Journal of Industrial Convergence (산업융합연구)

DAEHAN Society of Industrial Management (대한산업경영학회)
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Association of vitamin E levels with metabolic syndrome, and metabolic syndrome components among adults

성인의 비타민E 수준에 따른 대사증후군 및 대사증후군 요인과의 연관성

  • Received : 2021.07.22
  • Accepted : 2021.10.20
  • Published : 2021.10.31
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Abstract

This study identified vitamin E associated with metabolic syndrome and metabolic syndrome components among Korean adults aged over 19 years. Secondary data from the 2016-2018 Korean National Health and Nutrition Examination Survey were used for this study. Data from 6,425 were analyzed by logistic regression analysis using a complex sample procedure. As a result of logistic regression analysis, the odds ratio was increased in the group with high vitamin E levels compared to the group with normal vitamin E levels. There are metabolic syndrome (Adjusted Odds Ratio [AOR]: 1.889, 95% Confidence Interval [CI]: 1.550-2.303, p<.001), abdominal obesity (AOR: 1.444, CI: 1.205-1.730, p<.001), hyperglyceridemia(AOR: 3.182, CI: 2.641-3.835, p<.001), systolic blood pressure (AOR: 1.711, CI: 1.446-2.026, p<.001), diastolic blood pressure (AOR: 1.806, CI: 1.521-2.144, p<.001), low high density lipoprotein cholesterol (AOR: 1.558, CI: 1.060-2.290, p=.024). Therefore vitamin E was associated with metaboic syndrome and metabolic syndrome components. So when providing nursing intervention for people with metabolic syndrome, education on vitamin E should be actively included.

본 연구는 19세 이상 성인에서 비타민E와 대사증후군 및 대사증후군 요인과의 관계를 알아보기 위한 연구로 제7기 국민건강영양조사 원시자료를 활용한 단면조사 연구이다. 자료는 IBM SPSS Statistics 24.0을 이용하여 가중치를 적용한 복합표본설계로 Chi-sqaure, t-test, ANOVA, 로지스틱회귀분석을 실시하였다. 자료분석에 포함된 전체 대상자는 6,425명으로 ABIM (American Bord of Internal Medicine) laboratory reference range에 따라 비타민E 수준을 높음, 정상, 낮음으로 구분하였다. 비타민E가 높은 그룹 882명, 정상 그룹 5,498명, 낮은 그룹 45명이었다. 로지스틱회귀분석 결과 비타민E 수준이 정상인 그룹에 비하여 높은 그룹이 대사증후군(Adjusted Odds Ratio [AOR]: 1.889, 95% Confidence Interval [CI]: 1.550-2.303, p<.001), 복부비만(AOR: 1.444, CI: 1.205-1.730, p<.001), 고중성지방(AOR: 3.182, CI: 2.641-3.835, p<.001), 수축기혈압(AOR: 1.711, CI: 1.446-2.026, p<.001), 이완기기혈압(AOR: 1.806, CI: 1.521-2.144, p<.001), 저고밀도지단백콜레스테롤(AOR: 1.558, CI: 1.060-2.290, p=.024)의 오즈비가 증가함을 보였다. 본 연구 결과는 비타민E와 대사증후군 및 대사증후군 요인과 연관성이 있음을 나타내므로 대사증후군 대상자 간호중재 시 비타민E에 대한 교육이 적극적으로 포함되어야 할 것으로 생각된다.

