DOI QR코드

DOI QR Code

A Case Study on Performance Analysis of Antimicrobial Copper Film Attaching to Window for Responding to COVID-19 and Others

코로나19 등 대응을 위한 "유리창 부착용 항바이러스 동필름" 성능분석 사례연구

  • Received : 2020.09.07
  • Accepted : 2021.01.29
  • Published : 2021.03.31

Abstract

In the era of the global coronal 19 pandemic, there is a risk of cross-infection in hospitals at the stage where treatments and vaccines are currently being developed and marketed, so individuals should enhance their acquired immunity and generalize their living systems by the performance of copper ions in the social environment. In order to prevent the spread of infection, the need for anti-bacterial film and its efficacy were analyzed through anti-viral performance tests based on research and development cases of worldwide and immemorial time. he Korea Construction Research Institute (KCL) has received anti-bacterial performance certification and anti-viral test scores from the "National Approval Performance Certification Agency." At the time, NCCP 43326 Human Corona virus (BetaCoV/Korea/KCDC03/2020), which was approved by the Centers for Disease Control and Prevention, was introduced to ensure that the activity rate of infected cells was satisfied in the anti-viral performance test. Anti-proliferation measures for the Corona 19 virus require a quality clinical trial study comparing the experimental group within the glass space where the antiviral copper film is constructed with the comparator of the same condition without copper film.

세계적인 코로나19 대유행의 시대에, 현재 치료제·백신이 개발, 시판 중인 단계에서 병원내 교차감염의 위험성이 있는 상황이므로, 개인적으로는 후천적인 면역력을 제고하고 사회환경적으로 구리이온의 성능에 의한 생활방역체제를 일반화해야 한다. 감염확산방지를 위해 동서고금의 연구개발사례를 근거로 항균동 필름의 필요성 및 항바이러스 성능실험을 통해 효능성을 분석했다. 한국건설생활환경시험연구원(KCL)에서 항균성능인증 및 "국가승인 성능인증기관"에서 항바이러스 시험성적 인증을 받게 되었다. 당시 질병관리본부의 허가를 받은 실험재료인 NCCP 43326 Human corona virus(BetaCoV/Korea/KCDC03/2020)을 분양받아 생물안전기준에 맞게 생체외 실험실에서 In Vitro시험 결과, 항바이러스 성능시험에서 감염된 세포의 활성제거율이 만족할만한 결과를 도출하고 성능을 인증받게 되었다. 항후 코로나19 바이러스 확산방지대책으로 항바이러스 동필름이 시공된 유리창 공간내에서의 실험군과 항균동필름이 없는 동일조건의 대조군을 비교하는 질(質)적인 임상실험연구가 추가 필요하다.

