과제정보
본 연구는 한국연구재단의 우수신진연구(No. NRF-2021R1C1C100506211)의 사업비로 수행되었음.
참고문헌
- Siegel RL, Miller KD, Fuchs HE, Jemal A. Cancer statistics, 2022. CA Cancer J Clin. 2022;72(1):7-33. https://doi.org/10.3322/caac.21708
- Statistics Korea. Available from: http://www.index.go.kr/ potal/main/EachDtlPageDetail.do?idx_cd=2770
- Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell. 2011;144(5):646-74. https://doi.org/10.1016/j.cell.2011.02.013
- Nagy JA, Chang SH, Shih SC, Dvorak AM, Dvorak HF. Heterogeneity of the tumor vasculature. Semin Thromb Hemost. 2010;36:321-31.
- Baluk P, Hashizume H, McDonald DM. Cellular abnormalities of blood vessels as targets in cancer. Curr Opin Genet Dev. 2005;15:102-11. https://doi.org/10.1016/j.gde.2004.12.005
- Prager GW, Poettler M. Angiogenesis in cancer. Basic mechanisms and therapeutic advances. Hamostaseologie. 2012;32(2):105-14. https://doi.org/10.5482/ha-1163
- The Jointly Published Textbook Compilation Committee of Oriental College of Medicine Nationwide Department. Herbology. Seoul: Younglim press; 2004.
- Hou Z, Zhu L, Meng R, Wang B. Hypolipidemic and antioxidant activities of Trichosanthes kirilowii maxim seed oil and flavonoids in mice fed with a high-fat diet. J Food Biochem. 2020;44(8):e13272. https://doi.org/10.1111/jfbc.13376
- Hu Z, Zhou H, Zhao J, Sun J, Li M, Sun X. Microwave-assisted extraction, characterization and immunomodulatory activity on RAW264.7 cells of polysaccharides from Trichosanthes kirilowii Maxim seeds. Int J Biol Macromol. 2020;164:2861-72. https://doi.org/10.1016/j.ijbiomac.2020.08.072
- Park SM, Jeon SK, Kim OH, Ahn JY, Kim CH, Park SD, Lee JH. Anti-tumor effects of the ethanolic extract of Trichosanthes kirilowii seeds in colorectal cancer. Chin Med. 2019;14:43.
- Maj E, Papiernik D, Wietrzyk J. Antiangiogenic cancer treatment: the great discovery and greater complexity (Review). Int J Oncol. 2016;49:1773-84. https://doi.org/10.3892/ijo.2016.3709
- Kendall RL, Wang G, DiSalvo J, Thomas KA. Specificity of vascular endothelial cell growth factor receptor ligand binding domains. Biochem Biophys Res Commun. 1994; 201:326-30. https://doi.org/10.1006/bbrc.1994.1705
- Olsson AK, Dimberg A, Kreuger J, Claesson-Welsh L. VEGF receptor signalling - in control of vascular function. Nat Rev Mol Cell Biol. 2006;7:359-71. https://doi.org/10.1038/nrm1911
- Lamalice L, Le Boeuf F, Huot J. Endothelial cell migration during angiogenesis. Circ Res. 2007;100(6):782-94. https://doi.org/10.1161/01.RES.0000259593.07661.1e
- Katoh M. FGFR inhibitors: Effects on cancer cells, tumor microenvironment and whole-body homeostasis (Review). Int J Mol Med. 2016;38(1):3-15. https://doi.org/10.3892/ijmm.2016.2620
- Parmar D, Apte M. Angiopoietin inhibitors: A review on targeting tumor angiogenesis. Eur J Pharmacol. 2021;899:174021.
- Nguyen QD, De Falco S, Behar-Cohen F, Lam WC, Li X, Reichhart N, Ricci F, Pluim J, Li WW. Placental growth factor and its potential role in diabetic retinopathy and other ocular neovascular diseases. Acta Ophthalmol. 2018;96(1):e1-e9.
- Ostman A. PDGF receptors-mediators of autocrine tumor growth and regulators of tumor vasculature and stroma. Cytokine Growth Factor Rev. 2004;15(4):275-86. https://doi.org/10.1016/j.cytogfr.2004.03.002
- Gao X, Xu Z. Mechanisms of action of angiogenin. Acta Biochim Biophys Sin (Shanghai). 2008;40(7):619-24. https://doi.org/10.1111/j.1745-7270.2008.00442.x
- Ogami K, Yamaguchi R, Imoto S, Tamada Y, Araki H, Print C, Miyano S. Computational gene network analysis reveals TNF-induced angiogenesis. BMC Syst Biol. 2012;6 Suppl 2(Suppl 2):S12.
- LI X, Zhao A, Yang J, Qian J, Chen L. Study on Role of Mucin 5AC in Malignant Tumors Based on Theory of "Body Fluid" and "Phlegm and Retained Fluid". Liaoning J Trad Chin Med. 2020;8:51-4.
- Li Y, Li D, Chen J, Wang S. A polysaccharide from Pinellia ternata inhibits cell proliferation and metastasis in human cholangiocarcinoma cells by targeting of Cdc42 and 67kDa Laminin Receptor (LR). Int J Biol Macromol. 2016;93(Pt A):520-5. https://doi.org/10.1016/j.ijbiomac.2016.08.069
- Hosny S, Sahyon H, Youssef M, Negm A. Prunus Armeniaca L. Seed Extract and Its Amygdalin Containing Fraction Induced Mitochondrial-Mediated Apoptosis and Autophagy in Liver Carcinogenesis. Anticancer Agents Med Chem. 2021;21(5):621-9. https://doi.org/10.2174/1871520620666200608124003
- Kim DW, Lee JH, Yoo HS, Cho JH, Lee YW, Son CH, Cho CK. Effects of Trichosanthes kirilowii Extract against Angiogenesis and Various Tumor Cells' Growth. Korean J Orient Int Med. 2008;29(2):490-9.
- Hwang WK. Identification for TLC pattern analysis of the crude drugs (II). Ministry of Food and Drug Safety. 2013. p28
- Zhoh CK, Uhm TY, Kim JC. Antioxidantive Effectiveness of Trichosanthes Kirilowill Maximowicz Extracts, J Korean Ind Eng Chem, Vol18, No. 6, 2007, 625-9.
- Dat NT, Jin X, Hong YS, Lee JJ. An isoaurone and other constituents from Trichosanthes kirilowii seeds inhibit hypoxia-inducible factor-1 and nuclear factor-kappaB. J Nat Prod. 2010;73(6):1167-9. https://doi.org/10.1021/np900820p
- Ye X, Ng CC, Wong JH, Ng TB, Chan GH, Guan S, et al. Ribosome-inactivating Proteins from Root Tubers and Seeds of Trichosan-thes kirilowii and Other Trichosanthes Species. Protein Pept Lett. 2016;23(8):699-706. https://doi.org/10.2174/0929866523666160526130220
- He D, Jin J, Zheng Y, Bruce IC, Tam S, Ma X. Anti-angiogenesis effect of trichosanthin and the underlying mechanism. Biochem Biophys Res Commun. 2013;430(2):735-40. https://doi.org/10.1016/j.bbrc.2012.11.080