Keywords

References

  1. S. M. Grundy. (2005). Diagnosis and management of the metabolic syndrome: an American Heart Association/National Heart, Lung, and Blood Institute scientific statement. Circulation, 112(17), 2735-2752. DOI : 10.1161/CIRCULATIONAHA.105.169404
  2. J. H. Huh, D. R. Kang, J. Y. Kim & K. K. Koh. (2021). Metabolic Syndrome Fact Sheet 2021: Executive Report. CardioMetabolic Syndrome Journal, 1(12), e15. DOI : 10.51789/cmsj.2021.1.e15
  3. G. Hirode & R. J. Wong. (2020). Trends in the prevalence of metabolic syndrome in the United States, 2011-2016. Jama, 323(24), 2526-2528. DOI : 10.1001/jama.2020.4501
  4. P. Ranasinghe, Y. Mathangasinghe, R. Jayawardena, A. Hills & A. Misra. (2017). Prevalence and trends of metabolic syndrome among adults in the asia-pacific region: a systematic review. BMC public health, 17(1), 1-9. DOI : 10.1186/s12889-017-4041-1
  5. M. H. Kim et al. (2020). The change of metabolic syndrome prevalence and its risk factors in Korean adults for decade: Korea National Health and Nutrition Examination Survey for 2008-2017. Korean Journal of Family Practice, 10(1), 44-52. DOI : 10.21215/kjfp.2020.10.1.44
  6. P. Prasad & A. Kochhar. (2016). Interplay of vitamin D and metabolic syndrome: a review. Diabetes & Metabolic Syndrome: Clinical Research & Reviews, 10(2), 105-112. DOI : 10.1016/j.dsx.2015.02.014
  7. S. K. Wong, K. Y. Chin, F. H. Suhaimi, F. Ahmad & S. Ima-Nirwana. (2017). Vitamin E as a potential interventional treatment for metabolic syndrome: evidence from animal and human studies. Frontiers in pharmacology, 8, 444. DOI : 10.3389/fphar.2017.00444
  8. S. H. Cho. (2010). Vitamin E: α-Tocopherol and the Other Forms of Vitamin E. Journal of Nutrition and Health, 43(3), 304-314. DOI : 10.4163/kjn.2010.43.3.304
  9. A. Suychinov et al. (2019). Vitamins and their role in human body. International Journal of Pharmaceutical Research, 11(3), 1246-1248. DOI : 10.31838/ijpr/2019.11.03.018
  10. G. F. Ball. (2008). Vitamins: their role in the human body: John Wiley & Sons.
  11. K. Heng, A. Hejar, S. J. Johnson, C. Ooi & S. Loh. (2015). Potential of mixed tocotrienol supplementation to reduce cholesterol and cytokines level in adults with metabolic syndrome. Malaysian Journal of Nutrition, 21(2), 231-243.
  12. M. Rafraf, B. Bazyun, M. A. Sarabchian, A. Safaeiyan & S. J. G. Hezaveh. (2012). Impact of vitamin E supplementation on blood pressure and Hs-CRP in type 2 diabetic patients. Health promotion perspectives, 2(1), 72-69.
  13. M. Godala et al. (2016). Lower plasma levels of antioxidant vitamins in patients with metabolic syndrome: A case control study. Advances in Clinical and Experimental Medicine, 25(4), 689-700. DOI : 10.17219/acem/41049
  14. S. U. Ahn et al. (2017). Association between intake of antioxidant vitamins and metabolic syndrome risk among Korean adults. Journal of Nutrition and Health, 50(4), 313-324. DOI : 10.4163/jnh.2017.50.4.313
  15. A. B, Jain & Jain, V. A. (2012). Vitamin E, its beneficial role in diabetes mellitus (DM) and its complications. Journal of clinical and diagnostic research: JCDR, 6(10), 1624-1628. DOI : 10.7860/JCDR/2012/4791.2625
  16. Z. A. Mahdy. (2015). Does palm oil vitamin E reduce the risk of pregnancy induced hypertension? Acta Medica, 56(3), 104-109. DOI : 10.14712/18059694.2014.17
  17. K. Alberti et al. (2009). Harmonizing the metabolic syndrome: a joint interim statement of the international diabetes federation task force on epidemiology and prevention; national heart, lung, and blood institute; American heart association; world heart federation; international atherosclerosis society; and international association for the study of obesity. Circulation, 120(16), 1640-1645. DOI : 10.1161/CIRCULATIONAHA.109.192644
  18. S. Waniek et al. (2017). Association of vitamin E levels with metabolic syndrome, and MRI-derived body fat volumes and liver fat content. Nutrients, 9(10), 1143. DOI : 10.3390/nu9101143
  19. M. Vafa, N. Haghighat, N. Moslehi, S. Eghtesadi & I. Heydari. (2015). Effect of Tocotrienols enriched canola oil on glycemic control and oxidative status in patients with type 2 diabetes mellitus: A randomized double-blind placebo-controlled clinical trial. Journal of research in medical sciences: the official journal of Isfahan University of Medical Sciences, 20(6), 540-547. DOI : 10.4103/1735-1995.165945
  20. M. A. Beydoun, M. R. Shroff, X. Chen, H. A. Beydoun, Y. Wang & A. B. Zonderman. (2011). Serum antioxidant status is associated with metabolic syndrome among US adults in recent national surveys. The Journal of nutrition, 141(5), 903-913. DOI : 10.3945/jn.110.136580.
  21. M. K. Kim et al. (2014). 2014 clinical practice guidelines for overweight and obesity in Korea. Endocrinology and Metabolism, 29(4), 405-409. DOI : 10.3803/EnM.2014.29.4.405
  22. D. J. Levinson, (1986). A conception of adult development. American psychologist, 41(1), 3-13. https://doi.org/10.1037//0003-066X.41.1.3
  23. ABIM. (2021). ABIM laboratory reference rages. Philadelphia: American Board of Internal Medicine(0nline). [cited 2021July 20]. Available from: https://www.abim.org/Media/bfijryql/laboratory-reference-ranges.pdf
  24. M. R. Emami, M. Safabakhsh, S. Alizadeh, O. Asbaghi & M. Z. Khosroshahi. (2019). Effect of vitamin E supplementation on blood pressure: a systematic review and meta-analysis. Journal of human hypertension, 33(7), 499-507. DOI : 10.1038/s41371-019-0192-0
  25. K. P. Kim, J. H. Choi & S. B. Pak. (2021). Association between Vitamin A, E and Type2 Diabetes Mellitus in Korea: Korean National Health and Nutrition Examination Survey 2016-2018. Korean Journal of Family Practice, 11(2), 135-141. DOI :10.21215/kjfp.2021.11.2.135.
  26. A. S. Wedell-Neergaard. (2019). Exercise-induced changes in visceral adipose tissue mass are regulated by IL-6 signaling: a randomized controlled trial. Cell metabolism, 29(4), 844-855. DOI : 10.1016/j.cmet.2018.12.007
  27. G. A. Lee, H. Y. Choi & S. J. Yang. (2015). Effects of Dietary and Phycal Activity Interventions on Metabolic Syndrome: A Meta-analysis. Journal of Korea Academic Nursing. 45(4), 484-494. DOI : 10.4040/jkan.2015.45.4.483