Clinical and Experimental Pediatrics

대한소아청소년과학회 (The Korean Pediatric Society)
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Prevalence of methicillin-resistant Staphylococcus aureus in Iranian children: a systematic review and meta-analysis

  • Sarrafzadeh, Farhad (Faculty of Medicine, Kerman University of Medical Sciences) ;
  • Sohrevardi, Seyed Mojtaba (Pharmaceutical Science Research Center, Faculty of pharmacy, Shahid Sadoughi University of Medical Science) ;
  • Abousaidi, Hamid (Faculty of Medicine, Kerman University of Medical Sciences) ;
  • Mirzaei, Hossein (HIV/STI Surveillance Research Center, WHO Collaborating Center for HIV Surveillance, Institute for Futures Studies in Health, Kerman University of Medical Sciences)
  • 투고 : 2020.02.24
  • 심사 : 2020.10.22
  • 발행 : 2021.08.15
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초록

Background: Antibiotic resistance is associated with longer hospitalizations, higher treatment costs, and increased morbidity and mortality rates. Purpose: This study aimed to determine the prevalence of methicillin-resistant Staphylococcus aureus (MRSA) in Iranian children. Methods: International databases, including Web of Science, PubMed, Embase, and Scopus, and Iranian databases, including Scientific Information Database (www.sid.ir), Magiran, and Iranian Database for Medical Literature (idml.research.ac.ir), were systematically searched for articles published between January 2000 and August 2019. Sources of heterogeneity were determined using subgroup analysis and meta-regression. Results: Overall, 343 studies were identified; of them, 20 were included in the meta-analysis to estimate the pooled prevalence. The pooled prevalence of MRSA was 42% (95% confidence interval [CI], 29-55) among culture-positive cases of S. aureus, 51% (95% CI, 39-62) in hospitalized children, and 14% (95% CI, 0.05-27) in healthy children. Conclusion: The overall pooled prevalence of MRSA in children was 42%. Appropriate infection control measures and effective antibiotic therapy are needed.

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참고문헌

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피인용 문헌

  1. Staphylococcus aureus Bacteremia in Hospitalized Patients and Associated Factors: A Cross-sectional Study from Mashhad, Iran vol.14, pp.7, 2021, https://doi.org/10.5812/jjm.116313