한국미생물·생명공학회지 (Microbiology and Biotechnology Letters)

  • 제50권4호
  • /
  • Pages.465-476
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  • 2022
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  • 1598-642X(pISSN)
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  • 2234-7305(eISSN)
한국미생물·생명공학회 (The Korean Society for Microbiology and Biotechnology)
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Trends, Functionalities, and Prospects of Probiotics

  • Hyeon Ji, Jeon (School of Food Science and Biotechnology, Kyungpook National University) ;
  • O-Hyun, Ban (School of Food Science and Biotechnology, Kyungpook National University) ;
  • Won Yeong, Bang (Ildong Bioscience) ;
  • Jungwoo, Yang (Ildong Bioscience) ;
  • Young Hoon, Jung (School of Food Science and Biotechnology, Kyungpook National University)
  • 투고 : 2022.10.21
  • 심사 : 2022.12.02
  • 발행 : 2022.12.28
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초록

The importance of beneficial microorganisms, particularly probiotics, that coexist in the human body, is being increasingly recognized. Probiotics are representative health functional foods that provide health benefits to humans through the production of various metabolites, including short-chain fatty acids. However, the health benefits are strain-specific, and the use of each probiotic strain should follow guidelines that assure its safety. Accurate identification of the strain should be managed through genetic and phenotypic analyses of the strain. Besides, the functionality of probiotics should be disclosed in vitro and in vivo so that they can be used as legal functional ingredients (i.e., individual standards). In this review, we deal with the guidelines, including the technical factors related to probiotic strains. The common health effects of probiotic strains include proliferation of beneficial bacteria, control of harmful bacteria, and facilitation of bowel activities. Probiotics with various functionalities (e.g., body fat and cholesterol reduction, vaginal health, and improvement of skin's immune system) have been investigated as "individual standards of raw materials for health functional foods" provided by MFDS. In the future, various biotechnologies including synthetic biology can be applied to produce customized probiotics to improve human health.

키워드

과제정보

This research was supported by Kyungpook National University Development Project Research Fund, 2021.

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