Archives of Craniofacial Surgery (대한두개안면성형외과학회지)

Korean Cleft Palate-Craniofacial Association (대한두개안면성형외과학회)
권호 표지
DOI QR코드

DOI QR Code

Primary cutaneous CD4+ small/medium T-cell lymphoma: a case report

  • Kim, Jeenam (Department of Plastic and Reconstructive Surgery, Konkuk University Medical Center) ;
  • Jeong, Minkyoung (Department of Plastic and Reconstructive Surgery, Konkuk University Medical Center) ;
  • Jun, Dongkeun (Department of Plastic and Reconstructive Surgery, Konkuk University Medical Center) ;
  • Lee, Myungchul (Department of Plastic and Reconstructive Surgery, Konkuk University Medical Center) ;
  • Shin, Donghyeok (Department of Plastic and Reconstructive Surgery, Konkuk University Medical Center) ;
  • Kim, Wookyoun (Department of Pathology, Konkuk University Medical Center) ;
  • Choi, Hyungo (Department of Plastic and Reconstructive Surgery, Konkuk University Medical Center)
  • Received : 2021.05.12
  • Accepted : 2021.08.11
  • Published : 2021.08.20
Download PDF
⟨ Previous Next ⟩

Abstract

Primary cutaneous CD4+ small/medium T-cell lymphoproliferative disorder is a rare disease characterized by a single mass on the face or upper part of the trunk. It usually presents an asymptomatic and favorable progression, and its histopathologic findings include small and medium-sized lymphoid cells. The authors report a case of primary cutaneous CD4+ small/medium T-cell lymphoproliferative disorder on the forehead. A 51-year-old man presented with a protruding mass on his forehead that the patient had noted 1 month previously. Surgical excision and a permanent biopsy were performed under local anesthesia. Based on the biopsy results, the mass was diagnosed as a primary cutaneous CD4+ small/medium T-cell lymphoproliferative disorder. There was no evidence of recurrence at a 15-month follow-up visit.

Keywords

References

  1. Willemze R, Cerroni L, Kempf W, Berti E, Facchetti F, Swerdlow SH, et al. The 2018 update of the WHO-EORTC classification for primary cutaneous lymphomas. Blood 2019;133:1703-14. https://doi.org/10.1182/blood-2018-11-881268
  2. Swerdlow SH, Campo E, Pileri SA, Harris NL, Stein H, Siebert R, et al. The 2016 revision of the World Health Organization classification of lymphoid neoplasms. Blood 2016;127:2375-90. https://doi.org/10.1182/blood-2016-01-643569
  3. Beltraminelli H, Leinweber B, Kerl H, Cerroni L. Primary cutaneous CD4+ small-/medium-sized pleomorphic T-cell lymphoma: a cutaneous nodular proliferation of pleomorphic T lymphocytes of undetermined significance? A study of 136 cases. Am J Dermatopathol 2009;31:317-22. https://doi.org/10.1097/DAD.0b013e31819f19bb
  4. Salah E. Primary cutaneous CD4+ small/medium pleomorphic T-cell lymphoproliferative disorder: where do we stand? A systematic review. J Dtsch Dermatol Ges 2019;17:123-36.
  5. Li D, Guo B, Li D, Chang C, Lu Q. Primary cutaneous CD4+ small-to-medium-sized pleomorphic T-cell lymphoma: a rare case report of infant. J Clin Pathol 2015;68:855-8. https://doi.org/10.1136/jclinpath-2015-203113
  6. Garcia-Herrera A, Colomo L, Camos M, Carreras J, Balague O, Martinez A, et al. Primary cutaneous small/medium CD4+ Tcell lymphomas: a heterogeneous group of tumors with different clinicopathologic features and outcome. J Clin Oncol 2008;26:3364-71. https://doi.org/10.1200/JCO.2008.16.1307
  7. Grogg KL, Jung S, Erickson LA, McClure RF, Dogan A. Primary cutaneous CD4-positive small/medium-sized pleomorphic T-cell lymphoma: a clonal T-cell lymphoproliferative disorder with indolent behavior. Mod Pathol 2008;21:708-15. https://doi.org/10.1038/modpathol.2008.40
  8. Alberti-Violetti S, Torres-Cabala CA, Talpur R, Corti L, Fanoni D, Venegoni L, et al. Clinicopathological and molecular study of primary cutaneous CD4+ small/medium-sized pleomorphic T-cell lymphoma. J Cutan Pathol 2016;43:1121-30. https://doi.org/10.1111/cup.12806
  9. Shi HZ, Zhang J, Xiong JS, Gan L, Jiang YQ, Xu XL, et al. Clinicopathological analysis of primary cutaneous CD4-positive small/medium pleomorphic T-cell lymphoproliferative disorder: a retrospective study of 22 patients. Int J Dermatol 2021;60:497-502. https://doi.org/10.1111/ijd.15372
  10. Baum CL, Link BK, Neppalli VT, Swick BL, Liu V. Reappraisal of the provisional entity primary cutaneous CD4+ small/medium pleomorphic T-cell lymphoma: a series of 10 adult and pediatric patients and review of the literature. J Am Acad Dermatol 2011;65:739-48. https://doi.org/10.1016/j.jaad.2010.07.028
  11. Toberer F, Hartschuh W, Hadaschik E. Primary cutaneous CD4+ small- to +medium-sized pleomorphic T-cell lymphoma: temporary remission by oral doxycycline. JAMA Dermatol 2013;149:956-9. https://doi.org/10.1001/jamadermatol.2013.4162
  12. Maurelli M, Colato C, Gisondi P, Girolomoni G. Primary cutaneous CD4+ small/medium pleomorphic T-cell lymphoproliferative disorder: a case series. J Cutan Med Surg 2017;21:502-6. https://doi.org/10.1177/1203475417715209
  13. Keeling BH, Gavino ACP, Admirand J, Soldano AC. Primary cutaneous CD4-positive small/medium-sized pleomorphic Tcell lymphoproliferative disorder: report of a case and review of the literature. J Cutan Pathol 2017;44:944-7. https://doi.org/10.1111/cup.13011

Cited by

  1. Early diagnosis and surgical treatment of primary cutaneous marginal zone B-cell lymphomas of the face in an Asian patient vol.22, pp.5, 2021, https://doi.org/10.7181/acfs.2021.00472