylitol: A molecular insight of unique metabolism. Foods. 9, 1592 (2020). https://doi.org/10.3390/foods9111592
- Han, S.K., Choi, Y.H., Son, E.Y., Song, K.B., Kim, Y.G., Nam, S.H., Prevention of dental caries gum in pre-school children during 12-months. J. Korean Acad. Pediatr. Dent., 31, 159-168 (2004).
- Holgerson, P.L., Sjostrom, I., Twetman, S., Decreased salivary uptake of [14C]-xylitol after a four-week xylitol chewing gum regimen. Oral Health Prev. Dent., 5, 313-319 (2007).
- Makinen, K.K., Isotupa, K.P., Makinen, P.L., Soderling, E., Song, K.B., Nam, S.H., Jeong, S.H., Six-month polyol chewing-gum programme in kindergarten-age children: a feasibility study and dental plaque. Int. Dent. J., 55, 81-88 (2005). https://doi.org/10.1111/j.1875-595X.2005.tb00038.x
- Makinen, K.K., Alanen, P., Isokangas, P., Isotupa, K., Soderling, E., Makinen, P.L., Wenhui, W., Weijian, W., Xiaochi, C., Yi, W., Boxue, Z., Thirty- nine-month xylitol chewinggum programme in initially 8-year-old school children: a feasibility study focusing on mutans streptococci and lactobacilli. Int. Dent. J., 58, 41-50 (2008). https://doi.org/10.1111/j.1875-595x.2008.tb00175.x
- Chavan, S., Lakashminarayan, N., kemparaj, U., Effect of chewing xylitol containing and herbal chewing gums on salivary mutans streptococcus count among school children. Int. J. Prev. Med., 6, 44 (2015). https://doi.org/10.4103/2008-7802.157543
- Lee, Y.E., Kim, J.H., Cho, M.J., Song, K.B., Choi, Y.H., Effect of xylitol on dental caries prevention: a literature review. J. Korean Soc. Dent. Hyg., 19, 449-465 (2019). https://doi.org/10.13065/jksdh.20190041
- Milgrom, P., Ly, K.A., Roberts, M.E., Rothen, M., Mueller, G., Yamaguchi, D.K., Mutans streptococci dose response to xylitol chewing gum. J. Dent. Res., 8, 177-181 (2006).
- Ly, K.A., Riedy, C.A., Milgrom, P., Rothen, M., Roberts, M.C., Zhou, L., Xylitol gummy bear snacks: a school-based randomized clinical trial. BMC Oral Health, 8, 20 (2008). https://doi.org/10.1186/1472-6831-8-20
- Chi, D.L., Zegarra, G., Vasquez Huerta E.C., Castillo, J.L., Milgrom, P., Roberts, M.C., Cabrera-Matta, A.R., Merino, A.P., Milk sweetened with xylitol: A proof-of-principle caries prevention randomized clinical trial. J. Dent. Child. (Chic), 83, 152-160 (2016).
- Soderling, E., Pienihakkinen, K., Effects of xylitol chewing gum and candies on the accumulation of dental plaque: a systematic review. Clin. Oral Investig., 26, 119-129 (2022). https://doi.org/10.1007/s00784-021-04225-8
- Marya, C.M., Taneja, P., Nagpal, R., Marya, V., Oberoi, S.S., Arora, D., Efficacy of chlorhexidine, xylitol, and chlorhexidine + xylitol against dental plaque, gingivitis, and salivary Streptococcus mutans load: A randomised controlled trial. Oral Health Prev. Dent., 15, 529-536 (2017).
- Holgerson, P.L., Sjostrom, I., Stecksen-Blicks, C., Twetman, S., Dental plaque formation and salivary mutans streptococci in schoolchildren after use of xylitol-containing chewing gum. Int. J. Paediatr. Dent., 17, 79-85 (2007).
- Oza, S., Patel, K., Bhosale, S., Mitra, R., Gupta, R., Choudhary, D., To determine the effect of chewing gum containing xylitol and sorbitol on Mutans Streptococci and Lactobacilli count in saliva, plaque, and gingival health and to compare the efficacy of chewing gums. J. Int. Soc. Prev. Community Dent., 8, 354-360 (2018). https://doi.org/10.4103/jispcd.jispcd_54_18
- Burne, R.A., Marquis, R.E., Alkali production by oral bacteria and protection against dental caries. FEMS Microbiol. Lett., 193, 1-6 (2000). https://doi.org/10.1016/S0378-1097(00)00438-9
- Lee, S.H., Sakong, J. The effects of xylitol and sorbitol mouth rinse on caries activity. J. Korean Soc. Dent. Hyg., 15, 311-317 (2015). https://doi.org/10.13065/jksdh.2015.15.02.311
- Padminee, K., Poorni, S., Diana, D., Duraivel, D., Srinivasan, M.R., Effectiveness of casein phosphopeptide-amorphous calcium phosphate and xylitol chewing gums on salivary pH, buffer capacity, and Streptococcus mutans levels: An interventional study. Indian J. Dent. Res., 29, 616- 621 (2018). https://doi.org/10.4103/ijdr.ijdr_166_17
- Gul, P., Akgul, N., Seven, N., Anticariogenic potential of white cheese, xylitol chewing gum, and black tea. Eur. J. Dent., 12, 199-203 (2018). https://doi.org/10.4103/ejd.ejd_4_18
- Kumar, S., Sogi, S.H., Indushekar, K.R., Comparative evaluation of the effects of xylitol and sugar-free chewing gums on salivary and dental plaque pH in children. J. Indian Soc. Pedod. Prev. Dent., 31, 240-244 (2013). https://doi.org/10.4103/0970-4388.121822
- Stecksen-Blicks, C., Holgerson, P.L., Olsson, M., Bylund, B., Sjostrom, I., Skold-Larsson, K., Kalfas, S., Twetman, S., Effect of xylitol on Mutans streptococci and lactic acid formation in saliva and plaque from adolescents and young adults with fixed orthodontic appliances. Eur. J. Oral Sci., 112, 244-248 (2004). https://doi.org/10.1111/j.1600-0722.2004.00130.x
- Biria, M., Eslami, G., Taghipour, E., Akbarzadeh Baghban, A., Effects of three mastic gums on the number of Mutans streptococci, Lactobacilli and pH of the saliva. J. Dent., 11, 672-679 (2014).
