Journal of Korean Biological Nursing Science

  • 제24권4호
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  • Pages.235-242
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  • 2022
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  • 2383-6415(pISSN)
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  • 2383-6423(eISSN)
한국기초간호학회 (Korean society of Biological Nursing Science)
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지역사회 거주 성인의 지각된 스트레스, 혈중 코티졸 수준 및 텔로미어 길이의 관련성

Associations of Perceived Stress Level, Serum Cortisol Level, and Telomere Length of Community-dwelling Adults in Korea

  • Kim, A Young (Department of Nursing, Graduate School of Keimyung University) ;
  • Kim, Nahyun (College of Nursing, Keimyung University)
  • 투고 : 2022.09.17
  • 심사 : 2022.11.23
  • 발행 : 2022.11.30
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초록

Purpose: To investigate associations of perceived stress level, serum cortisol level, and telomere length of community-dwelling adults in Korea. Methods: Data of a total of 135 community-dwelling adults aged over 40 years living in D metropolitan city from December 2020 to March 2021 were collected. Perceived stress level over the past month were measured using the Perceived Stress Score. Serum cortisol level was analyzed using a chemiluminescent microparticle immunoassay. Telomere length was determined using quantitative real-time polymerase chain reaction. The statistical package SPSS 23.0 was used to perform Chi-square test, independent t-test, and Pearson's correlation coefficient analysis. Results: There was no association between perceived stress and serum cortisol level (r = .07, p= .402). Serum cortisol level was not significantly associated with telomere length either (r = -.15, p= .081). However, the higher the perceived stress level, the shorter the telomere length (r= -.29, p= .001). Conclusion: These results suggest that perceived stress might induce physiological stress, which might partially affect gene biology. Further longitudinal research is needed to investigate the effect of perceived stress on telomere length. Intervention for relieving stress should be included in stabilizing the genetic environment of adults.

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과제정보

이 논문은 정부(과학기술정보통신부)의 재원으로 한국연구재단의 지원을 받아수행된 연구임(No. 2020R1A2C1006590).

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