대한두개안면성형외과학회지 (Archives of Craniofacial Surgery)

  • 제22권5호
  • /
  • Pages.254-259
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  • 2021
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  • 2287-1152(pISSN)
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  • 2287-5603(eISSN)
대한두개안면성형외과학회 (Korean Cleft Palate-Craniofacial Association)
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Antibiotic use in nasal bone fracture: a nationwide population-based cohort study in Korea

  • Jeon, Yeo Reum (Department of Plastic and Reconstructive Surgery, National Health Insurance Service Ilsan Hospital) ;
  • Jung, Ji Hyuk (Department of Plastic and Reconstructive Surgery, National Health Insurance Service Ilsan Hospital) ;
  • Song, Joon Ho (Department of Plastic and Reconstructive Surgery, National Health Insurance Service Ilsan Hospital) ;
  • Chung, Seum (Department of Plastic and Reconstructive Surgery, National Health Insurance Service Ilsan Hospital)
  • 투고 : 2021.08.20
  • 심사 : 2021.10.12
  • 발행 : 2021.10.20
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초록

Background: Prophylactic antibiotics are commonly used in craniofacial surgeries. Despite the low risk of surgical site infection after nasal surgery, a lack of consensus regarding the use of antibiotic prophylaxis in the closed reduction of nasal bone fractures has led to inappropriate prescribing patterns. Through this study, we aimed to investigate the status of prophylactic antibiotic use in closed reductions of nasal bone fractures in Korea. Methods: This retrospective cohort study was conducted using data from the National Health Insurance Service-National Sample Cohort of Korea from 2005 to 2015. We analyzed the medical records of patients who underwent closed reduction of nasal bone fractures. The sex, age, region of residence, comorbidities, and socioeconomic variables of the patients were collected from the database. Factors that affect the prescription of perioperative antibiotics were evaluated using multivariate logistic regression analysis. Results: A total of 3,678 patients (mean±standard deviation of age, 28.7±14.9 years; 2,850 men [77.5%]; 828 women [22.5%]) were included in this study. The rate of antibiotic prescription during the perioperative period was 51.4%. Approximately 68.8% of prescriptions were written for patients who had received general anesthesia. The odds of perioperative prophylactic antibiotic use were significantly higher in patients who received general anesthesia than who received local anesthesia (odds ratio, 1.59). No difference was found in terms of patient age and physician specialty. Second-generation cephalosporins were the most commonly prescribed antibiotic (45.3%), followed by third- and first-generation cephalosporins (20.3% and 18.8%, respectively). In contrast, lincomycin derivatives and aminoglycosides were not prescribed. Conclusion: The findings of this study showed that there was a wide variety of perioperative antibiotic prescription patterns used in nasal bone surgeries. Evidence-based guidance regarding the prescribing of antimicrobial agents for the closed reduction of nasal bone fractures should be considered in future research.

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과제정보

This work was supported by National Health Insurance Service Ilsan Hospital (grant No. NHIMC2021-CR-047).

참고문헌

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