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Isolation and Quantitative Analysis of Chemical Constituents in Codonopsis lanceolata

  • Ju, Yeongdon (Department of Clinical Laboratory Science, College of Health Sciences, Catholic University of Pusan) ;
  • Jeon, Jeong Wook (Nutricare Co Ltd) ;
  • Hyun, Kyung-Yae (Department of Clinical Laboratory Science, Dong-Eui University)
  • Received : 2021.08.13
  • Accepted : 2021.09.14
  • Published : 2021.09.30

Abstract

Codonopsis lanceolata has numerous chemical constituents that includes polyphenols, saponins, tannins, triterpene, alkaloids, and steroids. The extract of C. lanceolata was partitioned with Haxane, CH2Cl2, EtOAc, n-BuOH and MeOH. The determination of structure for lancemaside G, lancemaside B, lancemaside A were based on physicochemical and HPLC chromatogram data, including NMR and HR-MS. In addition, tangshenoside I and lobetyolin were identified in the material separation process for the extract of C. lanceolata, and content analysis was performed using HPLC. The compounds were confirmed as lancemaside G, lancemaside B, lancemaside A, tangshenoside I, and lobetyolin.

Keywords

Acknowledgement

This research was supported by 2020 Regional Specialized Industry Promotion (Non-R&D) Project of Hongcheon Institute of Medicinal Herb (HIMH) and Brain Busan 21 Plus (BB21+) Project.

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