농업과학연구 (Korean Journal of Agricultural Science)

  • 제49권3호
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  • Pages.389-396
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  • 2022
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  • 2466-2402(pISSN)
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  • 2466-2410(eISSN)
충남대학교 농업과학연구소 (Institute of Agricultural Science, CNU)
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Effect of drinking Houttuynia cordata Thunb extract supplement on growth performance and colony count outcomes in ICR mice

  • Jae Woo, An (Department of Animal Science, Chungbuk National University) ;
  • Sung Bo, Cho (Traditional Mongolian Medicine Research Institute, Inner Mongolia University for Nationalities) ;
  • Ji Hwan, Lee (Department of Animal Science, Chungbuk National University) ;
  • Han Jin, Oh (Department of Animal Science, Chungbuk National University) ;
  • Yong Ju, Kim (Department of Animal Science, Chungbuk National University) ;
  • Se Yeon, Chang (Department of Animal Science, Chungbuk National University) ;
  • Young Bin, Go (Department of Animal Science, Chungbuk National University) ;
  • Dong Cheol, Song (Department of Animal Science, Chungbuk National University) ;
  • Hyun Ah, Cho (Department of Animal Science, Chungbuk National University) ;
  • Jin Ho, Cho (Department of Animal Science, Chungbuk National University)
  • 투고 : 2022.01.20
  • 심사 : 2022.05.10
  • 발행 : 2022.09.01
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초록

The purpose of this study was to investigate the safety of Houttuynia cordata Thunb extract (HCE) in Institute of Cancer Research (ICR) mice, to determine the effects of the extract on the growth performance and colony count, and to establish the optimal concentration of HCE. In total, 60 five-week-old male ICR mice with an average initial body weight (BW) of 27.24 ± 0.44 g were used in a four-week experiment. Mice were randomly allotted to four treatment groups (five replications per group, three mice per cage): 1) a control (CON) group fed with normal distilled water; 2) treatment group 1 (T1) fed with normal distilled water containing 0.05% HCE; 3) treatment group 3 (T3) fed with normal distilled water containing 0.1% HCE; and 4) treatment group 3 (T3) fed with normal distilled water containing 0.2% HCE. BW, feed intake (FI), and water intake were measured on the first, fourteenth, and eighteenth days. T2 showed a significant improvement (p < 0.05) in the feed conversion ratio (FCR) over the experimental period. However, water intake levels did not show significant differences among the groups. In the large intestine and feces, E. coli and Lactobacillus levels were significantly improved (p < 0.05) in the HCE treated group compared to the CON group. Supplying HCE via the drinking water improved the growth performance and colony count in ICR mice. Based on results of this study, utilizing HCE in livestock species is expected to be safe and feasible.

키워드

과제정보

Following are results of a study on the "Leaders in Industry-university Cooperation +" Project, supported by the Ministry of Education and National Research Foundation of Korea.

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