The Journal of Pediatrics of Korean Medicine (대한한방소아과학회지)

The Association of Korean Oriental Pediatrics (대한한방소아과학회)
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A Literature Review of Experimental Study about Herbal Medicine for Bone Growth

한약제제의 골성장 효과에 대한 국내외 실험 연구 고찰

  • Kim, Tae-Jeong (Semyung University Chungju Korean Medicine Hospital) ;
  • Kim, Dong-Yeon (College of Korean Medicine, Semyung University) ;
  • Yang, Hee-Won (College of Korean Medicine, Semyung University) ;
  • Choi, Dong-Gun (College of Korean Medicine, Semyung University) ;
  • Kwon, Na-Yoen (Dept. of Pediatrics, College of Korean Medicine, Semyung University) ;
  • Lee, Dong-Nyung (Dept. of Pediatrics, College of Korean Medicine, Semyung University) ;
  • Sung, Hyun-Kyung (Dept. of Korean Obstetrics and Gynecology, College of Korean Medicine, Semyung University)
  • 김태정 (세명대학교 충주한방병원) ;
  • 김동연 (세명대학교 한의과대학) ;
  • 양희원 (세명대학교 한의과대학) ;
  • 최동건 (세명대학교 한의과대학) ;
  • 권나연 (세명대학교 한의과대학 한방부인과교실) ;
  • 이동녕 (세명대학교 한의과대학 한방부인과교실) ;
  • 성현경 (세명대학교 한의과대학 한방소아과교실)
  • Received : 2021.05.14
  • Accepted : 2021.08.23
  • Published : 2021.08.31
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Abstract

Objectives The purpose of this study is to investigate the effect of herbal medicine on bone growth and growth factors by collecting and analyzing domestic and foreign experimental research papers to establish a platform for future research. Methods Experimental studies published before March 2021 were searched using 7 Korean databases and 2 foreign databases. Among the numbers of studies searched, 48 experimental studies met the criteria and were selected. The results of those 48 studies upon herbal medicine administration were analyzed by bone growth, growth plate, weight. Results 23 studies mainly used monotherapy of either Astragali Radix and Cervi Parvum Cornu. 28 studies used combination of Poria Sclerotium, Dioscoreae Rhizoma, and Acanthopanacis Cortex. Among all studies selected, weight, bone growth, Insulin-like growth factor-1 (IGF-1) and Growth hormone (GH) were increased, but the increase was significant only in some of the studies. Conclusions The result of this study can be utilized as a background information for further studies and treatment in pediatric growth. Further randomized control studies are needed to underscore the finding.

Keywords

Acknowledgement

본 과제 (결과물)는 2020년도 교육부의 재원으로 한국연구재단의 지원을 받아 수행된 지자체-대학 협력기반 지역혁신 사업의 결과입니다.

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