Journal of the Korean Society of Physical Medicine (대한물리의학회지)

The Korean Society of Physical Medicine (대한물리의학회)
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Effect of Acute Phase Pain Control Using TENS on Pain Relief in Knee Osteoarthritis in a Rat Model

  • Chen, Chang-Da (Department of Rehabilitation Sciences, Graduate School, Daegu University) ;
  • Kim, Seung-Kyu (Department of Rehabilitation Sciences, Graduate School, Daegu University) ;
  • HwangBo, Gak (Department of Physical Therapy, College of Rehabilitation Sciences, Daegu University)
  • Received : 2021.04.19
  • Accepted : 2021.08.04
  • Published : 2021.08.31
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Abstract

PURPOSE: This study examined the influence of treadmill exercise with initial pain control using transcutaneous electrical nerve stimulation (TENS) on induced pain of knee osteoarthritis in rats. METHODS: Thirty adult male Sprague - Dawley rats were divided randomly into the TENS Group (TG, n = 10), Treadmill Exercise Group (TEG, n = 10), and Treadmill with TENS Group (TTG, n = 10). In the TG, TENS was performed for 20 min per day for two weeks with a TENS program at the knee joint. The TEG performed treadmill exercise 15 m/min for 20 min per day for two weeks. The TTG performed initial pain control by TENS program during the 1st ~ 3rd days, and treadmill exercise was performed using the TEG methods from the 4th day. The lumbar spine was extracted and processed using western blot analysis to evaluate pain (c-fos expression). RESULTS: The results showed that c-fos expression was decreased significantly in all groups after each intervention (p < .05). In particular, TTG produced the most significant decrease compared to the other groups. CONCLUSION: These results suggest that treadmill exercise with initial pain control using TENS is a suitable method for relieving pain in knee osteoarthritis.

Keywords

Acknowledgement

This thesis was researched with support from the Daegu University intramural academic research fund (20170337).

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