Keywords

References

  1. Anderson, D. G. and Michels, H. T. (2008). Continuous Reduction Test Results for MRSA on Copper Alloy C110.
  2. Bang, J. H. (2020). We Can Get Out of The Virus Panic. Through Using Antimicrobial Copper. Steel&Metal News.
  3. Dykstra, M. (2020). How COVID-19 Kills. Frontiers in Public Health.
  4. Giao, M. S., Wilks, S. A., and Keevil, C. W. (2015). Influence of Copper Surfaces on Biofilm Formation by Legionella Pneumophila in Potable Water. Biometals: An International Journal on the Role of Metal Ions in Biology, Biochemistry, and Medicine. 28: 329-339. https://doi.org/10.1007/s10534-015-9835-y
  5. Grass, G., Rensing, C., and Solioz, M. (2011). Metallic Copper as an Antimicrobial Surface. American Society for Microbiology Journals. 77(5): 1541-1547.
  6. Kim, D. Y. (2015). Antimicrobial Copper Re-illuminated by MERS : Need to Increase Awareness of Antimicrobial Copper and Spread Application in Korea. Metal World. Vol. 115. Seoul. S&M Media.
  7. Li, G., Fan, Y., Lai, Y., Han, T., Li, Z., Zhou, P., Pan, P., Wang, W., Hu, D., Liu, X., Zhang, Q., and Wu, J. (2020). Coronavirus Infections and Immune Responses. Journal of Medical Virology. 92(4): 424-432. https://doi.org/10.1002/jmv.25685
  8. Michels, H. T., Keevil, C. W., C. D. Salgado, and Schmidt, M. G.(2015). From Laboratory Research to a Clinical Trial: Copper Alloy Surfaces Kill Bacteria and Reduce Hospital-Acquired Infections. SAGE Journals. 9(1): 64-79.
  9. NARS (2020). NARS Anslysis. COVID-19: How We Are Handling the Outbreak. Seoul: National Assembly.
  10. Noyce, J. O., Michels, H., and Keevil, C. W. (2006a). Potential Use of Copper Surfaces to Reduce Survival of Epidemic Meticillin-Resistant Staphylococcus Aureus in the Healthcare Environment. The Journal of Hospital Infection. 63(3): 289-297. https://doi.org/10.1016/j.jhin.2005.12.008
  11. Noyce, J. O., Michels, H., and Keevil, C. W. (2006b). Use of Copper Cast Alloys to Control Escherichia Coli O-157 Cross- Contamination during Food Processing. Applied and Environmental Microbiology. 72(6): 4239-4244. https://doi.org/10.1128/AEM.02532-05
  12. Noyce, J. O., Michels, H., and Keevil, C. W. (2007). Inactivation of Influenza A Virus on Copper Versus Stainless Steel Surfaces. Applied and Environmental Microbiology. 73(8): 2748-2750. https://doi.org/10.1128/AEM.01139-06
  13. Ulrich, B. (1986). Risk Society, London: Sage Publications.
  14. Warnes, S. L. and Keevil, C. W. (2013). Inactivation of Norovirus on Dry Copper Alloy Surfaces. PloS One. 8: e75017. https://doi.org/10.1371/journal.pone.0075017
  15. Warnes, S. L., Caves, V., and Keevil, C. W. (2012a). Mechanism of Copper Surface Toxicity in Escherichia Coli O157. Environmental Microbiology. 14(7): 1730-1743. https://doi.org/10.1111/j.1462-2920.2011.02677.x
  16. Warnes, S. L., Green, S. M., Michels, H. T., and Keevil, C. W. (2010). Biocidal Efficacy of Copper Alloys Against Pathogenic Enterococci Involves Degradation of Genomic and Plasmid DNAs. Applied and Environmental Microbiology. 76(16): 5390-5401. https://doi.org/10.1128/AEM.03050-09
  17. Warnes, S. L., Highmore, C. J., and Keevil, C. W. (2012b). Horizontal Transfer of Antibiotic Resistance Genes on Abiotic Touch Surfaces : Implications for Public Health. mBio. 3: e00489.
  18. Warnes, S. L., Summersgill, E. N., and Keevil, C. W. (2015a). Inactivation of Murine Norovirus on a Range of Copper Alloy Surfaces is Accompanied by Loss of Capsid Integrity. Applied and Environmental Microbiology. 81(3): 1085-1091. https://doi.org/10.1128/AEM.03280-14
  19. Warnes., S. L., Little, Z. R. and Keevil, C. W. (2015b). Human Coronavirus 229E Remains Infectious on Common Touch Surface Materials. Centre for Biological Sciences, University of Southampton, United Kingdom. mBio. 6(6): e01697-15.
  20. Weaver, L., Michels, H. T., and Keevil, C. W. (2008). Survival of Clostridium Difficile on Copper and Steel: Futuristic Options for Hospital Hygiene. The Journal of Hospital Infection. 68(2): 145-151. https://doi.org/10.1016/j.jhin.2007.11.011
  21. Weaver, L., Michels, H. T., and Keevil, C. W. (2010a). Potential for Preventing Spread of Fungi in Air-conditioning Systems Constructed Using Copper Instead of Aluminium. Letters in Applied Microbiology. 50(1): 18-23. https://doi.org/10.1111/j.1472-765X.2009.02753.x
  22. Weaver, L., Noyce, J. O., Michels, H. T., and Keevil, C. W. (2010b). Potential Action of Copper Surfaces on Meticillin-Resistant Staphylococcus Aureus. Journal of Applied Microbiology. 109(6): 2200-2205. https://doi.org/10.1111/j.1365-2672.2010.04852.x