International Journal of Oral Biology

  • 제47권4호
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  • Pages.49-54
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  • 2022
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  • 1226-7155(pISSN)
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  • 2287-6618(eISSN)
대한구강생물학회 (The Korean Academy of Oral Biology)
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Salty taste: the paradoxical taste

  • In-Sun, Choi (Department of Physiology and Neuroscience, College of Dentistry, Gangneung-Wonju National University) ;
  • Kyung-Nyun, Kim (Department of Physiology and Neuroscience, College of Dentistry, and Research Institute of Oral Sciences, Gangneung-Wonju National University)
  • 투고 : 2022.12.06
  • 심사 : 2022.12.12
  • 발행 : 2022.12.22
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초록

Taste is a basic sensation to get attracted toward nutritious foods or avoid possible harmful substances. The basic taste qualities in humans consist of sweet, bitter, umami, salty, and sour. Basically, sweet and umami tastes make food attractive, whereas bitter and sour tastes make it avoidable. Salty taste comprises basic salty and high salt taste. The basic salty taste is known as amiloride-sensitive salty taste, which is inhibited by amiloride, but the high salt taste is not sensitive to amiloride. Moreover, high salt taste can also cause avoidance behavior in human beings. Sodium, one of the most important cations in the body fluids of vertebrates, controls the volume of total body fluids and is a risk factor for cardiovascular diseases, such as hypertension. The concentration of sodium in body fluids must be under delicate control. A distinction between the salty taste and high salt taste would be a contributing mechanism to control the volume and/or osmolarity of body fluids.

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과제정보

The work is supported by Basic science Research Program through the National Research Foundation in Korea (NRF) funded by the Ministry of Science and ICT (2020R1F1A1049633).

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