Investigative Magnetic Resonance Imaging

Korean Society of Magnetic Resonance in Medicine (대한자기공명의과학회)
권호 표지
DOI QR코드

DOI QR Code

High-Grade Mucoepidermoid Carcinoma Ex Metastasizing Pleomorphic Adenomas in the Parotid Gland and Parapharyngeal Space: a Case Report and Literature Review

  • Lee, Eun Ji (Department of Radiology, University of Inha College of Medicine) ;
  • Lee, Ha Young (Department of Radiology, University of Inha College of Medicine) ;
  • Choi, Suk Jin (Department of Pathology, University of Inha College of Medicine) ;
  • Lim, Myung Kwan (Department of Radiology, University of Inha College of Medicine) ;
  • Kang, Young Hye (Department of Radiology, University of Inha College of Medicine)
  • Received : 2021.06.13
  • Accepted : 2021.08.02
  • Published : 2021.09.30
Download PDF
⟨ Previous Next ⟩

Abstract

Pleomorphic adenoma is the most common benign neoplasm of the salivary glands. Its three malignant variants include carcinoma ex pleomorphic adenoma, carcinosarcoma, and metastasizing pleomorphic adenoma. Among the subtypes of carcinoma ex pleomorphic adenoma, high-grade mucoepidermoid carcinoma has rarely been reported. Additionally, metastasizing pleomorphic adenoma is rare. We report the imaging findings of a high-grade mucoepidermoid carcinoma ex metastasizing pleomorphic adenoma of the parotid gland and parapharyngeal space in a 42-year-old man.

Keywords

References

  1. Knight J, Ratnasingham K. Metastasising pleomorphic adenoma: systematic review. Int J Surg 2015;19:137-145 https://doi.org/10.1016/j.ijsu.2015.04.084
  2. Pollack AZ, Paul BC, Sheu MC, Har-El G. High-grade mucoepidermoid carcinoma ex-pleomorphic adenoma of the parotid gland: case report and review of literature. Int J Otolaryngol Head Neck Surg 2014;3:9-13 https://doi.org/10.4236/ijohns.2014.31003
  3. Stanley MW, Lowhagen T. Mucin production by pleomorphic adenomas of the parotid gland: a cytologic spectrum. Diagn Cytopathol 1990;6:49-52 https://doi.org/10.1002/dc.2840060111
  4. Jacobs JC. Low grade mucoepidermoid carcinoma ex pleomorphic adenoma. A diagnostic problem in fine needle aspiration biopsy. Acta Cytol 1994;38:93-97
  5. Pitman MB. Mucoepidermoid carcinoma ex pleomorphic adenoma of the parotid gland. Acta Cytol 1995;39:604-606
  6. Klijanienko J, El-Naggar AK, Servois V, Rodriguez J, Validire P, Vielh P. Mucoepidermoid carcinoma ex pleomorphic adenoma: nonspecific preoperative cytologic findings in six cases. Cancer 1998;84:231-234 https://doi.org/10.1002/(SICI)1097-0142(19980825)84:4<231::AID-CNCR8>3.0.CO;2-P
  7. Daniel L, Rao S, Muthusamy R, Yerramsetti D. Mucoepidermoid carcinoma ex pleomorphic adenoma of the lacrimal gland: a rare presentation. Indian J Ophthalmol 2014;62:743-746 https://doi.org/10.4103/0301-4738.136281
  8. Sload RL, Carbone P, Johnson C, Johnson T. Carcinoma ex pleomorphic adenoma of the parotid gland. Acta Otolaryngol Case Rep 2016;1:7-70
  9. Czader M, Eberhart CG, Bhatti N, Cummings C, Westra WH. Metastasizing mixed tumor of the parotid: initial presentation as a solitary kidney tumor and ultimate carcinomatous transformation at the primary site. Am J Surg Pathol 2000;24:1159-1164 https://doi.org/10.1097/00000478-200008000-00015
  10. Fujimura M, Sugawara T, Seki H, et al. Carcinomatous change in the cranial metastasis from a metastasizing mixed tumor of the salivary gland--case report. Neurol Med Chir (Tokyo) 1997;37:546-550 https://doi.org/10.2176/nmc.37.546
  11. Minic AJ. Unusual variant of a metastasizing malignant mixed tumor of the parotid gland. Oral Surg Oral Med Oral Pathol 1993;76:330-332 https://doi.org/10.1016/0030-4220(93)90262-3
  12. Kato H, Kanematsu M, Mizuta K, Ito Y, Hirose Y. Carcinoma ex pleomorphic adenoma of the parotid gland: radiologicpathologic correlation with MR imaging including diffusion-weighted imaging. AJNR Am J Neuroradiol 2008;29:865-867 https://doi.org/10.3174/ajnr.A0974
  13. Kim TK, Kim HY, Yu IK, Son HJ, Chang DS, Jang YD. Schwannoma of the tongue base with imaging features and differential diagnosis: a rare case report and literature review. Investig Magn Reson Imaging 2019;23:385-389 https://doi.org/10.13104/imri.2019.23.4.385
  14. Kashiwagi N, Dote K, Kawano K, et al. MRI findings of mucoepidermoid carcinoma of the parotid gland: correlation with pathological features. Br J Radiol 2012;85:709-713 https://doi.org/10.1259/bjr/55639432