- Song, K.B., Kim, J.H., Lee, Y.E., Prevention of mother-tochild transmission of Streptococcus mutans. JKDA, 48, 436- 442 (2010).
- Soderling, E., Isokangas, P., Pienihakkinen, K., Tenovuo, J., Influence of maternal xylitol consumption on acquisition of mutans streptococci by infants. J. Dent. Res., 79, 882-887 (2000). https://doi.org/10.1177/00220345000790031601
- Alamoudi, N.M., Hanno, A.G., Sabbagh, H.J., Masoud, M.I., Almushayt, A.S., El Derwi, D.A., Impact of maternal xylitol consumption on Mutans streptococci, plaque and caries levels in children. J. Clin. Pediatr. Dent., 37, 163-166 (2012). https://doi.org/10.17796/jcpd.37.2.261782tq73k4414x
- Lin, H.K., Fang, C.E., Huang, M.S., Cheng, H.C., Huang, T.W., Chang, H.T., Tam, K.W., Effect of maternal use of chewing gums containing xylitol on transmission of mutans streptococci in children: a meta-analysis of randomized controlled trials. Int. J. Paediatr. Dent., 26, 35-44 (2016). https://doi.org/10.1111/ipd.12155
- Hanno, A.G., Alamoudi, N.M., Almushayt, A.S., Masoud, M.I., Sabbagh, H.J., Farsi, N.M., Effect of xylitol on dental caries and salivary Streptococcus mutans levels among a group of mother-child pairs. J. Clin. Pediatr. Dent., 36, 25-30 (2011). https://doi.org/10.17796/jcpd.36.1.d4g77616714w3372
- Laitala, M.L., Alanen, P., Isokangas, P., Soderling, E., Pienihakkinen, K., Long-term effects of maternal prevention on children's dental decay and need for restorative treatment. Community Dent. Oral Epidemiol., 41, 534-540 (2013). https://doi.org/10.1111/cdoe.12057
- Kim, J.H., Lee, Y.E., Park, D.O., Ahn, S.H., Choi, Y.H., Song, K.B., Effect of maternal use of gums containing xylitol on the characteristics of Streptococcus mutans in children. J. Korean Acad. Oral Health, 34, 465-472 (2010).
- Shim, Y.S., An, S.Y., Park, S.Y., The effect of health risk factors on the remaining teeth of the elderly in day care center. Korean J.. Heal. Serv. Manag., 11, 81-91 (2017). https://doi.org/10.12811/kshsm.2017.11.2.081
- Roh, J.Y., Kim, K.R., Antimicrobial activity of Korean propolis extracts on oral pathogenic microorganisms. J. Dent. Hyg. Sci., 18, 18-23 (2018). https://doi.org/10.17135/jdhs.2018.18.1.18
- Nakagawa, K., Matsuo, K., Takagi, D., Morita, Y., Ooka, T., Hironaka, S., Mukai, Y., Effects of gum chewing exercises on saliva secretion and occlusal force in community-dwelling elderly individuals: A pilot study. Geriatr. Gerontol. Int., 17, 48-53 (2017). https://doi.org/10.1111/ggi.12670
- Simons, D., Brailsford, S., Kidd, E.A., Beighton, D., The effect of chlorhexidine acetate/xylitol chewing gum on the plaque and gingival indices of elderly occupants in residential homes. J. Clin. Periodontol., 28, 1010-1015 (2001). https://doi.org/10.1034/j.1600-051X.2001.281104.x
- Baik, S.H., The effects of xylitol and sorbitol on oral health and xerostomia in Korean elderly. J. Korean Gerontol. Nurs., 7, 88-103 (2005).
- Yuan, J., Tohara, H., Mikushi, S., Hoshino, T., Yue, B., Uematsu, H., The effect of "Oral Wet" for elderly people with xerostomia - the effect of oral rinse containing hialuronan. Kokubyo Gakkai Zasshi., 72, 106-110 (2005).
- Ship, J.A., McCutcheon, J.A., Spivakovsky, S., Kerr, A.R., Safety and effectiveness of topical dry mouth products containing olive oil, betaine, and xylitol in reducing xerostomia for polypharmacy-induced dry mouth. J. Oral Rehabil., 34, 724-732 (2007). https://doi.org/10.1111/j.1365-2842.2006.01718.x
- Morales-Bozo, I., Rojas, G., Ortega-Pinto, A., Espinoza, I., Soto, L., Plaza, A., Lozano, C., Urzua, B., Evaluation of the efficacy of two mouthrinses formulated for the relief of xerostomia of diverse origin in adult subjects. Gerodontology, 29, e1103-1112 (2012). https://doi.org/10.1111/j.1741-2358.2012.00626.x